A Systematic Review and Meta-Analysis of Cancer Patients ...
Odds ratio (OR) and forest plots (random-effects model) were constructed for both primary and secondary outcomes. Results: This systematic review of 38 studies and meta-analysis of 181 323 patients from 26 studies included 23 736 cancer patients. Our meta-analysis shows that cancer patients with COVID-19 have a higher likelihood of death (n ...
Real-world treatment patterns and outcomes in small-cell lung cancer: a
Keywords: Small-cell lung cancer (SCLC), systematic literature review, treatment patterns, treatment outcomes, survival, real-world Introduction Approximately 10-15% of lung cancer cases are classified as small-cell lung cancer (SCLC), which is associated with an extremely poor rate of survival of 6.9% at 5 years from the point of diagnosis ...
Quality of life versus length of life considerations in cancer patients
A systematic review of the literature was conducted using MeSH terms: cancer, longevity or LoL, QoL, decision making, trade‐off, and health utility. Articles retrieved were published between 1942 and October 2018.
Systematic literature review of real-world evidence for treatments in
Literature search. An SLR was performed in accordance with the Cochrane Handbook for Systematic Reviews of Interventions [] and reported in alignment with the Preferred Reporting Items for Systematic Literature Reviews and Meta-Analyses (PRISMA) statement [] to identify all RWE studies assessing the effectiveness and safety of treatments used for patients with HR+/HER2- LABC/mBC following 1 L ...
Mortality due to cancer treatment delay: systematic review ...
Objective To quantify the association of cancer treatment delay and mortality for each four week increase in delay to inform cancer treatment pathways. Design Systematic review and meta-analysis. Data sources Published studies in Medline from 1 January 2000 to 10 April 2020. Eligibility criteria for selecting studies Curative, neoadjuvant, and adjuvant indications for surgery, systemic ...
The Supportive Care Needs of Cancer Patients: a Systematic Review
Subsequently, cancer patients have a wide range of needs. This study aims to identify and synthesise cancer patients' views about areas where they need support throughout their care. A systematic search of the literature from PsycInfo, Embase and Medline databases was conducted, and a narrative. Synthesis of results was carried out using the ...
A Systematic Literature Review of Health Utility Values in Breast Cancer
As seen in Figure 4a, most of the studies for early breast cancer derived utilities using the EQ-5D. One study with large sample size 99 (>1000) consistently found the early breast cancer health states to be between 0.58 and 0.81. The health utilities for advanced breast cancer states were mainly measured using direct methods (SG, TTO, and VAS).
A comprehensive systematic review of colorectal cancer ...
An extensive systematic review of literature remarked that most guidance methodological handbooks for updating CPGs recommended a two or 3-year window between updates.
Life goals in patients with cancer: a systematic review of the literature
Abstract. Objective: Purposes of this systematic review of life goal research in cancer patients were to (1) identify life goal characteristics and processes being examined, (2) describe instruments used to assess life goal constructs, (3) identify theoretical models being used to guide research, and (4) summarize what is known about the impact ...
A Systematic Literature Review of Breast Cancer Diagnosis ...
This systematic literature review will be helpful to the researchers due to the detailed analysis of different methodologies and in conducting further investigations. Breast cancer is one of the most common diseases in women; it can have long-term implications and can even be fatal.
Risks and benefits of anticancer drugs in advanced cancer ...
In this systematic review and meta-analysis, we show that advanced cancer patients who have exhausted standard of care treatments and participate in a randomized clinical trial with a control arm without any anticancer drug overall benefited from the experimental treatment when randomized into the experimental arms with a 42% decrease in the risk of disease progression and a 18% decrease in ...
The mortality burden of cachexia or weight loss ...
PRISMA, Preferred Reporting Items for Systematic Reviews and Meta-Analyses; SLR, systematic literature review; WL, weight loss. Reproduced (with modifications) from Bonomi PD et al. Mortality burden of pre-treatment weight loss in patients with non-small-cell lung cancer: A systematic literature review and meta-analysis.
The Supportive Care Needs of Cancer Patients: a Systematic Review
Cancer, and the complex nature of treatment, has a profound impact on lives of patients and their families. Subsequently, cancer patients have a wide range of needs. This study aims to identify and synthesise cancer patients' views about areas where they need support throughout their care. A systematic search of the literature from PsycInfo, Embase and Medline databases was conducted, and a ...
Full article: A systematic literature review and network meta-analysis
Primary liver cancer is the sixth most common malignancy worldwide, with an estimated 841,080 new cases diagnosed in 2018 [1]. ... A systematic literature review (SLR) was conducted to identify RCTs of first-line treatments for TACE-ineligible patients with unresectable HCC. Data on overall survival (OS) and progression-free survival were ...
Recurrence-Free Survival in Patients With Surgically ...
Recurrence-Free Survival in Patients With Surgically Resected Non-Small Cell Lung Cancer: A Systematic Literature Review and Meta-Analysis. Part of this article was presented at the 2023 American Thoracic Society International Conference, May 19-24, 2023, Washington, DC. ... This systematic literature review and meta-analysis were conducted on ...
Screening for Lung Cancer With Low-Dose Computed ...
This systematic review to support the 2021 US Preventive Services Task Force Recommendation Statement on screening for lung cancer summarizes published evidence about the relative benefits and harms of low-dose computed tomography to identify lung cancer in persons at high risk.
Systematic reviews and cancer research: a suggested stepwise approach
Suggested stepwise approach for the systematic review process. Step 1. Register protocol for systematic review of previous systematic reviews, with or without meta-analysis, in trial registry. Similar to clinical trials as well as original systematic reviews, with or without meta-analysis, registering a protocol prospectively for a SRPSR in a ...
Clinical implications of the family history in patients with lung
Compared to other malignancies, few studies have investigated the role of family history of cancer (FHC) in patients with lung cancer, yielding largely heterogeneous results. We performed a systematic literature review in accordance with PRISMA guidelines, searching the PubMed and Scopus databases from their inception to November 25, 2023, to identify studies reporting on the role of FHC in ...
Patient Navigation in Cancer Treatment: A Systematic Review
Patient navigation programs have been well-established in improving screening rates and diagnostic resolution. This systematic review aimed to characterize the multifaceted role of patient navigators within the realm of cancer treatment. Recent findings: A comprehensive electronic literature review of PubMed and Embase databases was conducted ...
Barriers to Cervical Cancer Screening: A Systematic Review
To better ensure that women in this high-risk group have equitable access to cervical cancer prevention and treatment—and thus better cancer outcomes—will require multilevel efforts that include an emphasis on improving the human connection in health care encounters and improving the nuts-and-bolts logistics related to accessing that care.
Guidance on Conducting a Systematic Literature Review
Literature reviews establish the foundation of academic inquires. However, in the planning field, we lack rigorous systematic reviews. In this article, through a systematic search on the methodology of literature review, we categorize a typology of literature reviews, discuss steps in conducting a systematic literature review, and provide suggestions on how to enhance rigor in literature ...
Update on Prevalence of Pain in Patients with Cancer 2022: A Systematic
This review aims to provide an overview of the prevalence and severity of pain in cancer patients in the 2014-2021 literature period. A systematic literature search was performed using the databases PubMed, Embase, CINAHL, and Cochrane. Titles and abstracts were screened, and full texts were evaluated and assessed on methodological quality.
Systematic literature review and network meta-analysis of ...
Aim: To compare pembrolizumab with competing interventions for previously untreated, unresectable or metastatic microsatellite instability-high or mismatch repair-deficient colorectal cancer.Method: Trials were identified via a systematic literature review and synthesized using a Bayesian network meta-analysis with time-varying hazard ratios (HRs). ...
Causal attribution of human papillomavirus genotypes to ...
The systematic review identified 1174 studies with 111 902 cases of HPV-positive ICC and 2 755 734 of normal cervical cytology. 17 HPV genotypes were considered causal to ICC, with ORs ranging widely from 48·3 (95% CI 45·7-50·9) for HPV16 to 1·4 (1·2-1·7) for HPV51.
Supplemental Evidence and Data Request on Blood-Based Tests for
In order to do so, we are supplementing the usual manual and electronic database searches of the literature by requesting information from the public ( e.g., details of studies conducted). We are looking for studies that report on Blood-based Tests for Multiple Cancer Screening: A Systematic Review.
A systematic literature review of real-world treatment outcomes of
Worldwide, there are >1800,000 new cases of lung cancer each year. [ 1] Approximately 15% of new lung cancer cases are small cell lung cancer (SCLC), [ 2] which is characterized by late diagnosis, poor prognosis, and high frequency of recurrence with existing treatments. [ 2 - 4] Lung cancer primarily affects older adults, with a median age ...
Risk factors for loneliness in patients with cancer: a systematic
Objective: To systematically review the literature on the severity and risk factors for loneliness in adult cancer patients. Methods: We systematically reviewed quantitative studies addressing loneliness in cancer patients. Exclusion criteria were absence of a validated loneliness questionnaire, and studies that focused on loneliness determined by specific circumstances, and not cancer in ...
Technique Variables Associated with Fast Bowling Performance: A ...
The aim of this study was to systematically review biomechanical literature related to cricket fast bowling performance and narratively synthesise findings to provide a comprehensive summary of key performance characteristics. The articles were finalised according to Preferred Reporting Items for Systematic Reviews (PRISMA) guidelines.
The mortality burden of cachexia or weight loss in patients ...
Cancer-associated cachexia is a multifactorial wasting disorder characterized by anorexia, unintentional weight loss (skeletal muscle mass with or without loss of fat mass), progressive functional impairment, and poor prognosis. This systematic literature review (SLR) examined the relationship betwe …
Alcohol consumption and risk of cancer: a systematic literature review
This review did not find any association between alcohol consumption and an increased risk of cancers of the lung, bladder, endometrium and ovary. It was also observed that alcohol consumption may be inversely related to thyroid cancer. Our systematic review has confirmed consumption of alcohol as a risk factor for the development of several ...
COMMENTS
Odds ratio (OR) and forest plots (random-effects model) were constructed for both primary and secondary outcomes. Results: This systematic review of 38 studies and meta-analysis of 181 323 patients from 26 studies included 23 736 cancer patients. Our meta-analysis shows that cancer patients with COVID-19 have a higher likelihood of death (n ...
Keywords: Small-cell lung cancer (SCLC), systematic literature review, treatment patterns, treatment outcomes, survival, real-world Introduction Approximately 10-15% of lung cancer cases are classified as small-cell lung cancer (SCLC), which is associated with an extremely poor rate of survival of 6.9% at 5 years from the point of diagnosis ...
A systematic review of the literature was conducted using MeSH terms: cancer, longevity or LoL, QoL, decision making, trade‐off, and health utility. Articles retrieved were published between 1942 and October 2018.
Literature search. An SLR was performed in accordance with the Cochrane Handbook for Systematic Reviews of Interventions [] and reported in alignment with the Preferred Reporting Items for Systematic Literature Reviews and Meta-Analyses (PRISMA) statement [] to identify all RWE studies assessing the effectiveness and safety of treatments used for patients with HR+/HER2- LABC/mBC following 1 L ...
Objective To quantify the association of cancer treatment delay and mortality for each four week increase in delay to inform cancer treatment pathways. Design Systematic review and meta-analysis. Data sources Published studies in Medline from 1 January 2000 to 10 April 2020. Eligibility criteria for selecting studies Curative, neoadjuvant, and adjuvant indications for surgery, systemic ...
Subsequently, cancer patients have a wide range of needs. This study aims to identify and synthesise cancer patients' views about areas where they need support throughout their care. A systematic search of the literature from PsycInfo, Embase and Medline databases was conducted, and a narrative. Synthesis of results was carried out using the ...
As seen in Figure 4a, most of the studies for early breast cancer derived utilities using the EQ-5D. One study with large sample size 99 (>1000) consistently found the early breast cancer health states to be between 0.58 and 0.81. The health utilities for advanced breast cancer states were mainly measured using direct methods (SG, TTO, and VAS).
An extensive systematic review of literature remarked that most guidance methodological handbooks for updating CPGs recommended a two or 3-year window between updates.
Abstract. Objective: Purposes of this systematic review of life goal research in cancer patients were to (1) identify life goal characteristics and processes being examined, (2) describe instruments used to assess life goal constructs, (3) identify theoretical models being used to guide research, and (4) summarize what is known about the impact ...
This systematic literature review will be helpful to the researchers due to the detailed analysis of different methodologies and in conducting further investigations. Breast cancer is one of the most common diseases in women; it can have long-term implications and can even be fatal.
In this systematic review and meta-analysis, we show that advanced cancer patients who have exhausted standard of care treatments and participate in a randomized clinical trial with a control arm without any anticancer drug overall benefited from the experimental treatment when randomized into the experimental arms with a 42% decrease in the risk of disease progression and a 18% decrease in ...
PRISMA, Preferred Reporting Items for Systematic Reviews and Meta-Analyses; SLR, systematic literature review; WL, weight loss. Reproduced (with modifications) from Bonomi PD et al. Mortality burden of pre-treatment weight loss in patients with non-small-cell lung cancer: A systematic literature review and meta-analysis.
Cancer, and the complex nature of treatment, has a profound impact on lives of patients and their families. Subsequently, cancer patients have a wide range of needs. This study aims to identify and synthesise cancer patients' views about areas where they need support throughout their care. A systematic search of the literature from PsycInfo, Embase and Medline databases was conducted, and a ...
Primary liver cancer is the sixth most common malignancy worldwide, with an estimated 841,080 new cases diagnosed in 2018 [1]. ... A systematic literature review (SLR) was conducted to identify RCTs of first-line treatments for TACE-ineligible patients with unresectable HCC. Data on overall survival (OS) and progression-free survival were ...
Recurrence-Free Survival in Patients With Surgically Resected Non-Small Cell Lung Cancer: A Systematic Literature Review and Meta-Analysis. Part of this article was presented at the 2023 American Thoracic Society International Conference, May 19-24, 2023, Washington, DC. ... This systematic literature review and meta-analysis were conducted on ...
This systematic review to support the 2021 US Preventive Services Task Force Recommendation Statement on screening for lung cancer summarizes published evidence about the relative benefits and harms of low-dose computed tomography to identify lung cancer in persons at high risk.
Suggested stepwise approach for the systematic review process. Step 1. Register protocol for systematic review of previous systematic reviews, with or without meta-analysis, in trial registry. Similar to clinical trials as well as original systematic reviews, with or without meta-analysis, registering a protocol prospectively for a SRPSR in a ...
Compared to other malignancies, few studies have investigated the role of family history of cancer (FHC) in patients with lung cancer, yielding largely heterogeneous results. We performed a systematic literature review in accordance with PRISMA guidelines, searching the PubMed and Scopus databases from their inception to November 25, 2023, to identify studies reporting on the role of FHC in ...
Patient navigation programs have been well-established in improving screening rates and diagnostic resolution. This systematic review aimed to characterize the multifaceted role of patient navigators within the realm of cancer treatment. Recent findings: A comprehensive electronic literature review of PubMed and Embase databases was conducted ...
To better ensure that women in this high-risk group have equitable access to cervical cancer prevention and treatment—and thus better cancer outcomes—will require multilevel efforts that include an emphasis on improving the human connection in health care encounters and improving the nuts-and-bolts logistics related to accessing that care.
Literature reviews establish the foundation of academic inquires. However, in the planning field, we lack rigorous systematic reviews. In this article, through a systematic search on the methodology of literature review, we categorize a typology of literature reviews, discuss steps in conducting a systematic literature review, and provide suggestions on how to enhance rigor in literature ...
This review aims to provide an overview of the prevalence and severity of pain in cancer patients in the 2014-2021 literature period. A systematic literature search was performed using the databases PubMed, Embase, CINAHL, and Cochrane. Titles and abstracts were screened, and full texts were evaluated and assessed on methodological quality.
Aim: To compare pembrolizumab with competing interventions for previously untreated, unresectable or metastatic microsatellite instability-high or mismatch repair-deficient colorectal cancer.Method: Trials were identified via a systematic literature review and synthesized using a Bayesian network meta-analysis with time-varying hazard ratios (HRs). ...
The systematic review identified 1174 studies with 111 902 cases of HPV-positive ICC and 2 755 734 of normal cervical cytology. 17 HPV genotypes were considered causal to ICC, with ORs ranging widely from 48·3 (95% CI 45·7-50·9) for HPV16 to 1·4 (1·2-1·7) for HPV51.
In order to do so, we are supplementing the usual manual and electronic database searches of the literature by requesting information from the public ( e.g., details of studies conducted). We are looking for studies that report on Blood-based Tests for Multiple Cancer Screening: A Systematic Review.
Worldwide, there are >1800,000 new cases of lung cancer each year. [ 1] Approximately 15% of new lung cancer cases are small cell lung cancer (SCLC), [ 2] which is characterized by late diagnosis, poor prognosis, and high frequency of recurrence with existing treatments. [ 2 - 4] Lung cancer primarily affects older adults, with a median age ...
Objective: To systematically review the literature on the severity and risk factors for loneliness in adult cancer patients. Methods: We systematically reviewed quantitative studies addressing loneliness in cancer patients. Exclusion criteria were absence of a validated loneliness questionnaire, and studies that focused on loneliness determined by specific circumstances, and not cancer in ...
The aim of this study was to systematically review biomechanical literature related to cricket fast bowling performance and narratively synthesise findings to provide a comprehensive summary of key performance characteristics. The articles were finalised according to Preferred Reporting Items for Systematic Reviews (PRISMA) guidelines.
Cancer-associated cachexia is a multifactorial wasting disorder characterized by anorexia, unintentional weight loss (skeletal muscle mass with or without loss of fat mass), progressive functional impairment, and poor prognosis. This systematic literature review (SLR) examined the relationship betwe …
This review did not find any association between alcohol consumption and an increased risk of cancers of the lung, bladder, endometrium and ovary. It was also observed that alcohol consumption may be inversely related to thyroid cancer. Our systematic review has confirmed consumption of alcohol as a risk factor for the development of several ...