chemistry phd johns hopkins

Zanvyl Krieger School of Arts and Sciences

Department website: https://chemistry.jhu.edu/

The Department of Chemistry, in conjunction with other departments of the university, offers a broad education and the opportunity to do research in chemistry and related fields. The great diversity of the field of chemistry, ranging between physics and biology, is reflected in the research interests of the faculty. Undergraduate chemistry majors usually go on to graduate study in chemistry, chemical engineering, biology, oceanography, geochemistry, biophysics, environmental sciences, or medicine, while others enter the chemical industry. The Ph.D. in chemistry leads to professional careers in colleges and universities, research institutes, industry, and government laboratories.

The department is well-equipped with instrumentation, both shared and in individual faculty research laboratories, to perform modern chemical research. The Departmental Instrumentation Facility houses the following pieces of major instrumentation:

• Bruker Avance 400 MHz FT-NMR spectrometers (2), one located in the Instrumentation Facility in Remsen Hall and the other on the first floor of the New Chemistry Building.
• Bruker Avance 300 MHz FT-NMR spectrometer.
• Bruker Avance III 400 MHz FT-NMR spectrometer and Fourier 300 FT-NMR spectrometer with an automatic sample changer are located in the undergraduate teaching laboratory.
• Bruker Neo 500MHz Solid State NMR Spectrometer
• VG70S magnetic sector mass spectrometer, with EI, and CI ionization.
• VG70SE magnetic sector mass spectrometer, with FAB ionization.
• Finnigan LCQ Fleet ion trap Mass Spectrometer with ESI ionization and HPLC inlet.
• Waters Acquity / Xevo G2 UPLC-Q-ToF MS with ESI and APCI ionisation.
• Waters XevoG2-S – Standalone ESI mass spectrometer (can be equipped with ASAP)
• Thermo QEHF-X Orbitrap Mass Spectrometer with Ultimate 3000 NanoLC
• Bruker EMX EPR spectrometer equipped with a liquid helium cryostat and variable temperature controller.
• Jasco P-1010 polarimeter.
• SuperNova X-ray diffractometer (dual hi-flux micro-focus Mo and Cu sources) with Atlas CCD area detector (located on the second floor of the new chemistry building).
• Shimadzu QP2010SE GC-MS.
• Bruker AutoFlex Max Maldi Tof.
• Rigaku XtaLAB Synergy R equipped with a rotating-anode X-ray source (Cu Kα radiation) and HyPix-6000HE detector (located on the second floor of the new chemistry building).

NMR Facility

The NMR facility based in Remsen Hall consists of the three walk-up NMR (two in Remsen, one in the New Chemistry Building), an EPR and FTIR spectrometers, as well as a Polarimeter. In 2013, two new NMR spectrometers were purchased as part of the new Undergraduate Teaching Laboratories: a Bruker Avance III 400 MHz FT-NMR spectrometer and a Fourier 300 FT-NMR spectrometer with an automatic sample changer that can hold up to 60 samples. These can be used for research during the summer months when undergraduate labs are not in session. Upon checkout by the NMR facility manager, students are allowed to operate these instruments.

NMR spectrometers suitable for studies of biological macromolecules are located in the Biomolecular NMR Center, located in an underground facility in front of the New Chemistry Building. This center is a joint initiative of the departments of biology, biophysics, chemistry, and materials science, with additional collaboration from the School of Medicine’s departments of biochemistry and pharmacology. The instruments include 500, 600, and 800 MHz FT-NMR spectrometers. Scheduling for these spectrometers is handled by the center.

Mass Spectrometry Facility

A variety of different mass spectral techniques are available in the Mass Spectrometry Facility. High-resolution mass spectra of submitted samples are obtained on a service basis by a staff member using a magnetic sector instrument equipped with EI, CI, and FAB ionization methods. MALDI-TOF, GC/MS, and electrospray instruments are also available and operated by students and researchers following training by the facility staff.

X-ray Crystallography Facility

The X-ray Crystallography Facility is operated by a staff member. The facility is mainly concerned with the X-ray structure determinations of small molecules of new organic, inorganic, organometallic, and coordination compounds. Additionally, our dual-source Supernova diffractometer can perform crystal screening and collect data for protein crystals, and can collect high-quality data for tiny crystals.

Physical Sciences Machine Shop

The department shares the use of the Physical Sciences Machine Shop, located in Bloomberg Hall, with the Department of Physics and Astronomy. Electronics construction and repair is handled by a staff member in the Departmental Instrumentation Facility.

A department computer lab with Macintosh and Windows PC computers is available for undergraduate and graduate students to use.

In addition to the departmental instrumentation, individual research groups have acquired or constructed numerous pieces of specialized research instrumentation. A wide variety of laser systems, including Ar ion, Nd:YAG, excimer, dye lasers, and optical parametric oscillators are operational in individual faculty laboratories. Custom-built apparatuses include negative ion photoelectron spectrometers, UV and IR cavity ring-down spectrometers, electron energy-loss spectrometers, time-of-flight and magnetic mass spectrometers, molecular beam apparatus, UHV surface analysis apparatus, atomic-force microscopes, nanophase material generators, and a nanosecond time-resolved IR spectrometer.

The crystal growth facility of the Platform for the Accelerated Realization, Analysis, and Discovery of Interface Materials is located in Bloomberg Hall at Johns Hopkins University. For more information, including instructions for access, please visit the PARADIM website.

Undergraduate Program

Programs for undergraduate majors can be tailored to individual interests so that a major in chemistry is excellent preparation not only for further work in chemistry, but also for any field that rests on a chemical foundation. It is a good choice for a premedical student interested in medical research.

• Chemistry, Bachelor of Science
• Chemistry, PhD

For current course information and registration go to  https://sis.jhu.edu/classes/

Extradepartmental Studies

First year seminars, molecular microbiology and immunology.

The fundamental principles of chemistry, including atomic and molecular structure, bonding, elementary thermodynamics, equilibrium and acids and bases, are introduced in this course. Can be taken with Introductory Chemistry Laboratory – I unless lab has been previously completed. Note: Students taking this course and the laboratory 030.105 may not take any other course in the summer sessions and should devote full time to these subjects. High school physics and calculus are strongly recommended as prerequisites. First and second terms must be taken in sequence. Students not enrolled in college (unless they are rising freshmen) may not take this course.Course is offered in Summer and Fall terms only.

Distribution Area: Natural Sciences

AS Foundational Abilities: Science and Data (FA2)

Continuation of AS.030.101 emphasizing chemical kinetics, chemical bonding. Topics: energy levels and wave functions for particle-in-a-box and hydrogen atom and approximate wave functions for molecules including introduction to hybrid orbitals. Course is offered in Spring and Summer terms only.

Prerequisite(s): Students enrolled in AS.030.103 may not enroll in or receive credit for AS.030.102 .; AS.030.101

This course is designed for students who have scored a 4 or 5 on the AP Chemistry Exam or who have scored a 6 or 7 HL IB Chemistry Exam. This course will review an advanced introductory chemistry sequence in a single semester. Chemical equilibrium, reactivity and bonding will be covered. These topics will be explored through laboratory experiments and problem solving, and discussing these principles in the context of current research. For details on chemistry placement and exam credit policies, please see http://www.advising.jhu.edu/placement_chemistry.phpStudents who have previously enrolled in AS.030.101 or AS.030.105 may not earn credit for AS.030.103 and students enrolled in AS.030.103 may not enroll in or receive credit for AS.030.102 / AS.030.106 .

Prerequisite(s): Students must have completed Lab Safety training prior to registering for this class. To access the tutorial, login to myLearning and enter 458083 in the Search box to locate the appropriate module.

Chemistry is one of the oldest scientific disciplines through major contributions have been made in various fields such as health care, medicine, pharmaceutical sciences, materials and polymer science and forensic chemistry, to name a few. The development of new drugs involves chemical analysis and synthesis of new compounds. Chemistry also plays a vital role in the development and growth of several consumer-based industries such as pigments and paints, pharmaceuticals, cosmetics and oil and natural gas. In this program, students will be introduced to applications of chemistry in medicine and pharmaceutical sciences. Prerequisite: Background in chemistry and biology.

The experiments in this course are designed to support the learning of topics taught in AS.030.101 alongside developing your basic laboratory skills. They will provide students with a visual understanding of some of the key concepts of general chemistry and practice applying concepts to experimental procedures, observations, and results. Open only to those who are registered for or have successfully completed Introductory Chemistry 030.101. Course is offered in Summer and Fall terms only.

Prerequisite(s): Students enrolled in AS.030.105 may not enroll in AS.030.115, AS.030.103 , or AS.030.107.;Students must have completed Lab Safety training prior to registering for this class. To access the tutorial, login to myLearning and enter 458083 in the Search box to locate the appropriate module.;Students may take AS.030.101 at the same time as or complete it before enrolling in AS.030.105 .

Laboratory work includes some quantitative analysis and the measurement of physical properties. Open only to those who are registered for or have completed Introductory Chemistry II ( AS.030.102 ). Permission required for pre-college students.Course offered in Spring and Summer terms only.

Prerequisite(s): Students enrolled in AS.030.103 may not enroll in or receive credit for AS.030.106 .;Students must have completed Lab Safety training prior to registering for this class. To access the tutorial, login to myLearning and enter 458083 in the Search box to locate the appropriate module.; AS.030.105 AND AS.030.101

Many controversial health claims have entered the public consciousness over the years. Claims made by popular media are often conflicting and it can be difficult to trust their validity without directly examining their sources: data produced in scientific journals. However, the unfamiliar structure and technical jargon of these publications often act as a roadblock to understanding. This course aims to introduce common research methods and approaches and provide strategies for approaching research articles and interpreting their results using popular scientific topics as examples. Students will examine the biochemistry behind controversial topics such as CBD supplements, dieting, and gene editing and more importantly, build the skills to determine for themselves the validity of some of the many claims that enter the public consciousness.

The fundamental chemistry of the compounds of carbon. Methods of structure determination and synthesis. The mechanisms of typical organic reactions and the relations between physical and chemical properties and structures.Course offered only in Summer and Fall terms.

Prerequisite(s): AS.030.102 OR AS.030.103

Continuation of AS.030.205 Organic Chemistry I with special emphasis on organic synthesis and related synthetic methods. Students may not simultaneously enroll for AS.030.212 and AS.030.206 .Course only offered in Spring and Summer terms.

Prerequisite(s): AS.030.205

Corequisite(s): Students may not simultaneously enroll for AS.030.212 and AS.030.206 .

Second semester undergraduate organic chemistry from a more advanced prospective, emphasizing connections to modern examples from biochemistry (protein and DNA structure, chemical logic of metabolism, enzyme mechanisms), catalysis, materials (polymer synthesis, supramolecular chemistry), medicine (drug structure and function) and more. The standard topics of second semester organic chemistry (e.g. reactivity of aromatic and carbonyl-containing molecules) will all be covered, but amplified and enriched with topics as noted. Students may not simultaneously enroll in AS.030.212 and AS.030.206 . Prereq: Must receive a B+ or better in the first semester ( AS.030.205 )

Prerequisite(s): Must receive a B+ or better in the first semester ( AS.030.205 )

Laboratory work includes fundamental laboratory techniques and preparation of representative organic compounds. Open only to those who are registered for or have completed Introductory Organic Chemistry. Note: This one-semester course is offered each term. Introductory Organic Chemistry I/II requires one semester of the laboratory.

Prerequisite(s): Students must have completed Lab Safety training prior to registering for this class. To access the tutorial, login to myLearning and enter 458083 in the Search box to locate the appropriate module.; AS.030.205 AND (( AS.030.102 AND AS.030.106 ) OR AS.030.103 ) can be taken prior to enrolling or at the same time as AS.030.225 .

Corequisite(s): Students may not simultaneously enroll for AS.030.225 and AS.030.227

This is a project lab designed for Chemistry Majors who are concurrently enrolled in AS.030.205 .Techniques for the organic chemistry laboratory including methods of purification, isolation, synthesis, and analysis will be explored through a project focused on chemical chirality. Students may not simultaneously enroll for AS.030.225 and AS.030.227 .

Prerequisite(s): Students must have completed Lab Safety training prior to registering for this class. To access the tutorial, login to myLearning and enter 458083 in the Search box to locate the appropriate module.; AS.030.205 may be taken at the same time or prior to enrolling in AS.030.227 .

Corequisite(s): Students may not simultaneously enroll for AS.030.225 and AS.030.227 .

Lab skills already acquired in AS.030.225 will be further developed for synthesis, isolation, purification, and identification of organic compounds. Spectroscopic techniques, applications will be emphasized. Recommended Course Background: AS.030.225

Prerequisite(s): Students must have completed Lab Safety training prior to registering for this class. To access the tutorial, login to myLearning and enter 458083 in the Search box to locate the appropriate module.; AS.030.205 AND ( AS.030.225 OR AS.030.227 ); AS.030.206 OR AS.030.212 can be taken prior to enrolling in AS.030.228 OR at the same time as AS.030.228 .

AS Foundational Abilities: Science and Data (FA2), Projects and Methods (FA6)

This is a 3 credit lab that will serve as an introduction into analytical techniques and quantitative methods. There will be a 1 hour of pre-lab lecture component to this course to discuss the lab for that day.

Prerequisite(s): ( AS.030.102 OR AS.030.103 ) AND AS.030.205

AS Foundational Abilities: Writing and Communication (FA1), Science and Data (FA2), Projects and Methods (FA6)

Writing Intensive

The laws of thermodynamics, their statistical foundation, and their application to chemical phenomena. Students should have knowledge of general physics, general chemistry, and calculus (two semesters recommended). Freshmen by permission only.

Introduction to quantum mechanics, its application to simple problems for which classical mechanics fails. Topics: Harmonic oscillator, hydrogen atom, very approximate treatments of atoms and molecules, and theoretical basis for spectroscopy. Recommended Course Background: AS.030.301

This course is designed to illustrate the principles of physical chemistry and to introduce the student to techniques and instruments used in modern chemical research. Chemistry majors are expected to take this sequence of courses, rather than AS.030.307. Chemistry majors only.

Prerequisite(s): Students must have completed Lab Safety training prior to registering for this class. To access the tutorial, login to myLearning and enter 458083 in the Search box to locate the appropriate module..

Designed to illustrate the principles of physical chemistry, introduce the student to spectroscopic techniques and instruments used in modern chemical research. Chemistry majors are expected to take this course rather than 030.307.

Prerequisite(s): Students must have completed Lab Safety training prior to registering for this class. To access the tutorial, login to myLearning and enter 458083 in the Search box to locate the appropriate module.; AS.030.301 OR AS.030.302

This course will introduce students to the atomic origins of magnetism in real materials, with an emphasis on applications across a wide variety of fields. Beginning with a review of the quantum mechanical and chemical considerations that drive magnetic order, we will then explore how existing theoretical models can be used to describe unusual and often useful forms of magnetism. The latter half of the course will focus on the ways in which magnetic materials are commonly synthesized and characterized, and their importance in various electronic and medical applications. Finally, we will discuss recent advancements in the field, as well as the promise of such materials in the development of novel technologies.

Prerequisite(s): AS.030.102

In this class undergraduate students will be challenged to seek the connection between the material learned in class and recent scientific publications in the field. This course aim is to engage students with an organic chemistry background to think critically about major research publications, and to give them the tools to approach scientific literature with curiosity and confidence. Students will have the chance to read selected Nobel Prize winning scientific research from 2022 to 1902, from bioconjugation and click chemistry (2022) to molecular machines (2016), including capstones such as palladium catalyzed cross couplings (2010) to catalysis (2021). The aim is to build up an organic chemistry curriculum that will peak with the exploration of Retrosynthetic Analysis, introduced by E J Corey in 1990. This last concept will allow students to tackle overwhelming natural product synthesis papers, learning how to break down complex structures into simpler building blocks with recognizable reactivity. The introduction of high-stakes chemistry topics intro an upper-level course will allow students to ponder on their interests, future studies, or careers in the field.

Students will learn about the process behind modern chemical research, including the development of hypotheses, experimental design, statistical inference, scientific writing and communication, scientific ethics, and data presentation. Students will learn to become critical consumer of the primary scientific literature. Course will emphasize development of communication of research in the oral and written formats, which will be exercised through a peer-reviewed report, an oral presentation, and a poster presentation.

Laboratory designed to illustrate the principles and practice of inorganic chemistry through the synthesis and characterization of transition metal and organometallic compounds. Methods used include vacuum and inert atmosphere techniques. Instrumental approaches and modern spectroscopic techniques are applied to the characterization of compounds generated. It is strongly recommended that students have taken or are taking one of the following courses: AS.030.204, AS.030.442 , AS.030.449 , or AS.030.472.

Prerequisite(s): AS.030.228

This course provides an introduction to the vast chemistry and physics of solid-state materials. The course begins with a fundamental description of bonding in crystalline solids and calculation of electronic band structure. We then extend our discussion to methods for the synthesis of low-dimensional materials and hierarchical structures, including quantum dots (0D), nanowires (1D), graphene and graphene analogs (2D), and thin-film superlattices. An in-depth discussion of spectroscopic and characterization techniques for solid-state materials will follow and focus on some of the foundational studies of quantum devices and cooperative phenomena. At this stage we will describerecent advances in electron-microscopy (e.g. aberration-corrected and energy filtered TEM, atom-probe tomography) that are revolutionizing the structural, compositional, and electronic characterization of materials. The course will conclude with a survey of contemporary topics in solid-state and nanomaterials science, including functional devices and circuits, assembly, energy conversion and catalysis, and biological sensing.Recommended Course Background: AS.030.301 and AS.030.402 are preferred, but instructor approval may be granted in lieu of these courses.

This course will be focused on the fundamentals and applications of electrochemical methods in catalysis, charge transport, and energy conversion and storage. Topics that will be covered are basic electrochemical techniques, homogenous and heterogeneous (photo)electrocatalysis, fuel cells, and charge storage devices. The class will conclude with a group report and presentation on a recent development in the field of energy catalysis, conversion, and storage. Course topics include: 1) Fundamentals of electrochemistry, 2) Potential sweep methods and current-controlled techniques, 3) Impedance analysis, 4) Electrochemistry coupled with other characterization methods, 5) Electrocatalysis and photoelectrochemical catalysis, 6) Basics in fuel cells and current technologies (alkaline, polymer exchange membrane, solid oxide…), 7) Basics in batteries and current technologies (Pb acid, Li-based, other metals…)Recommended Course Background: AS.030.204 or AS.030.449 or AS.030.472, or instructor approval for undergraduate students. No pre-requisites for graduate students

This course provides an introduction to the state-of-the-art computational chemistry.The course integrates the basics about molecular electronic structure theories and the corresponding computational aspects and practice in chemical applications. The discussions of theories cover the modern quantum-chemical methods, ranging from mean-field methods (Hartree-Fock method and density-functional theory) to post mean-field methods for treating electron-correlation effects (configuration interaction and coupled cluster). Demonstrative calculations and computer lab practice are designed to deal with the computation of energetic properties (e.g., heat of formation,bond dissociation energy, reaction activation energy, etc) and structural properties (geometry, vibrational frequencies, etc) of representative molecular systems using standard quantum chemistry program package (the Gaussian program, most probably). The class will conclude with a report and presentation on a piece of recent computational work pertinent to the student’s research interests.

TA Course for Undergrads

This advanced (but descriptive) course focuses on how transition metals of the first row, i.e., iron, manganese and copper), process molecular oxygen (O2) in metalloenzymes and coordination complexes. Chemical behavior discussed will be reversible O2-binding (e.g., blood dioxygen carriers and their synthetic analogs), insertion of one or both atoms of molecular oxygen into organic substrates (i.e., oxygenase activity), or oxidase (bio)chemistry, wherein the metal ion center facilitates O2-reduction to hydrogen peroxide or water. The focus will be on the metal’s role and mechanism of action. Practical societal applications will also be discussed.

Prerequisite(s): AS.030.449 or equivalent

Advances in measurement techniques and simulations have driven an explosion in the variety, quality, and quantity of data collected when investigating chemical and materials processes. Advances in computing have led to the practicality of machine learning (ML) and related analytical methods to explore and extract meaning from this cornucopia of data, and data science has been called the fourth pillar of the scientific method. This course will provide an introduction to modern tools of data science, including the Python programming language, Jupyter notebooks, ML algorithms and their practical implementation, and high performance computing, with specific emphasis on applying these tools to data of chemical relevance, including UV/Vis, IR and NMR spectra, 3-D micro computed tomography, and physical property data including specific heat, magnetization, and resistivity.

Synthetic Biology is changing the world around us. This course is designed to help you to understand these powerful emerging technologies and the science behind it, and to help prepare you if you want to contribute toward these exciting developments.

Prerequisite(s): AS.030.315 OR AS.020.305

The course provides fundamental theoretical background for and emphasizes practical application of ultraviolet/visible and infrared spectroscopy, proton and carbon-13 nuclear magnetic resonance and mass spectrometry to the structure proof of organic compounds.

An introduction to organometallic chemistry beginning with structure, bonding, and reactivity and continuing into applications to fine chemical synthesis and catalysis. Required Course Background: Organic chemistry- I and -II. Level: Upper level Undergraduate AND Graduate Students

Physical and chemical properties of inorganic, coordination and organometallic compounds are discussed in terms of molecular orbital, ligand field and crystal field theories. Emphasis on structure and reactivity of these inorganic compounds. Other topics: magnetic properties, electronic spectra, magnetic resonance spectra, reaction kinetics.

The chemistry associated with surfaces and interfaces as well as a molecular level understanding of their essential roles in many technological fields. The first half of this course addresses various analytical techniques used to study surfaces including X-ray, photoelectron spectroscopy, and scanning tunneling microscopy. The second half of this course uses a number of case studies to illustrate the application of surface analytical techniques in contemporary research.

The principles of quantum mechanics are developed and applied to chemical problems.

Prerequisite(s): AS.030.302

This half-semester course introduces fundamental concepts in electrochemistry and the application of electrochemical methods for chemical research. The goal of this course is to enable students to practice electrochemistry in laboratory for any field. We will discuss how to use electrochemistry as an analytical technique in your toolbox for understanding chemical reactions as well as the role of electrochemistry in energy conversion and storage.

This class will introduce group theory in the chemical/physical context. In addition to the fundamentals of (practical/applied) group theory, this course will explore how the tools of group theory enable powerful, general statements to be made about the behavior of chemical systems from the atomics scale to the macroscale, often without requiring detailed calculations or knowledge of most microscopic details. It is particularly targeted at upper level chemistry and physics undergraduates who have a basic knowledge of quantum mechanics and a brief familiarity with linear algebra.

Research under the direction of members of the physical chemistry faculty.

Prerequisite(s): You must request Independent Academic Work using the Independent Academic Work form found in Student Self-Service: Registration, Online Forms.

Research under the direction of members of the inorganic chemistry faculty.

Research under the direction of members of the organic chemistry faculty.

Research under the direction of members of the biochemistry faculty.

Research under the direction of members of the biochemistry faculty. Recommended Course Background: AS.030.507 -AS.030.508 and permission of instructor.

Research under the direction of members of the Materials Chemistry faculty.

Research under the direction of the materials chemistry faculty.

Research under the direction of members of the medical faculty.

Research under the direction of Chemical Biology faculty. Permission of instructor required.

Research under the direction of the inorganic chemistry faculty. Recommended Course Background: AS.030.503 - AS.030.504 and permission of instructor.

Research under the direction of the physical chemistry faculty. Recommended Coures Background: AS.030.501 - AS.030.502 and permission of instructor.

Research under the direction of the organic chemistry faculty. Recommended Course Background: AS.030.505 - AS.030.506 and permission of instructor.

Research under the direction of members of the Organic Chemistry faculty.

Research under the direction of the chemistry faculty.

Research under the direction of members of the Inorganic Chemistry faculty.

Research under the direction of memebers of the Physical Chemistry faculty.

Research under the direction of Organic Chemistry faculty members.

Research under the direction of the chemistry faculty members.

An introduction to statistical mechanics of cooperative phenomena using lattice gases and polymers as the main models. Covered topics: phase transitions and critical phenomena, scaling laws, and the use of statistical mechanics to describe time dependent phenomena.

The molecular mechanism of elementary physical and chemical rate processes will be studied. Topics such as elastic scattering, collisional vibrational and rotational energy transfer, chemically reactive collisions, and the theory of unimolecular decay will be covered.

Is the chemistry that follows the break down of that sacred cow of low energy chemistry the Born-Oppenheimer approximation. Special attention is paid to the consequences geometric or Berry phase, molecular Aharonov-Bohm effect, the noncrossing rule, ubiquitous conical intersections and their surprising consequences. Examples from the modern literature will be emphasized.

Chemistry-Biology Interface (CBI) program students and faculty will meet weekly in a forum that will host presentations from CBI faculty and students as well as invited guest speakers. These meetings will serve as a valuable opportunity for students to develop presentation skills and interact with CBI students and faculty. Enrollment is required for first- and second-year CBI students, and is recommended for advanced-year graduate students.

Chemistry-Biology Interface (CBI) program students and faculty will meet weekly in a forum that will host presentations from CBI faculty and students as well as invited guest speakers. These meetings will serve as a valuable opportunity for students to develop presentation skills and interact with CBI students and faculty. Enrollment is required for first and second year CBI students, and is recommended for advanced year graduate students.

This course will cover fundamental principles in inorganic chemistry, biochemistry, and spectroscopy that are important to the field of bioinorganic chemistry. Current topics in bioinorganic chemistry will be covered, including metalloenzyme structure and function and related synthetic model systems. An emphasis will be placed on the role of transition metals in these systems, and their chemical mechanisms. The collection and interpretation of data from modern bioinorganic spectroscopic tools (e.g. UV-vis, EPR, raman, Mössbauer, X-ray absorption) will be discussed in the context of these current topics.

Parts I and II constitute the core course of the Chemistry-Biology Interface (CBI) Program. An introduction to the structure, synthesis, reactivity, and function of biological macromolecules (proteins, nucleic acids, carbohydrates, and lipids) will be provided using the principles of organic and inorganic chemistry. Discussion will incorporate a broad survey of molecular recognition and mechanistic considerations, and introduce the tools of molecular and cellular biology that are utilized in research at the interface of chemistry with biology and medicine. Recommended Course Background: AS.030.206 or equivalent.

Selected topics of current importance in chemical biology are covered. They include protein engineering and proteomics, cell signaling, protein-nucleic acid interactions (e.g. replication, transcription, DNA repair), catalytic RNA and the ribosome, biosynthesis of natural products, mechanisms of drug action, combinatorial chemistry and chemical genetics, and in vitro selection. Recommended Course Background: AS.030.619 or permission required.

Chemistry graduate students prepare and present their findings based upon approved chemistry literature of their choice.

Seminars are presented by advanced graduate students on topics from current chemical journals. Most first-year graduate students are expected to attend for credit. Undergraduates may take the course on a satisfactory/unsatisfactory basis.

Principles and methods for the design and optimization of new biological systems, from a molecular perspective. Topics include: introduction to genetic parts and modern methods for their assembly; synthesis and incorporation of nucleic acids at the level of nucleotides, genes, and genomes; design of genetic programs; library generation and screening; directed evolution and its application to create new proteins and metabolic pathways; computational design of protein and RNA?using physical and bioinformatic approaches; non-canonical amino acids and genetic code expansion. This course will also feature critical evaluation of the primary literature in this fast-paced field, and practical experience with relevant software and computational tools.

The course covers the application of techniques in physical chemistry to the study of organic reaction mechanisms. Topics include chemical bonding and structure, stereochemistry, conformational effects, molecular orbital theory, methods to determine reaction mechanisms, reactive intermediates, and photochemistry. Recommended Course Background: AS.030.205 - AS.030.206

This course covers advanced organic reactions and their mechanisms. Emphasis is given both to methods of postulating mechanisms for rationalizing reaction results and to the use of mechanistic thinking for designing reactions and reagents. This course is intended to be taken in sequence with AS.030.425. Recommended Course Background: AS.030.205 - AS.030.206

This course will introduce fundamental physical, chemical, and analytical concepts underlying light-induced chemical and (molecular-based) material processes. The final weeks of this course will build from these core concepts to survey molecular photoresponses and their consequences or applications in environmental chemistry, chemical biology, and materials science.

This is a natural products chemistry course organized according to the major natural product groups and emphasizing their origins, fundamental chemistry and applications in medicine. The organization is part traditional lecture and part case studies, like law school or business school, involving your participation in independent research, short essays and presentations. The last Workshops will be elective on your part as to topic with approval from C.A.T. Mixed in will be examples of organic and chemoenzymatic synthesis and biomimetic synthesis, relevant aspects of cofactor and enzyme function and their engineering, spectroscopic and kinetic tools.

This course is intended to be of general interest to those wanting to broaden their spectroscopy skills and will cover the theoretical and practical aspects of multidimensional NMR spectroscopy. This includes approaches to optimization of data acquisition and post-acquisition data processing as well as the development of the theoretical background needed to understand and design NMR pulse sequences.

This course will cover the principles and applications of photochemistry. The principles covered in this course will include the basics of light absorption, understanding atomic and molecular states, and the transitions between these states. Topics of application will include recent advances in photoredox chemistry and other means of photocatalysis. Discussions on techniques to probe these models and mechanisms will also be explored.

Biocatalysis is a rapidly evolving field that adapts biology’s mechanisms for innovation to offer revolutionary solutions for chemical production. This course features an in-depth coverage of various topics in biocatalysis with examples of how biocatalysis has reshaped various aspects of modern industries including food manufacturing, pharmaceuticals, consumer products, and biomaterials. This course also provides an overview of common enzyme classes used in bioindustries with extensive discussions of their catalytic mechanisms and engineering. Integrated within the course will be reviewing of important literatures, assessment of critical industrial biocatalytic processes, and hands-on experience of common bioinformatic and computational tools for new enzyme discovery.

The X-ray course will provide a complete approach to X-ray structure to determination (mostly concerned with snall molecules) and its uses in Chemistry. The first segment of this course will cover all theoretical aspects of X-ray crystallography, i.e. crystals and crystallixation, the nature of X-rays, the diffraction phenomenon of X-rays by crystals, symmetry and space groups, crystal structure analysis. Additionally, the course will provide laboratory experience for the students, involving hands-on instrumentation, experimental methodology to X-ray structure determination, structure solution/refinement, data analyses and publishing data. The course is aimed for graduate students with a strong interest in organic/inorganic chemistry, materials sciences, and physics. Undergraduate students with a major in chemistry are also encouraged to participate.

An exploration of modern synthetic methods in the context of total synthesis.

The reactions and principles involved in the synthesis of simple and complex organic compounds. Discussion of famous natural product syntheses and practice in developing rational designs for organic syntheses. Problems in the design of syntheses and in the use of chemical literature.

The course will begin with an overview of nucleic acid structure, synthesis and reactivity. Subsequent topics will include nucleic acid damage & repair, expanding the genetic code, the role of nucleic acids in epigenetics and applications in biotechnology, such as the development of nucleic acid sensors.

This course is for active Chemistry PhD students during summer terms

Open to AS Chemical Biology Interface Graduate Students only

TA Course for Grad Students

Open to AS Chemistry Graduate Students only.

Cross Listed Courses

NMR is a spectroscopic technique which provides unique, atomic level insights into the inner workings of biomolecules in aqueous solution and solid state. A wide variety of biophysical properties can be studied by solution state NMR, such as the three dimensional structures of biological macromolecules, their dynamical properties in solution, interactions with other molecules and their physical and chemical properties which modulate structure-function relationships (such electrostatics and redox chemistry). NMR exploits the exquisite sensitivity of magnetic properties of atomic nuclei to their local electronic (and therefore, chemical) environment. As a result, biophysical properties can be studied at atomic resolution, and the global properties of a molecule can be deconstructed in terms of detailed, atomic level information. In addition, interactions between nuclei can be exploited to enhance the information content of NMR spectra via multidimensional (2D and 3D) spectroscopy. Since these properties can be studied in solution, NMR methods serve as an effective complement to X-Ray crystallography and electron microscopy. In this course, we will learn about the basics of NMR spectroscopy, acquire 1D and 2D NMR spectra and use various NMR experiments to characterize and probe biophysical properties of proteins at an atomic level.

Prerequisite(s): Students must have completed Lab Safety training prior to registering for this class. To access the tutorial, login to myLearning and enter 458083 in the Search box to locate the appropriate module.;(( AS.030.101 AND AS.030.105 ) OR ( AS.030.103 OR AS.030.204)) AND (AS.030.370 OR AS.250.372 ) AND ( AS.020.305 OR AS.030.315 OR AS.250.315 ) AND AS.030.205 or permission of the instructor.

Foundation for advanced classes in Biophysics and other quantitative biological disciplines. This class is the first semester of a two semester course in biochemistry. Topics in Biochemistry I include chemical and physical properties of biomolecules and energetic principles of catabolic pathways.

Prerequisite(s): If you have completed AS.250.307 you may not register for AS.250.315 .;Students must have completed the following courses to enroll in AS.250.315 : AS.030.206 OR AS.030.212

Biochemical anabolism, nucleic acid structure, molecular basis of transcription, translation and regulation, signal transduction with an emphasis on physical concepts and chemical mechanisms. Format will include lectures and class discussion of readings from the literature.

Prerequisite(s): Students who have taken AS.030.316 are not eligible to take AS.250.316 .;( AS.250.315 OR AS.030.315 OR AS.020.305 ) AND ( AS.030.206 OR AS.030.212 ) or permission of the instructor.

Course covers classical and statistical thermodynamics, spanning from simple to complex systems. Major topics include the first and second law, gases, liquids, chemical mixtures and reactions, partition functions, conformational transitions in peptides and proteins, ligand binding, and allostery. Methods for thermodynamic analysis will be discussed, including calorimetry and spectroscopy. Students will develop and apply different thermodynamic potentials, learn about different types of ensembles and partition functions. Students will learn to use Pythonand will use it for data fitting and for statistical and mathematical analysis. Background: Calculus and Introductory Physics.

Discusses molecular, biochemical, cellular and immunological methodology and approaches for the mechanistic understanding, treatment and prevention of human diseases, and for understanding disease susceptibility. The focus will be on the application of biological methods and approaches to such critical issues as infectious disease, cancer, neurodegenerative disease, COPD, environmental toxicant effects on early development, and reproductive anomalies and their treatment.

Course location and modality is found on the JHSPH website .

Provides an opportunity for students to, in consultation with a faculty mentor from the Dept of Biochem and Molecular Bio, Environmental Health or Molecular Microbiology and Immunology, prepare a critical, scholarly paper on an agreed upon subject area.

This First-Year Seminar is designed to introduce students to the fundamental physical and chemical origins of color and how we perceive them - from the vivid palette provided by the natural world to the brightly colored clothing we wear. Beginning with the basic principles of light and color, we will embark on an interdisciplinary investigation of color, including, but not limited to: color chemistry; color in biology; the physiology of the eye; how color affects human psychology; the history of color and light; and the use of color in art. Discover the physical and chemical explanations behind several noteworthy phenomena such as sunsets, color-blindness, rainbows, fireworks, chameleons and the Aurora Borealis.

In this First-Year Seminar, we will seek to answer questions including: could you forge Beskar? What would it take to make a light saber? Is "Image, enhance" really possible? What is possible today? What might be possible in the future? And, what may never be possible, as it violates the laws of nature as we know them? We will take an empiricist approach, gathering data on the needed properties via screenings and related research, and then applying physical principles to reveal feasibility.

The past is littered with discoveries that have altered the course of civilization. In this First-Year Seminar, we will take a deep dive into chemical discoveries that changed history, discussing how they work as well as their impact on society. Topics will range from dirt warfare, to the link between gun powder and workers’ rights, to how cats biochemically domesticated humans.

Distribution Area: Humanities, Natural Sciences

This first year seminar will delve into the surprising ways that chemistry weaves its way through our day-to-day living. We will discuss topics that cover a variety of useful applications from "Chemistry in Medicine" to "Chemistry in Cooking & Baking". We will explore the material covered in our weekly discussions some more, by carrying out a few experiments to enhance our learning. No prior knowledge of chemistry in required.

Provides students with an overview of protein bioinformatics including computational and experimental approaches. Introduces amino acid and protein physical properties as well as the alignment and evolution of protein sequences. Presents protein structure and methods of structure determination as well as the use of protein databases and software for visualizing proteins and generating publication quality figures. Discusses methods for secondary and tertiary protein structure prediction including homology modeling. Also covers methods for modeling small/molecule-protein interactions within the context of rational drug discovery and design. Finally, introduces students to experimental and computational aspects of mapping protein interaction networks.

Acquaints students with the central concept of causation across the biomedical and public health disciplines. Discusses how cause and effect relationships govern today's research and evidence-based decision-making based on the social, physical, political, and economic determinants of health. Compares how fields and sub-disciplines in biomedicine and public health approach causation using research case examples that illustrate major morbidity and mortality-related health problems. Examines strategies to mitigate the limitations of causal inference.

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About the PhD in Biochemistry and Molecular Biology Program

In the Biochemistry and Molecular Biology PhD program, faculty, and students work together to increase knowledge of the biochemical and molecular bases of normal and abnormal cellular processes. Our program trains students to be successful independent scientists and gives them the knowledge, research training, and leadership skills to continue to provide new insights into the biomedical issues that have a profound impact on public health. Cancer biology is a historical and continuing area of interest for many faculty in our program, which has been supported in part by a training grant from the National Institutes of Health’s National Cancer Institute since 1975.

Students engage in a rigorous course curriculum and a range of structured and informal activities outside the classroom and lab to build their skills. They will pursue their thesis research in the lab of one of our over forty training faculty across the Johns Hopkins Bloomberg School of Public Health and the Johns Hopkins School of Medicine.

Visit our dedicated PhD program website to learn more about the diverse research training opportunities of the program.

PhD in Biochemistry and Molecular Biology Program Highlights

Our position within the School of Public Health provides a unique setting in which students learn how biochemistry, molecular biology, physical chemistry, cell biology, and genetics can be used to solve significant problems in public health and medicine. Our program offers:

• Training faculty from across the School of Public Health and the School of Medicine
• A strong grounding in the science of biomedical and public health research through a core curriculum that includes courses taught by leading experts from the Schools of Public Health and Medicine
• Training outside the lab and classroom in key skills such as communications and leadership
• Opportunities to build strong communications skills through a range of speaking venues including journal club, research colloquium, department retreats, and national meetings
• Teaching Assistant service to build teaching and interpersonal skills, with options for additional training and professional development through the Johns Hopkins University Teaching Academy to further develop skills
• Access to the Johns Hopkins School of Medicine Professional Development and Career Office , offering excellent career services and professional development,  including the BMB-required OPTIONS program, a guided process of career exploration for paths from medicine to biotech to academia and beyond
• Opportunities to participate in community service and outreach, with a focus on our East Baltimore neighborhoods, through the Johns Hopkins University community engagement and service-learning center, SOURCE

Training faculty across the School of Public Health and the School of Medicine

Schools that students can take courses in: Public Health, Arts & Sciences, Medicine, and Engineering

Two-month rotations in the first year prior to selecting thesis lab

Average number of incoming students in the BMB PhD degree program each year

What Can You Do With a PhD In Biochemistry And Molecular Biology?

The Biochemistry and Molecular Biology PhD program prepares students for a range of biomedical and health sciences careers, including in academia, industry, policy, and beyond. Visit the Graduate Employment Outcomes Dashboard to learn about Bloomberg School graduates' employment status, sector, and salaries.

Sample Careers

• Research Scientist
• Science Policy Adviser
• Biotech Executive
• Senior Scientist
• Patent Lawyer
• Science Policy Analyst/Advocate
• Science Writer/Journalist
• Biological Sciences Teacher

Topic Areas

The BMB PhD program faculty conduct research to gain new insights into the cellular and molecular mechanisms underlying normal and abnormal cellular processes, and their relevance as targets for improving health and treating disease. Our training program places particular emphasis on mechanistic approaches to research problems, and cancer biology has had a prominent place in our research interest for over 50 years .

Common topic areas within our faculty's diverse research interests include:

• Biophysics and Structural Biology
• Cancer Biology
• Chemical Biology and Proteomics
• Cell Biology
• Cellular Stress and Cell Signaling
• Genetics, Genomics, and Gene Regulation
• Immunology and Infectious Diseases
• Translational Research

Curriculum for the PhD in Biochemistry and Molecular Biology

The BMB PhD offers students a rigorous course curriculum, including a set of common core classes from the Schools of Public Health and Medicine. Students further tailor their curriculum with elective courses chosen based on interests and career goals, with options that span the Schools of Public Health, Medicine, Engineering, and Arts and Sciences. A rich array of seminar programs and journal clubs are also available to all students.

Browse an overview of the requirements for this PhD program in the JHU  Academic Catalogue  and explore all course offerings in the Bloomberg School  Course Directory .

Admissions Requirements

For the general admissions requirements see our How to Apply page. The specific program also requires:

Prior Research Experience

Laboratory research experience (from academia, industry, etc.) is required

Prior Coursework

Strong background in the sciences, particularly in chemistry, biochemistry, or biology

Standardized Test Scores

Standardized test scores (GRE) are optional for this program. The admissions committee will make no assumptions if a standardized test score is omitted from an application, but will require evidence of quantitative/analytical ability through other application components such as academic transcripts and/or supplemental questions.  Applications will be reviewed holistically based on all application components.

Program Faculty Spotlight

Ashani T. Weeraratna

Ashi Weeraratna, PhD, studies how cancer cells move to distant sites and how changes in the normal cells around a tumor contribute to their movement, especially as we age.

Michael J. Matunis

Michael Matunis, PhD, studies how protein modification by SUMO—the small ubiquitin-related modifier—drives changes in key cellular pathways from stress response to DNA repair.

Jennifer M. Kavran

Jennifer Kavran, PhD, MS, MPhil, is a biophysicist who investigates how cells communicate with each other and their environment.

Danfeng Cai

Danfeng Cai, PhD, combines advanced microscopy, genomics, and proteomics to tease out the functions of protein condensates in cells, with a focus on cancer.

Vivien Thomas PhD Scholars

The  Vivien Thomas Scholars Initiative (VTSI)  is an endowed fellowship program at Johns Hopkins for PhD students in STEM fields. It provides full tuition, stipend, and benefits while also providing targeted mentoring, networking, community, and professional development opportunities. Students who have attended a historically Black college and university (HBCU) or other minority serving institution (MSI) for undergraduate study are eligible to apply. To be considered for the VTSI, you will need to submit a SOPHAS application, VTSI supplementary materials, and all supporting documents (letters, transcripts, and test scores) by December 1, 2024. VTSI applicants are eligible for an application fee waiver , but the fee waiver must be requested by November 15, 2024 and prior to submission of the SOPHAS application.

Per the Collective Bargaining Agreement (CBA) with the JHU PhD Union, the minimum guaranteed 2025-2026 academic year stipend is $50,000 for all PhD students with a 4% increase the following year. Tuition, fees, and medical benefits are provided, including health insurance premiums for PhD student’s children and spouses of international students, depending on visa type. The minimum stipend and tuition coverage is guaranteed for at least the first four years of a BSPH PhD program; specific amounts and the number of years supported, as well as work expectations related to that stipend will vary across departments and funding source. Please refer to the  CBA to review specific benefits, compensation, and other terms.

In the BMB PhD program, all full-time PhD students who remain in good academic standing will receive the above support through the entire duration of the program.

Need-Based Relocation Grants Students who  are admitted to PhD programs at JHU starting in Fall 2023 or beyond can apply to receive a need-based grant to offset the costs of relocating to be able to attend JHU.   These grants provide funding to a portion of incoming students who, without this money, may otherwise not be able to afford to relocate to JHU for their PhD program. This is not a merit-based grant. Applications will be evaluated solely based on financial need.  View more information about the need-based relocation grants for PhD students .

Questions about the program? We're happy to help.

Mike Matunis, PhD PhD Program Director

Roza Selimyan , PhD BMB Executive Director for Academic Affairs and Education Programs

Erika Vaitekunas Administrative Specialist

[email protected]

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A Johns Hopkins postdoc, Herbert Baxter Adams, brought the seminar method of teaching from Germany, where he earned a PhD in 1876. The idea: That students would learn more by doing than by listening to lectures and taking exams.

That spirit of inquiry , of challenging the way things are done, lives on today in our nine academic divisions, all of which offer full-time graduate programs.

More information about our graduate programs is available below

School of Advanced International Studies

Students get global perspectives on today’s critical issues, with programs in international affairs , international studies , economics and finance , and public policy

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More than 60 full-time and part-time graduate programs spanning the arts , humanities , and natural and social sciences

Also see:   Part-time graduate options via Advanced Academic Programs

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The Carey Business School’s AACSB-accredited business programs provide students with the knowledge and skills necessary to be successful leaders and lifelong learners .

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Michael Wolfgang

855 N. Wolfe Street 475 Rangos  Baltimore MD 21205

The research in the Wolfgang laboratory utilizes biochemistry and molecular genetics to understand the molecular mechanisms used to sense and respond to nutritional/metabolic cues under various physiological and pathophysiological circumstances.  They are particularly interested in deciphering the roles of unexplored metabolic enzymes/pathways and determining novel roles of canonical metabolic pathways in cells and tissues that have been largely ignored by the metabolic community.  This includes cells in the nervous system and immune system as well as more classical metabolic models such as adipocytes and hepatocytes. Similar to the genomic landscape, there is an incredible amount of chemical metabolic space in cells that is critically important from a basic and clinical science standpoint that has been largely ignored.  The Wolfgang laboratory is trying to fill this large void.  To accomplish this they make heavy use of molecular biology and genetics to understand enzyme and metabolite biochemistry in vivo . The Wolfgang laboratory has also developed genetically-encoded sensors and chemical-genetic tools to overcome the technical obstacles facing the field of metabolic biochemistry

Selected Publications:

Bowman CE, Selen Alpergin ES, Cavagnini K, Smith DM, Scafidi S, Wolfgang MJ . “Maternal lipid metabolism directs fetal liver programming following nutrient stress.” Cell Reports 2019; 29:1299-1310

Lee J, Choi J, Selen Alpergin ES, Zhao L, Hartung T, Scafidi S, Riddle RC, Wolfgang MJ . “Loss of hepatic mitochondrial long chain fatty acid oxidation confers resistance to diet-induced obesity and glucose intolerance.” Cell Reports 2017; 20:655-667

Bowman CE, Rodriguez S,Selen-Alpergin E, Acoba MG, Zhao L, Hartung T, Claypool SM, Watkins PA, Wolfgang MJ . “The mammalian malonyl-CoA synthetase ACSF3 is required for mitochondrial protein malonylation and metabolic efficiency.” Cell Chemical Biology 2017; 24:673-684

Lee J, Choi J, Scafidi S, Wolfgang MJ . “Hepatic fatty acid oxidation restrains systemic catabolism during starvation.” Cell Reports 2016: 16: 201-212.

Bowman CE, Zhao L, Hartung T, Wolfgang MJ . “Requirement for the mitochondrial pyruvate carrier in mammalian development revealed by a hypomorphic allelic series.” Mol Cell Biol 2016; 36(15):2089-2104.

Lee J, Choi J, Aja S, Scafidi S, Wolfgang MJ . “Loss of adipose fatty acid oxidation does not potentiate obesity at thermoneutrality.” Cell Reports 2016; 14:1308-1316.

Nomura M, Liu J, Rovira IL, Gonzalez-Hurtado E, Lee J, Wolfgang MJ*, Finkel T.* “The role of fatty acid oxidation in macrophage polarization.” Nature Immunology 2016; 17(3): 216-217. (*Co-corresponding authors)

Lee J, Ellis JM, Wolfgang MJ . “Adipose fatty acid oxidation is required for thermogenesis and potentiates oxidative stress induced inflammation.” Cell Reports 2015; 10(2): 266-279. Ellis JM, Wong GW, Wolfgang MJ. “Acyl Coenzyme A Thioesterase 7 regulates neuronal fatty acid metabolism to prevent neurotoxicity.” Mol Cell Biol. 2013; 33(9) 1869-1882.

• Secondary Appointments
• Research Associates
• Postdoctoral Fellows
• Macromolecular Biophysics Core
• CryoEM Facility

Recent News

Jungsan sohn receives discovery award.

June 20, 2024

Congratulations to J Sohn, who has received a Discovery Award. This Johns Hopkins grant will fund a collaboration with Department

Ed Twomey receives Catalyst Award

Congratulations to Ed Twomey, who has received a Catalyst Award. This grant from Johns Hopkins funds exciting new research by

Chang Liu is named a Searle Scholar

June 7, 2024

Congratulations to Asst. Prof. Chang Liu, who has been named one of the 2024 Searle Scholars. This prestigious award provide

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Lori J. Sokoll , PhD

• Johns Hopkins School of Medicine Faculty

Primary Academic Title

Professor of Pathology

Lori J. Sokoll, Ph.D. is Professor of Pathology in the Johns Hopkins University School of Medicine and has secondary appointments in Oncology and Urology. She is Associate Director of the Clinical Chemistry Division and Director of the Special Chemistry Laboratory in the Johns Hopkins Hospital.

Dr. Sokoll has over twenty years of experience in laboratory testing for clinical and research purposes. As part of her clinical service in the Core Laboratories, she oversees immunoassay, endocrine, and tumor marker testing. Her research interests are focused on the measurement, evaluation, and clinical applications of cancer biomarkers, with a specific concentration on tumor markers for prostate cancer.

Dr. Sokoll received her A.B. degree from Cornell University, Master of Clinical Chemistry from Hahnemann University, and Ph.D. from Tufts University. She completed a two-year ComACC-accredited Postdoctoral Fellowship in Clinical Chemistry at the Johns Hopkins Medical Institutions.

Additional Academic Titles

Professor of Urology, Professor of Oncology

Research Summary

My primary research interest is the investigation of serum tumor markers for the early detection, diagnosis, staging, and monitoring of cancer. Our focus is to develop new tumor markers and to develop new applications for existing markers in order to increase their clinical utility. We are primarily studying markers for prostate cancer and ovarian cancer. Other research interests include immunoassay automation and intraoperative hormone measurements.

http://www.ncbi.nlm.nih.gov/pubmed/?term=sokoll+l

Tufts University

Hahnemann university hospital, board certifications, clinical chemist.

Thomas C. Jenkins Department of Biophysics

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Adip Jhaveri

Derin tanrioven, indrajit badvaram, iryna chelepis, richard yang.

Department of Chemistry

• Chemical Biology
• Inorganic Chemistry
• Materials Chemistry
• Organic Chemistry
• Physical Chemistry
• Theoretical Chemistry

Chemists are the architects of matter. Chemists design, build, and probe matter spanning multiple length-scales, from molecules and atomic clusters, to macro-molecular assemblies and crystalline solids. A crucial result of these efforts is that chemists can draw explicit links between the structure and composition of matter and its attendant physical properties. 

These links establish fundamental insight into the static and dynamic responses of matter to electromagnetic stimuli and also define the nature of matter-matter interactions, which determine the reactivity of species. Aside from its role as one of the core sciences, chemistry is at the heart of technology that has transformed industry and society.

Research Facilities

The department is well equipped with the instrumentation, both shared and in individual faculty research laboratories, to perform modern chemical research.

Our  Facilities  page has additional information for your research needs.

Research Areas

• Chemical Biology Examples of Chemical Biology pursued at Johns Hopkins include mechanisms of nucleic damage and repair, antibiotic biosynthesis, drug development, signaling pathways, catalysis, and enzyme engineering.
• Inorganic Chemistry Inorganic Chemistry at JHU is at the forefront of a wide range of research, including the study of coordination chemistry, bioinorganic chemistry, small molecule activation, enzyme mechanisms utilizing biological radicals, catalysis, and solid state and nanostructured functional materials.
• Materials Chemistry Our cross-disciplinary faculty are focused on the rational synthesis and characterization of new classes of organic, inorganic, and solid-state materials.
• Organic Chemistry Organic chemistry at JHU bridges both synthetic and physical organic chemistry. Current activities include research in synthetic methodology, materials, natural products, medicinal chemistry, and chemical biology.
• Physical Chemistry Physical Chemistry research at JHU spans many areas including fundamental molecular and atomic interactions, chemical and photochemical dynamics, catalysis, surface and materials chemistry, nanomaterials, protein biophysics, and molecular and materials spectroscopy.
• Theoretical Chemistry Theoretical chemistry at JHU develops and applies novel methods in chemical theory and computation.

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