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  • Published: 20 June 2024

The association of social networks and depression in community-dwelling older adults: a systematic review

  • Amelie Reiner   ORCID: orcid.org/0009-0002-8789-1303 1 &
  • Paula Steinhoff   ORCID: orcid.org/0009-0001-2973-963X 1  

Systematic Reviews volume  13 , Article number:  161 ( 2024 ) Cite this article

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Background and objective

Depression is a globally prevalent mental condition, particularly among older adults. Previous research has identified that social networks have a buffering effect on depression. Existing systematic reviews have either limited their research to specific geographic areas or provided evidence from over a decade ago. The vast body of recent literature particularly from the last decade emphasizes the need for a comprehensive review. This systematic review aims to analyze the association of structural aspects of social networks and depression in older adults.

The electronic databases APA PsycINFO, ProQuest, PSYINDEX, PubMed, Scopus, SocINDEX, and Web of Science were searched from date of data base inception until 11 July 2023. Studies were eligible for inclusion if they reported on community-dwelling older adults (defined as a mean age of at least 60 years old), had an acceptable definition for depression, referred to the term social network in the abstract, and were published in English. Quality was appraised using the Newcastle Ottawa Scale for cross-sectional and longitudinal studies. Outcome data were extracted independently from each study and analyzed by direction of the relationship, social network domain and cross-sectional or longitudinal study design.

In total, 127 studies were included. The study categorizes structural network aspects into seven domains and finds that larger and more diverse networks, along with closer social ties, help mitigate depression. The literature on the relationships between depression and network density, homogeneity, and geographical proximity is scarce and inconclusive.

Discussion and implications

Despite inconsistent findings, this review highlights the importance of quantifying complex social relations of older adults. Limitations of this review include publication and language bias as well as the exclusion of qualitative research. Further research should use longitudinal approaches to further investigate the reciprocal relationship between social networks and depression. Following this review, interventions should promote the integration of older adults in larger and more diverse social settings.

Other: This work was supported by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) under Grant [454899704]. This systematic review was pre-registered. The review-protocol can be accessed at https://doi.org/10.17605/OSF.IO/6QDPK .

Peer Review reports

Depression is a mental condition that is particularly prevalent among older adults [ 1 ]. Scholars have identified a significant association between social networks and depression, with socially integrated older adults showing lower levels of depression than less socially integrated older adults [ 2 , 3 ]. As older adults face a decreasing number of social relationships and a shrinking social network over their life course [ 4 ], this growing population is at risk for depression. Systematizing and quantifying the social networks of older adults is vital to understanding their relationship with depression. The prevalence of depression will increase in the future. Understanding the aspects of social networks that are particularly important for preventing depressive symptomatology in older adults will allow appropriate social gerontological interventions.

Previous systematic reviews have generated important insights into the relationship between social networks and mental health. Across several geographical areas, various social network measures have been found to be significantly associated with mental health in older adults (Middle Eastern countries: [ 5 ]; Iran: [ 6 ]), and specifically depression (Asia: [ 2 ]; Western countries: [ 7 ]). However, only one systematic review has addressed the relationship between social networks and depression among older adults without restricting its evidence to a geographical area [ 3 ]. While Schwarzbach et al.’s [ 3 ] review has been helpful, new evidence about the social relations of older adults and depression outcomes must be reviewed because a significant amount has emerged over the last decade.

Additionally, previous studies and literature reviews have loosely applied the concept of social networks and engaged with different definitions and measures of social networks [ 8 , 9 ]. A social network is traditionally defined as the quantifiable ties binding individuals, families, communities, or businesses (i.e., nodes) together through a shared need, aim, or interest [ 10 , 11 ]. The nature of one’s social network was found to have a significant influence on an individual’s life expectancy, mortality rate, quality of life, and health-related behaviors [ 8 ]. Generally, the literature has distinguished between the quantitative/structural and qualitative/functional aspects of social relationships [ 12 , 13 ]. Qualitative aspects refer to the social network’s function, including the potential of social relationships, such as social support, the perceived quality of support provided, relationship satisfaction, loneliness and social isolation [ 13 , 14 ]. In contrast, quantitative aspects refer to the network’s structure, including its size, composition, and the frequency of contact between network members. Recently, it has become increasingly clear that quantifying social networks, which provides an objective measure of the structure of relationships, is particularly suited for understanding their association with critical health outcomes, such as cognitive decline [ 14 ], dementia [ 15 ], and mortality [ 16 ]. As structural aspects of social networks are causally prior to functional aspects, this review exclusively focuses on their structural aspects while examining their relationship with depression in older adults.

The relationship between social networks and depression can be considered reciprocal. The main effect model [ 17 ] states that social networks positively affect psychological state through mechanisms such as social recognition, a sense of belonging, and normative guidance for health-promoting behavior. Conversely, depression may affect the extent of social networks by causing social withdrawal and decreased social participation. Older adults who experience depression in later life often struggle with maintaining larger and more diverse personal networks and experience disruptions in their contact with social network members [ 18 ]. Existing research has predominantly focused on the effect of social networks on depression. Conversely, the reversed effect of depression on social networks has been largely neglected [ 19 , 20 ].

This systematic review, therefore, aims to synthesize the evidence about the relationship between structural aspects of social networks and depression in community-dwelling older adults. It addresses two research questions: (1) How do structural aspects of social networks impact depression outcomes in community-dwelling older adults? (2) How does depression impact structural aspects of social networks of community-dwelling older adults? It strives to provide a comprehensive picture by gathering cross-sectional as well as longitudinal evidence and by focusing on the reciprocal relationship between social networks and depression in older adults.

This systematic review was pre-registered. The review-protocol can be accessed at https://doi.org/10.17605/OSF.IO/6QDPK . In addition, we followed PRISMA guidelines for the reporting of this systematic review ([ 21 ]; see Additional file 1, Table A1).

Eligibility criteria

We expected to include peer-reviewed articles on the association of structural social network characteristics and depression among community-dwelling older adults. Following the World Health Organization (WHO; [ 22 ]), we define older adults as those, being 60 years and older. To counteract possible regional selection bias induced by language knowledge, we focused on English publications only. We did not exclude studies based on publication year or geographic area.

Related previous systematic reviews informed the inclusion and exclusion criteria [ 2 , 3 , 5 , 6 , 7 , 8 , 13 , 23 , 24 , 25 ]. Articles were included if the population of interest consisted of community-dwelling adults, specifically those older than 40 years, with a study mean age of at least 60 years. We opted for a minimum age in order to include relevant age studies from the age of 40 (e.g., the German DEAS), but focused on older adults by deciding that the mean age of the study participants must be at least 60 years, following the definition of older adults. The exposure or outcome focused on social networks, explicitly mentioned in the abstract of the studies. Further exposure or outcome of interest was depression, with an acceptable definition involving diagnostic criteria or a cut-off point on a depression rating scale. The association between social networks and depression had to be reported using a multivariate analysis adjusting for any confounders (the specifics of the included confounders are evaluated in the quality assessment). Only peer-reviewed journal articles published in English were considered for inclusion. Articles were excluded if they focused on patient groups or included institutionalized individuals, unless the analyses separated community-dwelling and institutionalized participants. Additionally, studies were excluded if they referred to recalled social network characteristics from the past, such as youth and adolescence, to measure present depression outcomes, or if they exclusively focused on online social networks. In terms of study types, editorials, study protocols, conference proceedings, comments, reviews, qualitative studies, grey literature, case studies, and intervention studies were excluded. An overview of the studies that appeared to meet the inclusion criteria but were ultimately excluded and the reasons for this can be found in the Additional file 1, Table A2.

Search strategy

The systematic database search was performed from date of data base inception up to 11 July 2023. The keywords used for the search strategy included related terms for: “depression” AND “social networks” AND “older adults” (see pre-registered review protocol). These were informed by related systematic reviews about the three main terms [ 2 , 3 , 5 , 6 , 7 , 8 , 13 , 23 , 24 , 25 ]. The following seven databases were searched using the same keywords and search designs: APA PsycINFO, ProQuest, PSYINDEX, PubMed, Scopus, SocINDEX, and Web of Science. We also conducted manual searches for potentially eligible studies from reference lists of related systematic reviews [ 2 , 3 , 5 , 6 , 7 , 8 , 13 , 23 , 24 , 25 ].

Study selection

References from the seven databases were imported into Rayyan [ 26 ]. After deduplication, two researchers (AR, PS) independently screened titles and abstracts, forwarding potentially eligible papers for full text review. Two researchers (AR, PS) independently assessed the full text of potentially eligible citations against the eligibility criteria. Disagreements and discrepancies were resolved by consensus between the researchers. The study selection process was piloted twice with a random sample of a hundred studies of the overall sample per pilot. Piloting the study selection process improves the reliability and validity of the review by ensuring all reviewers have a clear and consistent understanding of the selection process [ 27 ].

Data extraction

Using a standardized data collection form informed by related reviews [ 2 , 3 , 5 , 6 , 7 , 8 , 13 , 23 , 24 , 25 ], two reviewers (AR, AL) independently extracted data on the study population including their sample size, average age and age range, gender ratio, and country. Further, we extracted information on the measurement of depression, the social network assessment, type of social ties, potential exclusion of population groups, data source, the statistical methods, and the results. The outcomes of interest were structural aspects of social networks and/or depression scores among community-dwelling older adults. Any disagreements were resolved by discussion. If this failed, a third reviewer (PS) was consulted. The data extraction process was piloted once with a random sample of twenty studies to ensure the completeness of all relevant information in the data collection form [ 28 ].

Quality appraisal

Quality was assessed using the Newcastle Ottawa Scale (NOS; [ 29 ]) for cross-sectional and longitudinal studies by one reviewer (AR) and double-checked by another reviewer (PS). The NOS has been used in systematic reviews before [ 2 , 30 , 31 , 32 ]. The NOS awards each article an amount of stars within three domains, with a greater number of stars indicate a higher‐quality study [ 29 ]. The study quality is evaluated in terms of design, participant selection, comparability and assessment of exposure and outcome. Following the approach of several reviews [ 2 , 31 , 32 ], we adopted a rigorous methodology to assess the quality of studies, adhering to predetermined thresholds for converting the NOS to Agency for Health Research and Quality (AHRQ) standards. For a cross-sectional study to be considered of good quality, it needed to attain between 3 and 5 stars in the selection domain, alongside 1 or 2 stars in the comparability domain, and finally, 2 or 3 stars in the outcome domain. Those studies that achieved 2 stars in the selection domain, coupled with 1 or 2 stars in comparability, and 2 or 3 stars in outcome were classified as fair quality. However, studies falling short of these criteria were deemed poor quality; they either obtained 0 or 1 star in the selection domain, 0 stars in comparability, or 0 or 1 stars in outcome. In contrast, a longitudinal study was considered of good quality if it garnered between 3 and 4 stars in the selection domain, along with 1 or 2 stars in the comparability domain, and finally, 2 or 3 stars in the outcome domain. Those longitudinal studies achieving 2 stars in the selection domain, paired with 1 or 2 stars in comparability, and 2 or 3 stars in outcome were categorized as fair quality. Conversely, studies failing to meet these benchmarks were classified as poor quality; they either received 0 or 1 star in the selection domain, 0 stars in comparability, or 0 or 1 stars in outcome. For the analyses, we included all studies irrespective of the quality assessment results. However, when excluding studies which were considered as poor quality in a sensitivity analysis, the results were found to remain largely stable.

Synthesis method

Citations were firstly sub-grouped by direction of the relationship, then by structural aspect of social networks, and afterwards by the cross-sectional or longitudinal study design. In a further step, we count the significant associations against the insignificant associations. We compare the significant results across study design to identify differences between cross-sectional and longitudinal relationships. Further, we compare the effects of interest across structural aspects of social networks in the discussion. Tables are used to display the sub-grouped evidence. Further comparisons were carried out by geographical location, gender, family versus friends’ social ties and functional versus structural social network aspects. Findings are reported narratively.

Sample description

Starting from an initial result of 47,702 entries, 26,915 unique citations were identified. The two authors (AR, PS) independently screened the titles and abstracts, resulting in 320 potentially eligible articles. Any disagreement over the eligibility of individual studies was resolved through discussion. After adhering to strict inclusion and exclusion criteria, 127 unique publications were identified. Figure 1 Visualizes a PRISMA flowchart of the selection process.

figure 1

HYPERLINK "sps:id::fig1||locator::gr1||MediaObject::0"Selection flowchart for papers included in the systematic review

The quality appraisal for each NOS-domain and overall evaluation can be found in the Additional file 1, Table A3 for cross-sectional studies and Table A4 for longitudinal studies. Two thirds of the studies ( n  = 86) were classified as good-quality studies, 27 articles with fair quality and 15 articles with poor quality.

The included articles were published between 1985 and 2023, with half published later than 2016. This highlights the vast body of research that has been conducted on this association, particularly in the last decade. The range of sample sizes was 53 to 60,918, with a median sample size of 1349 respondents. The geographic location of most of the studies was North America ( n  = 46), followed by Asian countries ( n  = 42). Thirty-four studies were conducted in European countries (and Israel), and only three were conducted in South American countries. One study has a mixed geographical location by comparing older adults in North America to those in Asia [ 33 ]. One study did not specify its geographic location [ 34 ].

The majority of studies made use of validated instruments to assess particularly depression. They either used various forms of the Center for Epidemiologic Studies Depression Scale (CES-D, n  = 58) or the Geriatric Depression Scale (GDS, n  = 42) to assess depression. Other studies used the EURO-D scale ( n  = 12), the Composite International Diagnostic Interview (CIDI, n  = 3), the nine-item Patient Health Questionnaire (PHQ-9, n  = 3), or other validated instruments ( n  = 9).

Most studies focused on the cross-sectional relationship between the social networks of older adults and depression ( n  = 96), while 30 articles examined the relationship longitudinally. Only one article had both a cross-sectional and longitudinal focus [ 35 ]. In most aspects of social networks, there were no apparent differences between the cross-sectional and longitudinal investigations. Additionally, 90% ( n  = 114) of the studies exclusively used depression as an outcome variable, while 6% ( n  = 8) exclusively used social network variables as outcome variables. Only five studies focused on the existence of a bi-directional relationship [ 19 , 20 , 36 , 37 , 38 ].

All risk factors for depression related to social networks used within the studies were categorized. Seven structural aspects of social networks were identified: network composition, contact frequency, network density, homo-/heterogeneity, network size, geographic proximity, and network scales. Table 1 provides an overview of the social network aspect descriptions. Notably, ties to friends and family were the covered most frequently in social network measures. The results were largely stable across geographic areas.

Depression as outcome variable

In total, 119 articles examined structural network aspects’ effects on depression. Ninety articles did so cross-sectionally, and 28 articles did so longitudinally. One article focused on the relationship both cross-sectionally and longitudinally [ 35 ].

Most publications focused on network scales ( n  = 44), network size ( n  = 44), network composition ( n  = 30), and contact frequency ( n  = 28) as structural network factors determining depression outcomes in older adults. Significantly fewer articles used density ( n  = 4), geographic proximity ( n  = 3), and homogeneity ( n  = 2). The results are presented below according to their frequency.

Network scales

Some articles used standardized network scales to examine various aspects of social networks’ effects on depression among older adults. Most articles used (modifications or translations of) the Lubben Social Network Scale (LSNS) or the Social Network Index (SNI), with higher scores indicating greater social engagement.

Most associations (40 out of 60 = 67%) between network scales and depression among older adults were reported to be significant (Table  2 ). No meaningful difference was identified between cross-sectional and longitudinal studies concerning effect significance or direction. Consistently, scholars found higher scores on social network scales to buffer depression outcomes among older adults. However, different subscales were used to assess family and friends variables. While some studies suggested that family networks were more predictive of depression outcomes in older adults [ 41 , 42 , 43 ], Singh et al. [ 44 ] indicated the opposite, suggesting that the friend network scale was significantly associated with depression. They found no significant associations in the children, relatives, and confidant network scales.

The results appear to be largely stable across gender. Most of the studies considering gender differences did not find the association of network scales and depression to differ in women and men [ 43 , 50 , 60 , 66 ]. The evidence of studies finding gender differences is inconclusive. While two studies found network scales to be only significant associated with depression in men but not women [ 68 , 80 ], another study found a significant association for the friends’ subscale in women but not men [ 47 ]. Conversely, no gender differences were found regarding the family subscale [ 47 ].

Network size

Network size was the most frequently studied variable besides network scales. In total, 66 measured associations were found in 44 articles (see Table  3 ). No meaningful difference was identified between cross-sectional and longitudinal studies concerning effect significance or direction. The results were inconclusive: Half of the studies found no significant association, while the other half provided significant evidence for an effect of social network size on depression in older adults. Of the effects significantly associated with depression, 32 of 33 were negative. This suggests that more extensive social networks are associated with lower levels of depression in older adults.

There seems to be no consensus regarding the association of the size of different social spheres and depression outcomes among older adults. While Palinkas et al. [ 64 ] and Harada et al. [ 96 ] found friend network size to be more important than relative network size, Lee and Chou [ 98 ] found these variables to be equally important. Furthermore, Minicuci et al. [ 103 ] and Oxman et al. [ 114 ] found them equally unimportant for depression outcomes.

There also seems to be no consensus regarding gender differences in the association of network size and depression. While two scholars found a significant association of network size and depression only in women but not men [ 83 , 111 ], three scholars found no evidence for gender differences [ 91 , 104 , 106 ]. Minicuci et al. [ 103 ] found the numbers of relatives with close contacts to only be significantly associated with depression in women but not men, while the number of close contacts was significantly associated with depression in men and women.

Network composition

Network composition was primarily measured by forming network typologies through clustering (see Table  4 ). This method makes it particularly challenging to compare results; however, studies consistently showed that diverse social networks protect against depression compared to more restricted networks [ 120 , 121 , 122 , 123 , 124 , 125 , 126 , 127 , 128 , 129 ]. Concerning network transitions, individuals remaining in and changing to restricted networks showed significantly higher levels of depression than those remaining in non-restricted networks [ 130 , 131 ]. Consistently, Sicotte et al. [ 132 ] found that an increasing diversity of links (measured by diversity of relationship ties) was associated with lower odds of depressive symptoms. Other studies found no significant association [ 105 , 110 ]. When prestige occupation scores were used as a diversity measure, higher diversity was associated with lower levels of depression compared to less diverse networks [ 133 ]. Conversely, Becker et al. [ 83 ] found diverse networks to be less associated with a lack of depressive symptoms compared to those relying solely on their partner as their social network.

Some studies included the share of particular social aspects, such as gender, family, or friends. Consistently, the proportions of females or kin were not identified as significant predictors of depression [ 19 , 100 , 107 , 138 ]. Furthermore, there was no consensus about the composition of family and friends. Social networks primarily consisting of family were found to buffer depression more than networks primarily consisting of friends [ 82 , 87 ]. This was also the case for network transitions [ 140 ]. Conversely, Fiori et al. [ 121 ] found that the absence of family within a friend context was less detrimental than the absence of friends within a family context. Also, Chao [ 109 ] identified that a network proportion of 25–50% family and 50–75% friends was the most advantageous for preventing depression.

While two scholars found no evidence for gender differences in the association of network composition and depression in older adults [ 132 , 136 ], Choi and Jeon [ 120 ] identified gender-specific network types and their association with depression to differ by gender. They found that restricted social network types were associated with increased depressive symptoms in both men and women, whereas a family-centered network was associated with more depressive symptoms only in women.

Contact frequency

Less consistency was found in social interaction frequency’s influence on depression in older adults (see Table  5 ). The cross-sectional studies found 14 significant and 15 insignificant associations. In contrast, among the longitudinal studies, only one significant piece of evidence was found [ 109 ], while six effects were identified as insignificant. Three effects were found to be significant only in certain population groups [ 141 , 142 ]. Furthermore, Blumstein et al. [ 35 ] found a significant negative association between weekly contact with friends and children and depression cross-sectionally; this became insignificant when examined longitudinally. Although cross-sectional results are inconclusive, this could indicate that the frequency of contact has the potential to buffer depression at the time of the event but is not necessarily a sustainable buffer for depression.

There was no consensus among studies about the association of depression with contact frequencies in particular social spheres, such as friends, children, and non-kin [ 35 , 64 , 87 , 97 , 99 , 109 , 141 , 142 , 143 , 144 , 145 , 149 ]. Chi and Chou [ 87 ] found contact frequency with relatives to be more advantageous in buffering depression than the frequency of contact with friends. In contrast, Jeon and Lubben [ 97 ] found contact frequency with non-kin to be negatively associated with depressive symptoms in older Korean immigrants, while contact frequency with kin was not significantly associated.

Only two scholars accounted for gender differences in the association of contact frequency and depression among older adults. Ermer and Proulx [ 91 ] found no significant association of contact frequency and depression in women or men. In their cross-sectional analysis, Blumstein et al. [ 35 ] also found no gender differences in the association between weekly contact with children and depression, but identified weekly contact with friends to only be significantly associated with depression in women but not men. However, these gender differences did not hold longitudinally.

Four articles examined how social network density was associated with depression in older adults (see Table  6 ). The results were inconclusive, cross-sectionally as well as longitudinally. Coleman et al. [ 110 ] and Vicente and Guadalupe [ 107 ] found no significant associations. Furthermore, the significant associations found were contradictory even though the same data and measurements were used. Dorrance Hall et al. [ 90 ] found that confidant network density was negatively associated with levels of depression cross-sectionally. In contrast, Bui [ 19 ] conducted a longitudinal study and found that a higher network density was significantly associated with increased depressive symptoms.

Geographic proximity

Three cross-sectional articles considered geographical proximity as a social network determinant for depression among older adults (see Table  7 ). No study focused on the respective relationship longitudinally. All the articles found significant but inconclusive results. While Litwin et al. [ 102 ] and Vicente and Guadalupe [ 107 ] found that geographically closer social networks buffer depression, Becker et al. [ 83 ] identified that geographically closer social networks increased depression. This may be attributable to the measurement used to assess geographic proximity: Litwin et al. [ 102 ] included individuals living within the respondent’s household, while Becker et al. [ 83 ] did not. This strongly suggests that the direction of effects is dependent on operationalization.

Homogeneity

Furthermore, two cross-sectional studies examined homo-/heterogeneity (see Table  8 ). Their evidence suggested no significant relationship between network homo-/heterogeneity and depression among older adults. Goldberg et al. [ 94 ] determined network homogeneity through questions about the sex, age, and religion of all network members. They found no significant association with depression. Murayama et al. [ 151 ] measured homo-/heterogeneity through respondents’ perceptions of the (dis)similarity of characteristics. They found a significant negative association with depression. This was only found for individuals with a strongly homogenous network and not for those with a weakly homogenous network. No significant relationship was found between network heterogeneity and depression outcomes.

Structural social network variables as outcome variable

Thirteen studies focused on social networks as outcome variables of depression (see Table  9 ). Seven articles examined this association cross-sectionally, while six articles did so longitudinally.

The articles examining the relationship between depression and social networks specifically focused on social network scale outcomes, network size, network composition, density, and contact frequency.

Evidence about the relationship between depression and network scales was mixed. While Merchant et al. [ 154 ] found no evidence cross-sectionally, other scholars found significant evidence that depression was associated with lower scores on network scales [ 37 , 153 , 159 ] and subscales [ 156 ]. However, the longitudinal evidence found was contradictory [ 20 , 36 ].

Depression was primarily identified as a significant predictor for network size. This was found cross-sectionally [ 155 ] and longitudinally [ 19 , 157 , 158 ]. Shouse et al. [ 155 ] found depression to be a predictor for a smaller inner circle network size. Furthermore, Bui [ 19 ] found that depressive symptoms significantly affected an individual’s number of close ties but not total social network size. In contrast, Houtjes et al. [ 157 ] examined differences in network size depending on depression course types. They found decreasing network sizes for all depression course types in older adults.

Cross-sectionally, Ali et al. [ 152 ] found that individuals with more depressive symptoms had smaller and more strained networks. Bui [ 19 ] did not identify depressive symptoms as a significant predictor of the proportion of females in an individual’s network.

No significant evidence suggested that depression affects contact frequency [ 19 , 158 ].

Network density

Bui [ 19 ] did not find depressive symptoms to significantly predict network density.

Reciprocal relationship of structural network aspects and depression

Only five articles examined the relationship between structural network aspects and depression reciprocally [ 19 , 20 , 36 , 37 , 38 ]. However, no reciprocal relationship was found between depression and network size [ 19 , 38 ], composition [ 19 ], contact frequency [ 19 ], and network scales [ 20 , 36 , 37 ]. Bui [ 19 ] only identified greater network density to significantly reduce depressive symptoms 5 years later, but not the other way around. Network size, number of close ties, contact frequency, or network composition did not significantly affect depressive symptoms 5 years later. Furthermore, Domènech-Abella et al. [ 20 ] found that the social network index significantly affects depression longitudinally; however, this relationship was not reciprocal. In contrast, Zhang et al. [ 36 ] found that higher depression scores at baseline predicted lower social network scores at a 6-month follow-up. However, social network scores did not predict depression at a 6-month follow-up. Bui [ 19 ] found more depressive symptoms to be associated with fewer close ties 5 years later. However, all other structural network measures (network size, composition, and contact frequency) were insignificant; therefore, the author concluded that there was no clear reciprocal relationship between structural network measures and depression [ 19 ].

Importance of functional network aspects

Thirty articles included social support in their analysis and examined whether social networks’ structural or functional aspects were more important in predicting depression outcomes in older adults. Singh et al.’s [ 44 ] article was excluded because social support measures’ effect sizes and significance were not presented.

However, no consensus can be reached. Seven studies identified structural aspects as more critical in predicting depression in terms of significant effects [ 35 , 53 , 54 , 74 , 98 , 106 , 117 ], while nine scholars found social support to be more relevant [ 34 , 62 , 82 , 95 , 107 , 108 , 110 , 114 , 129 ]. Sixteen studies found that social support and social network aspects were equally (not) predictive of depressive symptoms [ 19 , 80 , 85 , 86 , 87 , 90 , 92 , 103 , 109 , 118 , 122 , 132 , 133 , 136 , 138 , 142 ].

Social network characteristics and depression among older adults

This study aimed to systematize the evidence about the relationship between social networks and depression in older adults. It focused on the structural aspects of social networks because these are particularly suited for understanding their association with critical health outcomes [ 14 , 15 , 16 ]. It differentiated between the causality of relationships and structural and functional social network characteristics’ impact on depression.

Most articles followed the main-effect model [ 17 ] and considered depression as an outcome variable of social network characteristics in examining the relationship between structural social network aspects and depression among older adults. Only eight articles exclusively accounted for the reversed logic of causality: social network characteristics as an outcome of depression [ 152 , 153 , 154 , 155 , 156 , 157 , 158 , 159 ]. Five out of 127 articles examined the reciprocal relationship between structural social network characteristics and depression [ 19 , 20 , 36 , 37 , 38 ]. However, these articles found no clear reciprocal relationship. Therefore, no theoretical conclusions can be drawn based on these findings.

The majority of articles focused on depression as an outcome of older adults’ social network characteristics. They primarily used cross-sectional evidence. Structural network characteristics were predominantly operationalized through network scales, size, composition, and contact frequency. Conversely, they generally neglected network density, homogeneity, and geographical proximity. Evidence about whether and how the latter three social network aspects affect depression outcomes in older adults was inconsistent [ 19 , 83 , 90 , 94 , 102 , 107 , 110 , 151 ]. Most evidence supported the assumption that higher scores on social network scales buffer depression [ 20 , 37 , 41 , 42 , 43 , 45 , 46 , 47 , 48 , 49 , 50 , 51 , 52 , 53 , 54 , 56 , 57 , 58 , 61 , 63 , 64 , 65 , 66 , 68 , 69 , 70 , 71 , 72 , 74 , 75 , 76 , 79 , 80 , 81 ]. Corroborating previous literature reviews [ 2 , 13 ], some evidence suggested that a more extensive network size buffers depression outcomes in older adults compared to a smaller network size [ 33 , 64 , 78 , 82 , 83 , 85 , 86 , 87 , 90 , 92 , 93 , 94 , 96 , 98 , 99 , 100 , 101 , 102 , 106 , 109 , 112 , 114 , 115 , 117 , 119 ]. Three quarters of the studies also identified that network composition was significantly associated with depression outcomes in older adults; diverse social networks were found to be more beneficial than restricted networks [ 120 , 121 , 122 , 123 , 124 , 125 , 126 , 127 , 128 , 129 , 130 , 131 ]. This aligns with Santini et al.’s [ 13 ] findings, who consistently identified diverse types of social networks as associated with favorable depression outcomes. Results on the effect of contact frequency on depression were less consistent: no clear evidence was found cross-sectionally, and no substantial effects of contact frequency were found in longitudinal studies. This confirms Schwarzbach et al.’s [ 3 ] findings, which reported inconsistent results cross-sectionally and longitudinally.

Furthermore, the effects of social network aspects on depression seem to be largely stable for women and men [ 35 , 43 , 47 , 50 , 60 , 66 , 68 , 80 , 83 , 91 , 103 , 104 , 106 , 111 , 120 , 132 , 136 , 151 ]. Notably, no consensus can be reached about whether family or friends are more critical for favorable depression outcomes in older adults [ 41 , 42 , 43 , 44 , 82 , 87 , 109 , 121 , 140 ]. This challenges the previous assumption that family is the most crucial source of good health [ 160 ].

A minority of articles found social network characteristics to be outcomes of depression. While depression did not influence density [ 19 ] and contact frequency [ 19 , 158 ], an unclear effect was found for network scales [ 20 , 36 , 37 , 153 , 154 , 156 , 159 ] and network composition [ 19 , 152 ]. However, depression significantly reduced the size of an individual’s social network and their number of close relationships [ 19 , 155 , 157 , 158 ].

This review does not confirm the previous systematic reviews’ findings [ 3 , 13 ] that social networks’ functional aspects are more important than their structural aspects in predicting depression. The articles that considered functional network characteristics showed no consensus about whether structural or functional network aspects were more important in buffering depression outcomes in older adults [ 19 , 34 , 35 , 53 , 54 , 62 , 74 , 80 , 82 , 85 , 86 , 87 , 90 , 92 , 95 , 98 , 103 , 106 , 107 , 108 , 109 , 110 , 114 , 117 , 118 , 122 , 129 , 132 , 133 , 136 , 138 , 142 ].

Furthermore, very few studies reported effect sizes. However, the studies that reported standardized coefficients almost exclusively identified small effect sizes across all structural social network aspects [ 41 , 43 , 47 , 51 , 52 , 53 , 54 , 55 , 56 , 58 , 59 , 61 , 63 , 64 , 65 , 66 , 85 , 86 , 87 , 93 , 96 , 99 , 101 , 102 , 104 , 112 , 120 , 121 , 123 , 125 , 126 , 128 , 129 , 133 , 137 , 139 , 140 , 147 , 153 , 159 ]. Although the studies covered a wide sample size range, there were no differences in the results. This suggests that structural network aspects have a rather small but stable influence on depression. However, future studies should report effect sizes (e.g., by standardized coefficients) to ensure the comparability of studies and individual effects.

Limitations and future implications

This systematic review is the first to specifically focus on the relationship between structural social network aspects and depression outcomes among older adults. While previous systematic reviews have been helpful, they have loosely applied the constructs of social networks and limited their focus to particular geographic areas. Additionally, the vast body of evidence that has emerged during the last decade highlights the importance of this updated systematic review. However, our review has some limitations. Like other reviews, the articles included in this review may be prone to publication bias. In addition, we did not use controlled vocabulary terms such as MeSH and Psychological Index Terms in our search strategy. As our search strategy and keywords were informed by other reviews [ 2 , 3 , 5 , 6 , 7 , 8 , 13 , 23 , 24 , 25 ], we used a diverse range of keywords relevant to the field. Our comprehensive search strategy is reflected in the high number of initial articles found. Consequently, we anticipate having identified all relevant articles. Furthermore, we only included articles published in English, neglecting the findings reported in different languages. However, we did this to counteract possible regional bias induced by language knowledge of the authors. Additionally, the exclusion of non-English articles was found to have minimal impact on the results and overall conclusions of a review [ 161 , 162 ]. However, future research could employ machine translation to counteract selection bias induced by language restrictions. This should be particularly beneficial in contexts in which limited evidence exists.

Further, it must be emphasized that we focused on community-dwelling older adults, excluding institutionalized individuals from analysis. It should be acknowledged that regional bias may arise, given the different proportions of older adults living in institutions across countries. However, we decided to do this as institutionalized individuals are likely to have predetermined social networks which may affect depression outcomes differently.

Additionally, the use of the term “social network” may exclude studies focusing solely on family networks, which are highly relevant for the mental health of older adults. However, as the individual network should not be limited to family networks alone, we have deliberately opted for the holistic term here, to capture the social network in its entirety. This approach is supported by the ambiguous results on the importance of family and friendship relationships for depression among older adults (see analysis above).

Furthermore, this systematic review included studies from peer-reviewed journals, excluding gray literature. This may limit our findings. However, it ensures that the included articles are high quality. Furthermore, systematic reviews do not allow qualitative studies to be included. While qualitative studies are limited in their potential to establish causal relationships between variables, they provide valuable insights into the understanding and interpretation of psychosocial phenomena that quantitative research often cannot access.

This systematic review aimed to understand the potential of structural social network characteristics holistically by reviewing them all and not limiting the focus on only a few. That is why we did not conduct a meta-analysis. Firstly, evidence is too small to be statistically analyzed, such as in the social network domains network density, homogeneity, and geographical proximity. Secondly, particularly in the social network domain composition, results are not necessarily comparable since cluster analysis results in different numbers of clusters which are consequently characterized differently. However, future research should conduct a meta-analysis with the more comparable domains network scale, size, and contact frequency.

Despite this review’s limitations, its strength lies in its systematic search; multiple keywords and broad terminologies were used to capture as many articles as possible. This is reflected in the significant number of publications included in this review.

Much of the evidence reported here came from cross-sectional studies. Additionally, only eight of the 127 articles exclusively considered social networks as dependent variables, and only five studies examined the reciprocal relationship. This makes it particularly difficult to draw causal conclusions about the relationship between social networks and depression among older adults. Further research is needed to disentangle the reciprocal relationship using longitudinal data. Furthermore, limited literature focused on the relationship between depression and network density, homogeneity, and geographical proximity. Additionally, these results were inconclusive. Therefore, these relationships should be closely examined in future research.

This review gathered evidence and confirmed that having larger and more diverse social networks and closer ties buffers depression among older adults. Evidence about the relationship between contact frequency and depression was inconclusive. Literature on the relationships between depression and network density, homogeneity, and geographical proximity is scarce and inconclusive; therefore, further research is needed. Although this review examined a vast body of research about the relationship between social network aspects and depression among older adults, no conclusions about causality could be drawn. Contrary to other reviews, the evidence suggests that functional and structural networks are equally important in determining depression outcomes in older adults.

This review highlights that quantifying older adults’ social relations is crucial to understanding depression outcomes in older adults. As the population ages and multimorbidity and social isolation increase, appropriate social gerontological interventions are needed. Based on this review, interventions could potentially promote the integration of older adults into larger and more diverse social settings. Following the recommendations of a systematic review about the effectiveness of interventions targeting social isolation in older adults [ 163 ], group interventions like social activities are the most effective in broadening older adults’ social networks and increasing their contacts. These interventions can help to counteract depression in older adults.

Availability of data and materials

The datasets used and/or analyzed during the current study are available from the corresponding author on reasonable request. All data generated or analyzed during this study are included in this published article.

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Acknowledgements

We thank Alexander Trinidad for the useful information in the beginning of the article process. We particularly thank Anna Leuwer (AL) for the extraction of the data as quality check. Special thanks to Lea Ellwardt and Karsten Hank for the valuable feedback on earlier versions of this manuscript.

Open Access funding enabled and organized by Projekt DEAL. This work was supported by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) under Grant [454899704].

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Reiner, A., Steinhoff, P. The association of social networks and depression in community-dwelling older adults: a systematic review. Syst Rev 13 , 161 (2024). https://doi.org/10.1186/s13643-024-02581-6

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Exploring the nature of diversity dishonesty within predominantly white schools of medicine, pharmacy, and public health at the most highly selective and highly ranked u.s. universities.

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Burrell, D.N. Exploring the Nature of Diversity Dishonesty within Predominantly White Schools of Medicine, Pharmacy, and Public Health at the Most Highly Selective and Highly Ranked U.S. Universities. Soc. Sci. 2024 , 13 , 332. https://doi.org/10.3390/socsci13070332

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Burrell, Darrell Norman. 2024. "Exploring the Nature of Diversity Dishonesty within Predominantly White Schools of Medicine, Pharmacy, and Public Health at the Most Highly Selective and Highly Ranked U.S. Universities" Social Sciences 13, no. 7: 332. https://doi.org/10.3390/socsci13070332

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The Journal of Social Studies Research

The Journal of Social Studies Research

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  • Aims and Scope
  • Editorial Board
  • Abstracting / Indexing
  • Submission Guidelines

The Journal of Social Studies Research (JSSR) is an internationally recognized peer-reviewed journal designed to foster the dissemination of ideas and research findings related to the social studies. JSSR is the official publication of The International Society for the Social Studies (ISSS). JSSR is published four times a year. 

University of Tennessee, USA
East Tennessee State University, USA
University of South Florida, USA
Kansas State University, USA
Western Oregon University, USA
East Tennessee State University, USA
University of Tennessee, USA
Ankara, Turkey

Manuscript Submission Guidelines: The Journal of Social Studies Research

Please read the guidelines below then visit the Journal’s submission site [ https://mc.manuscriptcentral.com/ssr ] to upload your manuscript. Please note that manuscripts not conforming to these guidelines may be returned. Remember you can log in to the submission site at any time to check on the progress of your paper through the peer review process.

Sage Publishing disseminates high-quality research and engaged scholarship globally, and we are committed to diversity and inclusion in publishing. We encourage submissions from a diverse range of authors from across all countries and backgrounds.

Only manuscripts of sufficient quality that meet the aims and scope of The Journal of Social Studies Research will be reviewed.

There are no fees payable to submit or publish in this Journal. Open Access options are available - see section 3.3 below.

As part of the submission process you will be required to warrant that you are submitting your original work, that you have the rights in the work, and that you have obtained and can supply all necessary permissions for the reproduction of any copyright works not owned by you, that you are submitting the work for first publication in the Journal and that it is not being considered for publication elsewhere and has not already been published elsewhere. Please see our guidelines on prior publication and note that The Journal of Social Studies Research will consider submissions of papers that have been posted on preprint servers; please alert the Editorial Office when submitting (contact details are at the end of these guidelines) and include the DOI for the preprint in the designated field in the manuscript submission system. Authors should not post an updated version of their paper on the preprint server while it is being peer reviewed for possible publication in the Journal. If the article is accepted for publication, the author may re-use their work according to the Journal's author archiving policy.

If your paper is accepted, you must include a link on your preprint to the final version of your paper.

If you have any questions about publishing with Sage, please visit the Sage Journal Solutions Portal .

  • What do we publish? 1.1 Aims & Scope 1.2 Article types 1.3 Writing your paper
  • Editorial policies 2.1 Peer review policy 2.2 Authorship 2.3 Acknowledgements 2.4 Funding 2.5 Declaration of conflicting interests 2.6 Research data
  • Publishing policies 3.1 Publication ethics 3.2 Contributor’s publishing agreement 3.3 Open access and author archiving
  • Preparing your manuscript 4.1 Formatting 4.2 Artwork, figures and other graphics 4.3 Identifiable information 4.4 Supplemental material 4.5 Reference style 4.6 English language editing services
  • Submitting your manuscript 5.1 ORCID 5.2 Information required for completing your submission 5.3 Permissions
  • On acceptance and publication 6.1 Sage Production 6.2 Online First publication 6.3 Access to your published article 6.4 Promoting your article
  • Further information 7.1 Appealing the publication decision

1. What do we publish?

1.1 Aims & Scope

Before submitting your manuscript to The Journal of Social Studies Research, please ensure you have read the Aims & Scope .

1.2 Article types

  • Original Research
  • Book Reviews
  • Media Reviews

Typical submissions range between 20-35 pages not including the title, keywords/ abstract, or references.

There are no limit to the number of references.

1.3 Writing your paper

The Sage Author Gateway has some general advice on how to get published , plus links to further resources.

Sage Author Services also offers authors a variety of ways to improve and enhance your article including English language editing, plagiarism detection, and video abstract and infographic preparation.

1.3.1 Make your article discoverable

For information and guidance on how to make your article more discoverable, visit our Gateway page on How to Help Readers Find Your Article Online .

Back to top

2. Editorial policies

2.1 Peer review policy

Sage does not permit the use of author-suggested (recommended) reviewers at any stage of the submission process, be that through the web-based submission system or other communication.

Reviewers should be experts in their fields and should be able to provide an objective assessment of the manuscript. Our policy is that reviewers should not be assigned to a paper if:

  • The reviewer is based at the same institution as any of the co-authors.
  • The reviewer is based at the funding body of the paper.
  • The author has recommended the reviewer.
  • The reviewer has provided a personal (e.g. Gmail/Yahoo/Hotmail) email account and an institutional email account cannot be found after performing a basic Google search (name, department and institution).

The journal’s policy is to have manuscripts reviewed by two expert reviewers. The Journal of Social Studies Research utilizes a double-anonymized peer review process in which the reviewer and authors’ names and information are withheld from the other. Reviewers may at their own discretion opt to reveal their names to the author in their review but our standard policy practice is for their identities to remain concealed. All manuscripts are reviewed as rapidly as possible, while maintaining rigor. Reviewers make comments to the author and recommendations to the Editor who then makes the final decision.

The Editor or members of the Editorial Board may occasionally submit their own manuscripts for possible publication in the Journal. In these cases, the peer review process will be managed by alternative members of the Board and the submitting Editor/Board member will have no involvement in the decision-making process.

The Journal of Social Studies Research is committed to delivering high quality, fast peer-review for your paper, and as such has partnered with Web of Science (previously Publons). Web of Science is a third-party service that seeks to track, verify and give credit for peer review. Reviewers for The Journal of Social Studies Research can opt in to Web of Science in order to claim their reviews or have them automatically verified and added to their reviewer profile. Reviewers claiming credit for their review will be associated with the relevant journal, but the article name, reviewer’s decision and the content of their review is not published on the site. For more information visit the Web of Science website.

2.2 Authorship

All parties who have made a substantive contribution to the article should be listed as authors. Principal authorship, authorship order, and other publication credits should be based on the relative scientific or professional contributions of the individuals involved, regardless of their status. A student is usually listed as principal author on any multiple-authored publication that substantially derives from the student’s dissertation or thesis.

Please note that AI chatbots, for example ChatGPT, should not be listed as authors. For more information see the policy on Use of ChatGPT and generative AI tools .

2.3 Acknowledgements

All contributors who do not meet the criteria for authorship should be listed in an Acknowledgements section. Examples of those who might be acknowledged include a person who provided purely technical help, or a department chair who provided only general support.

Please supply any personal acknowledgements separately to the main text to facilitate anonymous peer review.

Per ICMJE recommendations , it is best practice to obtain consent from non-author contributors who you are acknowledging in your paper.

2.3.1 Third party submissions

Where an individual who is not listed as an author submits a manuscript on behalf of the author(s), a statement must be included in the Acknowledgements section of the manuscript and in the accompanying cover letter. The statements must:

  • Disclose this type of editorial assistance – including the individual’s name, company and level of input
  • Identify any entities that paid for this assistance
  • Confirm that the listed authors have authorized the submission of their manuscript via third party and approved any statements or declarations, e.g. conflicting interests, funding, etc.

Where appropriate, Sage reserves the right to deny consideration to manuscripts submitted by a third party rather than by the authors themselves.

2.3.2 Writing assistance

Individuals who provided writing assistance, e.g., from a specialist communications company, do not qualify as authors and so should be included in the Acknowledgements section. Authors must disclose any writing assistance – including the individual’s name, company and level of input – and identify the entity that paid for this assistance. It is not necessary to disclose use of language polishing services.

2.4 Funding

The Journal of Social Studies Research requires all authors to acknowledge their funding in a consistent fashion under a separate heading.  Please visit the Funding Acknowledgements page on the Sage Journal Author Gateway to confirm the format of the acknowledgment text in the event of funding, or state that: This research received no specific grant from any funding agency in the public, commercial, or not-for-profit sectors. 

2.5 Declaration of conflicting interests

It is the policy of The Journal of Social Studies Research to require a declaration of conflicting interests from all authors enabling a statement to be carried within the paginated pages of all published articles.

Please ensure that a ‘Declaration of Conflicting Interests’ statement is included at the end of your manuscript, after any acknowledgements and prior to the references. If no conflict exists, please state that ‘The Author(s) declare(s) that there is no conflict of interest’. For guidance on conflict of interest statements, please see the ICMJE recommendations here .

2.6 Research data

The Journal is committed to facilitating openness, transparency and reproducibility of research, and has the following research data sharing policy. For more information, including FAQs please visit the Sage Research Data policy pages .

Subject to appropriate ethical and legal considerations, authors are encouraged to:

  • Share your research data in a relevant public data repository
  • Include a data availability statement linking to your data. If it is not possible to share your data, use the statement to confirm why it cannot be shared.
  • Cite this data in your research

Peer reviewers may be asked to peer review the research data prior to publication.

  • Peer reviewers may be asked to assess compliance with the research data policy
  • Peer reviewers may be asked to assess research data files

If you need to anonymize your research data for peer review, please refer to our Research Data Sharing FAQs for guidance.  

3. Publishing policies

3.1 Publication ethics

Sage is committed to upholding the integrity of the academic record. We encourage authors to refer to the Committee on Publication Ethics’ International Standards for Authors and view the Publication Ethics page on the Sage Author Gateway .

3.1.1 Plagiarism

The Journal of Social Studies Research and Sage take issues of copyright infringement, plagiarism or other breaches of best practice in publication very seriously. We seek to protect the rights of our authors and we always investigate claims of plagiarism or misuse of published articles. Equally, we seek to protect the reputation of the Journal against malpractice. Submitted articles may be checked with duplication-checking software. Where an article, for example, is found to have plagiarized other work or included third-party copyright material without permission or with insufficient acknowledgement, or where the authorship of the article is contested, we reserve the right to take action including, but not limited to: publishing an erratum or corrigendum (correction); retracting the article; taking up the matter with the head of department or dean of the author's institution and/or relevant academic bodies or societies; or taking appropriate legal action.

3.1.2 Prior publication

If material has been previously published it is not generally acceptable for publication in a Sage journal. However, there are certain circumstances where previously published material can be considered for publication. Please refer to the guidance on the Sage Author Gateway or if in doubt, contact the Editor at the address given below.

3.2 Contributor’s publishing agreement

Before publication, Sage requires the author as the rights holder to sign a Journal Contributor’s Publishing Agreement. Sage’s Journal Contributor’s Publishing Agreement is an exclusive license agreement which means that the author retains copyright in the work but grants Sage the sole and exclusive right and license to publish for the full legal term of copyright. Exceptions may exist where an assignment of copyright is required or preferred by a proprietor other than Sage. In this case copyright in the work will be assigned from the author to the society. For more information, please visit the Sage Author Gateway .

3.3 Open access and author archiving

The Journal of Social Studies Research offers optional open access publishing via the Sage Choice programme and Open Access agreements, where authors can publish open access either discounted or free of charge depending on the agreement with Sage. Find out if your institution is participating by visiting Open Access Agreements at Sage . For more information on Open Access publishing options at Sage please visit Sage Open Access . For information on funding body compliance, and depositing your article in repositories, please visit Sage’s Author Archiving and Re-Use Guidelines and Publishing Policies .

4. Preparing your manuscript

4.1 Formatting

The preferred format for your manuscript is Word.

4.2 Artwork, figures and other graphics

For guidance on the preparation of illustrations, pictures and graphs in electronic format, please visit Sage’s Manuscript Submission Guidelines .

4.3 Identifiable information

Where a journal uses double-anonymized peer review, authors are required to submit:

  • A version of the manuscript which has had any information that compromises the anonymity of the author(s) removed or anonymized. This version will be sent to the peer reviewers.
  • A separate title page which includes any removed or anonymized material. This will not be sent to the peer reviewers.

See https://us.sagepub.com/en-us/nam/Manuscript-preparation-for-double-anonymized-journal for detailed guidance on making an anonymous submission.

Figures supplied in color will appear in color online regardless of whether or not these illustrations are reproduced in color in the printed version. For specifically requested color reproduction in print, you will receive information regarding the costs from Sage after receipt of your accepted article.

4.4 Supplemental material

This Journal is able to host additional materials online (e.g., datasets, podcasts, videos, images etc.) alongside the full-text of the article. For more information please refer to our guidelines on submitting supplemental files .

4.5 Reference style

The Journal of Social Studies Research adheres to the APA reference style. View the APA guidelines to ensure your manuscript conforms to this reference style.

4.6 English language editing services

Authors seeking assistance with English language editing, translation, or figure and manuscript formatting to fit the Journal’s specifications should consider using Sage Language Services. Visit Sage Language Services on our Journal Author Gateway for further information.

5. Submitting your manuscript

The Journal of Social Studies Research is hosted on Sage Track, a web based online submission and peer review system powered by ScholarOne™ Manuscripts. Visit [ https://mc.manuscriptcentral.com/ssr ] to login and submit your article online.

IMPORTANT : Please check whether you already have an account in the system before trying to create a new one. If you have reviewed or authored for the Journal in the past year it is likely that you will have had an account created.  For further guidance on submitting your manuscript online please visit ScholarOne Online Help .

As part of our commitment to ensuring an ethical, transparent and fair peer review process Sage is a supporting member of ORCID, the Open Researcher and Contributor ID . ORCID provides a unique and persistent digital identifier that distinguishes researchers from every other researcher, even those who share the same name, and, through integration in key research workflows such as manuscript and grant submission, supports automated linkages between researchers and their professional activities, ensuring that their work is recognized.

The collection of ORCID IDs from corresponding authors is now part of the submission process of this Journal. If you already have an ORCID ID you will be asked to associate that to your submission during the online submission process. We also strongly encourage all co-authors to link their ORCID ID to their accounts in our online peer review platforms. It takes seconds to do: click the link when prompted, sign into your ORCID account and our systems are automatically updated. Your ORCID ID will become part of your accepted publication’s metadata, making your work attributable to you and only you. Your ORCID ID is published with your article so that fellow researchers reading your work can link to your ORCID profile and from there link to your other publications.

If you do not already have an ORCID ID please follow this link to create one or visit our ORCID homepage to learn more.

5.2 Information required for completing your submission

You will be asked to provide contact details and academic affiliations for all co-authors via the submission system and identify who is to be the corresponding author. These details must match what appears on your manuscript. The affiliation listed in the manuscript should be the institution where the research was conducted. If an author has moved to a new institution since completing the research, the new affiliation can be included in a manuscript note at the end of the paper. At this stage please ensure you have included all the required statements and declarations and uploaded any additional supplementary files (including reporting guidelines where relevant).

5.3 Permissions

Please also ensure that you have obtained any necessary permission from copyright holders for reproducing any illustrations, tables, figures or lengthy quotations previously published elsewhere. For further information including guidance on fair dealing for criticism and review, please see the Copyright and Permissions page on the Sage Author Gateway .

6. On acceptance and publication

6.1 Sage Production

Your Sage Production Editor will keep you informed as to your article’s progress throughout the production process. Proofs will be made available to the corresponding author via our editing portal Sage Edit or by email, and corrections should be made directly or notified to us promptly. Authors are reminded to check their proofs carefully to confirm that all author information, including names, affiliations, sequence and contact details are correct, and that Funding and Conflict of Interest statements, if any, are accurate.

6.2 Online First publication

Online First allows final articles (completed and approved articles awaiting assignment to a future issue) to be published online prior to their inclusion in a journal issue, which significantly reduces the lead time between submission and publication. Visit the Sage Journals help page for more details, including how to cite Online First articles.

6.3 Access to your published article

Sage provides authors with online access to their final article.

6.4 Promoting your article

Publication is not the end of the process! You can help disseminate your paper and ensure it is as widely read and cited as possible. The Sage Author Gateway has numerous resources to help you promote your work. Visit the Promote Your Article page on the Gateway for tips and advice.

7. Further information

Any correspondence, queries or additional requests for information on the manuscript submission process should be sent to The Journal of Social Studies Research editorial office as follows:

[email protected] and [email protected]

7.1 Appealing the publication decision

Editors have very broad discretion in determining whether an article is an appropriate fit for their journal. Many manuscripts are declined with a very general statement of the rejection decision. These decisions are not eligible for formal appeal unless the author believes the decision to reject the manuscript was based on an error in the review of the article, in which case the author may appeal the decision by providing the Editor with a detailed written description of the error they believe occurred.

If an author believes the decision regarding their manuscript was affected by a publication ethics breach, the author may contact the publisher with a detailed written description of their concern, and information supporting the concern, at [email protected] .

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New research highlights where 'The Big One' earthquake could hit

Northern part of the long pacific ocean fault most likely to produce a major earthquake, scientists say.

research review journal of social science

Social Sharing

New research offers a clearer picture of a fault line hundreds of kilometres long off the West Coast that is predicted to generate a major earthquake and tsunami commonly known as "The Big One."

The study confirms that the northern part of the fault, close to Vancouver Island and Washington state, is most likely to produce a major earthquake. 

"It's giving us the first really detailed look at this huge megathrust fault that we've long known about but haven't had any details about," Edwin Nissen, a University of Victoria earth and ocean science researcher who was not involved in the research into the fault line where two tectonic plates meet.

The research, recently published in the prestigious journal Science Advances, produced the most detailed picture researchers have yet had of the fault zone spanning more than 900 kilometres from northern California to Vancouver Island — imaging they say helps them understand the magnitude and probability of earthquakes. 

research review journal of social science

Clearer picture of B.C.’s ‘big one’ emerges — and it’s not good

Subduction zones are regions where two tectonic plates collide — one plate sliding under the other toward the Earth's mantle.

In the Cascadia Subduction Zone, the Juan de Fuca tectonic plate is slowly sliding underneath the North American plate.

Most of the time, the plates are locked in place, pushing against each other and building stress. Once every several hundred years or so, they generate a  major megathrust earthquake  and large tsunami. 

According to Suzanne Carbotte, the study's lead author and Columbia University marine geophysicist, many subduction zones produce small earthquakes. These help researchers understand the faults and fragmentations deep in the Earth. However, in the Cascadia zone, where these earthquakes aren't common, researchers didn't have that information. 

A woman with grey hair smiles.

About 50 researchers and crew took to the water on a ship that traced the Cascadia fault line. The ship was equipped with sophisticated imaging technology, which Nissen said is usually used by oil and gas companies for exploration. 

"Most academic scientists don't have the kind of money these companies have," Nissen said. "To get this kind of data for a purely scientific purpose is really exciting."

Researchers sent low-frequency sound pulses into the fault. A 15-kilometre-long receiver, towed behind the boat equipped with hydrophones, picked up the resulting echoes. With this information, researchers created high-resolution images.

research review journal of social science

Earthquakes: "The Big One" is coming

They found the surface where the Juan de Fuca and North American plates interlock is much more complex and jagged than they had previously mapped.

Kelin Wang, a researcher with the Geological Survey of Canada and adjunct professor at the University of Victoria who was not involved in the research, said a survey of this scale hasn't been conducted before. 

He said it helps explain historical earthquakes near the northern Pacific Ocean, such as the one  that hit North America and the resulting tsunami that reached Japan in 1700. 

"In a couple of years, we'll know a lot more about this system if we begin to model earthquakes and incorporate this information," he said.

  • How Metro Vancouver is earthquake-proofing its water reservoirs in preparation for the 'Big One'
  • Earthquake 'swarm' strikes off B.C. coast, but no sign of the 'Big One'

While it's not possible to actually predict earthquakes, Carbotte said the information will help hazard-researchers understand the probabilities of earthquakes and tsunamis. Those models can inform building codes and tsunami evacuation plans to protect coastal populations. 

"The probabilities are high that we're going to see a megathrust earthquake in the [Pacific Northwest] in the next 100 years," Carbotte said. "[This research] does very much inform the hazard and resilience mitigation efforts."

ABOUT THE AUTHOR

research review journal of social science

Reporter/Editor

Isaac Phan Nay is a CBC News reporter/editor in Vancouver. Please contact him at [email protected].

With files from Lyndsay Duncombe

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How to Vet Information Before Making a Decision

  • Alex Edmans

research review journal of social science

Four questions to ask when you’re considering the evidence.

The daily decisions modern leaders face are increasingly complex. But executives have a tool to combat these challenges – information. At the click of a mouse or the press of a thumb, they can call up cutting edge research on virtually any topic. With so much information available, how do we know what to trust? What executives need is a simple taxonomy of misinformation so they know what to look out for. Drawing on the tools of social science research we can categorize misinformation into four missteps. This framework can be useful to leaders of all kinds who need to ask better questions to manage their own information onslaughts.

The challenges facing business leaders have never been greater. Regular decisions are increasingly complex, given inflation, trade tensions, and political uncertainty. Human capital issues now include diversity, equity and inclusion, mental health, and upskilling for the fourth industrial revolution. Environmental, social and governance concerns can no longer be delegated to a corporate social responsibility department; they’re the duty of the C-suite. Artificial intelligence brings myriad new opportunities, but also multiple new threats.

research review journal of social science

  • Alex Edmans is a Professor of Finance at London Business School, where he specializes in corporate finance, behavioral finance, and corporate social responsibility. He earned his BA from Oxford University and his Ph.D. from MIT, where he was a Fulbright scholar. He is the author of May Contain Lies: How Stories, Statistics, and Studies Exploit Our Biases – And What We Can Do About It (Penguin Random House, 2024).

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Reimagining insect research: Interview with Roel van Klink and Leandro Nascimento

  • Three out of every four known species on Earth are insects, but efforts to monitor, study and protect them have been lagging worldwide.
  • A new themed issue published in the journal Philosophical Transactions of the Royal Society delves into four tech tools that have the ability to reshape insect research in the coming years.
  • The issue highlights acoustic monitoring, remote sensing using radars, computer vision, and DNA sequencing as potential tools that could help scientists and researchers ramp up global insect biodiversity monitoring.

They might comprise close to 75% of all known animal species. But when it comes to the monitoring and protection of insects, global efforts have been inadequate.

The numbers tell a harrowing story.

A global review of insect populations published in 2019 in the journal Biological Conservation found that 40% of insect species are threatened with extinction, which could lead to “a catastrophic collapse” of ecosystems worldwide.

“Most insects are relatively uninteresting for humans,” Roel van Klink, senior researcher at the Biodiversity Synthesis Research Group at the German Centre for Integrative Biodiversity Research, told Mongabay in a video interview. “It’s very laborious work, and society has not been willing to pay for the time that it actually needs to do this well.”

Even as technology is being increasingly deployed to study and monitor insects globally, van Klink said he realized that groups developing these tools were often unaware of developments in other spheres. “It seemed that they were not talking to each other,” he said. “There were parallel developments in different countries.”

As a first step toward addressing this concern and to get people to collaborate, van Klink brought together a group of scientists, researchers and technologists working on insect biodiversity. Working with them, he and a team collected, compiled and edited a special issue of studies titled “ Towards a toolkit for global insect biodiversity monitoring ” that was published in the journal Philosophical Transactions of the Royal Society .

The issue comprises research from 142 authors in 27 countries with a focus on four cutting-edge technological developments that could potentially reshape insect biodiversity monitoring in the years ahead. They include acoustic monitoring to identify insects from sound; computer vision to identify them from images; radar technology to detect insects remotely; and the use of DNA to identify species.

An insect on a white flower.

Roel van Klink spoke with Mongabay’s Abhishyant Kidangoor about the state of global insect biodiversity monitoring and how technology might help fill the gaps. He was also joined by bioacoustics scientist Leandro Nascimento, who was part of the editorial team for the special issue. This interview has been edited for length and clarity.

Mongabay: How is insect biodiversity monitoring faring globally?

Roel van Klink: The status is actually really bad. It’s all being done with traditional methods, which means you need to catch the insects and then you need to identify and count morphologically. Everything is done manually. Most of that is done in Europe. We have a very long tradition going back to maybe the 1920s. In the U.S., too, they’ve been doing that for a very long time. But it’s usually for very specific groups of insects. For example, we have a good network for butterfly counting that’s well established in Europe, but there are still European countries that don’t have it. Even in the best case, it goes back only to the ’70s. But again, it’s only for butterflies. In the U.S., they have been measuring mosquitoes going back to the ’60s, but that’s only mosquitoes. Everything else is just random depending on whether there was a person that was willing to or interested in identifying one specific group of insects at one place.

Eventually, the situation is that we may be monitoring only ground beetles in one place, butterflies in another place and mosquitoes in another. And that’s for only some countries. Most of the rest of the world, there’s just almost nothing. It’s really bad for most groups of insects. We don’t even know how they’re doing. We don’t even know which species there are in the tropics.

Mongabay: Why is it this way?

Roel van Klink: Most insects are relatively uninteresting for humans. We can do pest monitoring or disease vector monitoring, and track butterflies, because they’re easy. You can get lots of people to do it. But for all the other obscure little flies and wasps that are out there, it’s very hard even to identify them. For specialists, the literature is huge. There are so many species. Most species have not been described, and it is very laborious work. Society has not been willing to pay for the time that it actually needs to do this well.

Mongabay: What are the gaps in the traditional methods of monitoring and studying insects?

Roel van Klink: The usual methods to catch insects would be something like pitfall trapping. In that, you will only catch the stuff that’s walking on the ground surface and can fall into the trap. If you want to catch flying insects, you will do that with a different method. For example, with a net Malaise trap. Everything that flies in goes up, and there they get caught. If you want to get stuff below the ground, there are different methods that you need. If you want to get insects in vegetation, you would need different methods. Every group of insects needs a different way of getting them.

And then you need so much specialist knowledge to identify all those species because you have a large group to choose from. Here in Germany, for example, we have 33,000 species. Nobody knows all of them. It’s impossible. The people that have most species knowledge can maybe identify 4,000 beetle species. That seems to be really the maximum. If you go to tropical countries, the diversity is even larger. So you have to specialize in one specific group to identify, and therefore you cannot get everything identified. Therefore, for most of the things, we just don’t know what it is.

That’s where these modern methods can help us to monitor many more species, because artificial intelligence essentially can learn unlimited amounts of species in contrast to a human. We can use these methods to identify more species for more locations over longer time periods with much less human effort.

A giraffe weevil in Madagascar.

Leandro Nascimento: If monitored more efficiently, we don’t need to be sending people all the time to the field to collect these animals and to kill them. That’s another problem some people are starting to discuss. Most of these traditional methods are lethal. That means you kill insects. And, who knows, maybe you are capturing an insect that is already endangered or is at risk of extinction. With these other technologies, you don’t necessarily have to kill them. For example, in acoustic monitoring, we’ll be recording the sound passively without killing them. That’s another big advantage.

Mongabay: What was the spark for getting this issue on global insect biodiversity monitoring together?

Roel van Klink: We started this coming from a working group. Me and a colleague had been working on traditional insect monitoring data for quite a while, and we were noticing that lots of different groups of people were trying to develop these modern methods. But it seemed that they were not talking to each other. There were parallel developments in different countries. Radars were being developed. There was acoustics being developed better and better. Then there was the molecular stuff in its own right. We figured we needed to get all these people to start talking to each other. So we organized a workshop in 2021. It had to be virtual, but it was quite well-attended.

Then, in 2022, we could finally do an in-person workshop. That’s where the idea came up to do this as a special issue. We had a very interdisciplinary group. We have ecologists, but we also have computer-vision experts, laser physicists and geneticists. You can do this only in an interdisciplinary manner because of the specialized knowledge that you need, both on insects and the methodology. No one person can do all of that.

Leandro Nascimento: I was called in because my expertise is in bioacoustics. I was working in acoustics for over 10 years. I realized that most of the people working in bioacoustics didn’t have the tools to monitor insects, like training data. They were using bioacoustics and doing mostly classification of birds and mammals, but the insects were again being neglected. In places like the Amazon, India and most tropical countries, insects are the most biodiverse group. Even if you just walk in the forest, you hear all these sounds. We might be recording their sounds, but why are we not studying them? Why are we not classifying them and trying to collect data on them? That was the main motivation for me.

Mongabay: Could you tell me the types of technology that interested you and why you thought they were worth mentioning in your issue?

Roel van Klink: These were the four technologies we started with because they are the best developed. Since then, only two have really started to become established. But these four are the ones that have probably the biggest potential and the widest application. They have different strengths and weaknesses.

With molecular methods, you can probably get the best data on the species identity, but you cannot really get reliable estimates of how many individuals there were in your sample or any environment. But it’s becoming quite an established method. Lots of people are working on it, with barcoding and meta barcoding. And now it has even become possible to do large-scale individual-level barcoding. All of these are established.

The only ones that are really quite new are the lidar stuff. So it’s a laser that gives you very detailed information about anything flying through the laser. We have only very little about that in this issue because it’s fairly new and very few people are working on it.

The use of substrate vibrations is also relatively new. It is the sound that insects make when they knock on wood, or they are gnawing inside the wood or in a plant or in the soil. So it’s related to acoustics in some way. But you need very specific machinery to detect these signals, either with a laser or with the microphone.

Passive acoustic monitoring and image identification using computer vision are tools that are being increasingly used to study insects.

Leandro Nascimento: That’s right. Vibration is quite new. But so is everything else about the hardware. For tracking animals, for example, visually, the way we do for large species is by using camera traps. But we cannot use a camera that is activated by motion sensors to study insects. They’re too tiny for that. So people have been developing new hardware to try to identify insects. And that brings a whole new set of challenges. For visual identification, software is more advanced than hardware.

Roel van Klink: Yeah, software is working quite well. For example, all these apps for identifying stuff like iNaturalist and other observation apps, they work amazingly well with a picture of one insect. If you have enough training data, it works really well. But if you really want a standardized sample of insects, and you need to attract them in some way to a screen with light or a yellow screen and then take a photo of them, that hardware is still being developed. People have been working on it for years, but it’s a slow process. And, basically, you start from scratch because nobody has ever done anything like that before. It’s happening and, hopefully, in a few years, we will have something that can really do this well.

Leandro Nascimento: You can deploy it, for example, in large-scale monitoring programs. The molecular methods, the acoustic methods and even the lidar, you have national-level programs where people are trying to monitor or count insects. But with just camera traps for insects, that’s not still not at that level yet even though the software is quite well developed for recognizing patterns and visual identification.

Roel van Klink: As for the other methods that we cover, radar is quite well developed. And we’ve known actually for a very long time that a radar can detect insects. They did that in the U.K. for a very long time starting in the ’90s. There were some good papers coming out and now there is actually a radar network that can detect anything flying through the beam. But because the radar waves are relatively long, you do not get a whole lot of detail on the organism flying through the beam. And whenever there’s a bird flying through your beam, it gives such a bright signal that everything else cannot be seen anymore. It’s a very interesting method, and it needs more development to really get more information about the insects flying through the beam. But at least there is a network. There are probably 20 radars deployed in Europe now.

In the U.S., they’re working a lot on the weather radar systems. These are horizontal radars that try to capture the rainfall and stuff. They will also detect insects, but that wavelength is even bigger. So the resolution of what you get is much coarser and you can probably only detect the biggest insects. But it covers such a large area that it becomes very interesting because it can measure at places where we have no data. And so that’s why we believe that the combination of all of these different methods gives us the best overview of what’s happening to insects.

A black and red insect.

Mongabay: How can we better bring all these tools together and make them work seamlessly?

Roel van Klink: What we are hoping for is to maybe establish a network of sensors. But then, we do need to get good sensors first. The computer-vision stuff will be absolutely crucial to have. And then what we hope is that we can combine the observations at the ground level from the camera traps and the molecular data with what we observe higher in the sky using the radar, and maybe there will be a lidar in between. Eventually, we hope to scale it up.

What we need to know is how the information is related between all of these different strata. If you have all these different sensors and stations that are local, and you have at the same time the radar going above it at a very high level, then what we hope is that we can extrapolate what we detect at the local level. From that, we hope that the radar detects things where we do not have stations by extrapolating down to what’s happening there. But first, we need proof of principle that these methods can be combined, and more details on what information is being transported between the different levels.

Mongabay: How are you planning to get that moving?

Roel van Klink: What we are hoping to do is get some money to do this. We have a very international team of people. Even in Europe, this is not easy. We have European grants that can work internationally, but they’re extremely competitive. Most of the grants that you can actually get are at the national level. We can maybe get national funding in Germany for developing computer-vision traps. But if we want the best acoustic experts, then we probably need two people from France because the French have developed their methods especially for bush crickets in France. The best radar people are located in Switzerland. The amount of money you need and having all these different countries involved is very challenging. And it’s not straightforward to get funding for all of these different institutes.

Leandro Nascimento: Especially if it is purely for research. I think companies in the private sector can also play a role in getting the fund because then you can get funding not only from the government agencies, but also from private sector investors to try to invest in these technologies. Because many of them are working with these different technologies to get an overall biodiversity assessment of the area. It’s just that they use the technology in isolation and so they’re not combining it. Either they are doing acoustic monitoring, or they’re doing some molecular monitoring, or just using traditional methods, but then not combining them. I also think that the traditional methods are always going to be necessary to describe new species to do the taxonomy work, but it can be integrated with these newer technologies.

I have a lot of taxonomist friends working in Brazil. When they go to collect new species or describe a new species, they don’t take, for example, recorders because it’s not part of their agenda. But why not also record these animals so we can have a reference library of how those animals sound? Then people across science can train machines based on that data.

Roel van Klink: This library issue is really, really important. It’s not just for the acoustics, but also for computer vision, which does not have enough images. You cannot take a machine that was trained in Denmark and put it to use even in Switzerland, let alone in a tropical country. So you’re going to need local experts to identify what the species are. And then you need to have enough photos or sounds to actually train the classifier. This is the challenging part.

For radar and lidar, we probably just have to accept that we’re not going to know everything. Whereas for acoustics, we can get really far in associating a sound with a species. Since we still have 80% of the species on Earth undescribed, it’s going to be a lot of work to also record the sounds of these things as they get described.

What we actually need is a large campaign. There have been big campaigns to record all the DNA sequences of all the species. We’re making progress in that field, but the same should be done for sounds and images so that we can actually start using AI to recognize all these things.

Banner image: A dragonfly perched on a leaf in Thailand. Image by Andre Mouton via Pexels (Public domain).

Abhishyant Kidangoor  is a staff writer at Mongabay. Find him on 𝕏   @AbhishyantPK .

Bioacoustics in your backyard: Q&A with conservation technologist Topher White

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Research & Reviews: Journal of Social Sciences

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Published on 25.6.2024 in Vol 13 (2024)

Social Factors Associated With Nutrition Risk in Community-Dwelling Older Adults in High-Income Countries: Protocol for a Scoping Review

Authors of this article:

Author Orcid Image

  • Christine Marie Mills 1, 2 , BASc, MPH, PhD   ; 
  • Liza Boyar 2 , BASc, MHSc   ; 
  • Jessica A O’Flaherty 3 , BScFN   ; 
  • Heather H Keller 1, 4 , BASc, MSc, PhD  

1 Department of Kinesiology and Health Sciences, University of Waterloo, Waterloo, ON, Canada

2 School of Public Health Sciences, University of Waterloo, Waterloo, ON, Canada

3 Mount Saint Vincent University, Halifax, NS, Canada

4 Schlegel-UW Research Institute for Aging, Waterloo, ON, Canada

Corresponding Author:

Christine Marie Mills, BASc, MPH, PhD

Department of Kinesiology and Health Sciences

University of Waterloo

200 University Avenue West

Waterloo, ON, N2L 3G1

Phone: 1 5198884567

Email: [email protected]

Background: In high-income countries (HICs), between 65% and 70% of community-dwelling adults aged 65 and older are at high nutrition risk. Nutrition risk is the risk of poor dietary intake and nutritional status. Consequences of high nutrition risk include frailty, hospitalization, death, and reduced quality of life. Social factors (such as social support and commensality) are known to influence eating behavior in later life; however, to the authors’ knowledge, no reviews have been conducted examining how these social factors are associated with nutrition risk specifically.

Objective: The objective of this scoping review is to understand the extent and type of evidence concerning the relationship between social factors and nutrition risk among community-dwelling older adults in HICs and to identify social interventions that address nutrition risk in community-dwelling older adults in HICs.

Methods: This review will follow the scoping review methodology as outlined by the JBI Manual for Evidence Synthesis and the PRISMA-ScR (Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews) guidelines. The search will include MEDLINE (Ovid), CINAHL, PsycINFO, and Web of Science. There will be no date limits placed on the search. However, only resources available in English will be included. EndNote (Clarivate Analytics) and Covidence (Veritas Health Innovation Ltd) will be used for reference management and removal of duplicate studies. Articles will be screened, and data will be extracted by at least 2 independent reviewers using Covidence. Data to be extracted will include study characteristics (country, methods, aims, design, and dates), participant characteristics (population description, inclusion and exclusion criteria, recruitment method, total number of participants, and demographics), how nutrition risk was measured (including the tool used to measure nutrition risk), social factors or interventions examined (including how these were measured or determined), the relationship between nutrition risk and the social factors examined, and the details of social interventions designed to address nutrition risk.

Results: The scoping review was started in October 2023 and will be finalized by August 2024. The findings will describe the social factors commonly examined in the nutrition risk literature, the relationship between these social factors and nutrition risk, the social factors that have an impact on nutrition risk, and social interventions designed to address nutrition risk. The results of the extracted data will be presented in the form of a narrative summary with accompanying tables.

Conclusions: Given the high prevalence of nutrition risk in community-dwelling older adults in HICs and the negative consequences of nutrition risk, it is essential to understand the social factors associated with nutrition risk. The results of the review are anticipated to aid in identifying individuals who should be screened proactively for nutrition risk and inform programs, policies, and interventions designed to reduce the prevalence of nutrition risk.

International Registered Report Identifier (IRRID): DERR1-10.2196/56714

Introduction

In high-income countries (HICs), between 65% and 70% of community-dwelling adults aged 65 years and older are at high nutrition risk [ 1 ]. In Canada, one-third of community-dwelling adults aged 60 and older are at increased nutrition risk [ 2 , 3 ]. While there is no universally agreed-upon definition of nutrition risk, 1 common definition is the risk of poor dietary intake and nutritional status [ 3 , 4 ]. Nutrition risk occurs when there are factors present that negatively affect food intake [ 5 ], and can lead to malnutrition if its causes are not addressed [ 3 ].

Many measures or instruments, commonly referred to as tools, are available to measure and screen for nutrition risk and malnutrition risk in community-dwelling older adults, such as Seniors in the Community Risk Evaluation for Eating and Nutrition and the Mini Nutritional Assessment [ 6 ]. Nutrition risk and malnutrition risk lie on a continuum between nutritional health and malnutrition [ 3 ]. Malnutrition is a clinical condition that occurs when there is unintentional weight loss, low body mass index, or reduced muscle mass, along with reduced food intake, reduced assimilation of food and nutrients, chronic disease, or inflammation related to acute disease or injury [ 7 ]. Malnutrition risk exists in clinical settings when individuals have 1 or more of these indicators [ 8 ]. In contrast, nutrition risk occurs earlier in the process. Nutrition risk “represents the determinants and risk factors that place an individual at risk for poor food intake and if not interrupted, can lead to malnutrition” [ 8 ]. However, in the literature, the terms nutrition risk and malnutrition risk are often used interchangeably, with nutrition risk sometimes referred to as early-stage malnutrition risk [ 9 ]. The following figure, adapted from Keller [ 8 ], illustrates the relationship between food intake, nutrition risk, and malnutrition ( Figure 1 ).

research review journal of social science

Individuals who are at nutrition risk are more likely to be hospitalized and have an increased risk of mortality, even when health status, health behaviors, and socioeconomic factors are considered [ 10 , 11 ]. Nutrition risk is also associated with early institutionalization [ 12 ], frailty [ 13 ], and poor quality of life [ 14 , 15 ].

Many social factors are associated with nutrition risk in older adults in the literature [ 16 , 17 ]. These include, but are not limited to, social network type (restricted, diverse, family-focused, friend-focused, etc), living arrangement (alone or with others), social support (emotional, informational, tangible, and affectionate support), social engagement (engagement in social activities with others), and social participation (participation in community activities) [ 3 , 17 - 19 ]. It is well-established that eating with others improves dietary intake and reduces nutrition risk [ 16 ], whereas eating alone is associated with high nutrition risk [ 16 , 20 ]. In many studies, social isolation is a significant factor leading to increased nutrition risk [ 3 , 11 ]. Social relationships may decrease nutrition risk by encouraging compliance with dietary norms [ 16 ], while eating with others may provide “social cues for when and what to eat” [ 16 ]. An individual’s social support system may also encourage healthy behaviors, such as consuming adequate amounts of nutrient-rich foods [ 21 ]. Studies have found that social support helps reduce nutrition risk [ 17 ], whereas low levels of social support are associated with increased nutrition risk [ 22 ]. Individuals with higher levels of social support may have greater assistance with food-related activities, such as meal preparation and grocery shopping [ 16 ]. Social interventions, such as congregate meal programs, have also been shown to improve nutrition risk scores in older adults. Despite the research showing that social factors are associated with nutrition risk, reviews in this area have not specifically focused on nutrition risk, but rather on eating behavior [ 16 ], dietary intake [ 23 ], food choice [ 24 ], or nutrition screening [ 25 ]. Although related to these concepts, nutrition risk is different, describing the presence of risk factors and determinants of food intake such as poor appetite, food insecurity, and low dietary intake [ 14 , 26 ].

To advance research on how social factors are associated with nutrition risk, it is essential to synthesize the available evidence. A scoping review was chosen as it is an appropriate method to understand and summarize the extent and type of evidence available [ 27 ]. It is important to understand the social factors associated with nutrition risk so that individuals who should be screened proactively for nutrition risk can be identified, and programs and policies designed to reduce the prevalence of nutrition risk can be appropriately developed and implemented. Understanding what types of social interventions have been shown to reduce the prevalence of nutrition risk can also help inform such policy and program development.

This review aims to examine the social factors associated with nutrition risk in community-dwelling older adults in HICs and to identify social interventions designed to address nutrition risk in community-dwelling older adults in HICs. A preliminary search was conducted in October 2023 to identify any existing systemic or scoping reviews on this topic. Searching PROSPERO, MEDLINE (Ovid), the Cochrane Database of Systematic Reviews, and JBI Evidence Synthesis identified no current or in-progress scoping reviews or systematic reviews on the topic. There have been reviews examining adjacent topics, for example, the social influences on eating behavior in later life [ 16 ], factors influencing food choice in older adults [ 24 ], and determinants of dietary intake in older people [ 23 ] although none of these have specifically examined the relationship between nutrition risk and social factors or examined social interventions designed to address nutrition risk.

The results of this scoping review will provide researchers and clinicians with knowledge of the social factors associated with nutrition risk in community-dwelling older adults in HICs. Identifying the social factors associated with nutrition risk can help inform future research into nutrition risk and guide program and policy development. Promising social interventions that can improve nutrition risk may also be identified. Additionally, the results of this review may help identify groups of individuals who should be screened for nutrition risk.

Scoping Review Methodology

The proposed scoping review will be conducted in accordance with the JBI methodology for scoping reviews [ 28 ] and in line with the PRISMA-ScR (Preferred Reporting Items for Systematic Reviews and Meta-analyses extension for Scoping Reviews) [ 29 ] .

Research Questions

The research questions for this scoping review are as follows: (1) What social factors (including, but not limited to, social networks, social engagement, social support, and social participation) are associated with nutrition risk or malnutrition risk among community-dwelling adults aged 60 years and older living in HICs? (2) What social interventions improve nutrition risk or malnutrition risk in community-dwelling adults aged 60 years and older living in HICs?

Search Strategy

The search strategy was developed with the assistance of a university research librarian and will be conducted electronically. The search will aim to locate both published and unpublished studies and reviews. An initial limited search of MEDLINE and CINAHL was undertaken to identify articles on the topic. The initial search terms included “malnutrition,” “nutrition risk,” “older adults,” “social factors,” “social support,” “social engagement,” “social participation,” “social influence,” and “social networks.” The text words contained in the titles and abstracts of relevant articles and the index terms used to describe the articles were used to develop a full search strategy for MEDLINE, CINAHL, PsycINFO, and Web of Science. A sample search strategy for MEDLINE is available in Table 1 .

SearchQueryRecords retrieved, n
#1exp Malnutrition/ or exp Nutritional Status/ or nutrition risk.mp.167,909
#2undernutrition.mp.8345
#3poor dietary intake.mp.227
#4poor nutrition.mp. or exp Diet/305,502
#51 or 2 or 3 or 4:453,221
#6exp Aged/ or exp Aging/ or older adults.mp.3,506,670
#7seniors.mp.8211
#8elderly.mp.277,535
#96 or 7 or 8:3,574,189
#10social factors.mp. or exp Social Factors/11,115
#11social support.mp. or exp Social Support/98,186
#12social engagement.mp. or exp Social Participation/4565
#13social influence.mp. or exp Social Behavior/276,421
#14social networks.mp. or exp Social Networking/14,147
#1510 or 11 or 12 or 13 or 14:383,726
#165 and 9 and 15:874

The search strategy, including all identified keywords and index terms, will be adapted for each included database or information source. The reference lists of articles included in the review will be screened for additional studies. Only studies in the English language will be included, as there are limits to language proficiency within the research team. No date restrictions will be applied when conducting searches. As recommended by a research librarian, sources of unpublished studies or gray literature will be searched, including preprint servers such as medRxiv, ProQuest dissertations and theses, Open Grey, and Google Scholar. Both social factors associated with nutrition risk and social interventions designed to address nutrition risk will be searched for in the gray literature.

Study Selection

Inclusion and exclusion criteria have been developed according to the domains of participants, concept, context, and types of evidence sources, as recommended in the JBI Manual for Evidence Synthesis [ 28 ]. The inclusion and exclusion criteria ( Textbox 1 ) are described in detail.

Inclusion criteria

  • Older adults (60 years of age and older)
  • Community-dwelling
  • High-income countries
  • Social factors including social support, social engagement, social participation, social isolation, social inclusion, commensality (eating with others), and loneliness
  • Social interventions such as congregate meals programs, group nutrition education programs, etc
  • Nutrition risk, malnutrition risk, and risk of malnutrition

Exclusion criteria

  • Age groups other than older adults (unless information for older adults available separately)
  • Long-term care, care homes, hospital, institutionalized, and assisted living
  • Low- or middle-income countries
  • No social factors in relation to nutrition risk
  • Not a social intervention
  • Other nutritional factors such as risk of overnutrition, disease-related malnutrition, diet quality, diet patterns, nutrition risk in specific diseases (ie, diabetes, heart disease, kidney disease, dementia, cancer, and COVID-19)

Inclusion Criteria

Participants

This review will consider studies that include community-dwelling adults aged 60 years and older in HICs. The minimum participant age of 60 years is consistent with the United Nations’ definition of older persons [ 30 , 31 ]. Studies that include other age groups but present the results of adults aged 60 years and older as a subgroup will be included, whereas studies that do not separate this age group will not be included, as the causes of nutrition risk may differ in younger age groups. Similarly, studies that examine disease-related nutrition risk and malnutrition risk will be excluded from this review, as specific diseases affect nutrition risk and malnutrition risk in different ways.

This review will be restricted to HICs, given that there is a paucity of literature examining nutrition status specifically in older adults living in low- and middle-income countries (LMICs) [ 32 ], and that the causes of nutrition risk are likely different in LMICs compared with HICs [ 33 ]. In LMICs, food insecurity and rapid urbanization are the major contributors to malnutrition in older adults [ 32 ], and access to sufficient health care and welfare may not be adequate [ 34 ]. Moreover, adherence to the use of validated malnutrition risk screening and assessment tools is low in LMICs, rendering the prevalence of nutrition risk among older adults in these settings largely unquantified [ 32 ].

This review will consider studies that explore nutrition risk and malnutrition risk, in the community. While there is no universally agreed-upon definition of nutrition risk or malnutrition risk, 1 common definition is the risk of poor dietary intake and nutritional status that places an individual at risk of developing malnutrition if action is not taken to improve dietary intake [ 3 , 4 ]. Nutrition risk occurs when there are factors present that negatively affect food intake or nutrient metabolism [ 5 ].

This review will consider studies that examine social factors and social interventions. Social factors include, but are not limited to, social support, social networks, social engagement, and social participation. Social networks are “the web of social relationships that surround an individual and the characteristics of those ties” [ 35 ]. Social participation refers to participation in activities with friends and family or the community [ 36 ], whereas social engagement emphasizes meaningful engagement and desire for social change [ 37 ]. Social support includes “the functions that individuals in a person’s social network perform” [ 36 ]. The term “social factors” can be said to encompass these concepts.

Types of Evidence Sources

This scoping review will consider both experimental and quasi-experimental study designs, including randomized controlled trials that examine how social factors or social interventions affect nutrition risk, nonrandomized controlled trials, before and after studies, and interrupted time-series studies. In addition, analytical observational studies, including prospective and retrospective cohort studies, case-control studies, and analytical cross-sectional studies, will be considered for inclusion. This review will also consider descriptive observational study designs including case series, individual case reports, and descriptive cross-sectional studies for inclusion.

Qualitative studies will also be considered, including, but not limited to, designs such as phenomenology, grounded theory, ethnography, qualitative description, action research, and feminist research. In addition, systematic reviews, rapid reviews, and narrative reviews will be considered for inclusion in the proposed scoping review. Papers that are conference abstracts or letters to the editor will not be considered for inclusion in this scoping review.

Gray literature consisting of dissertations, theses, reports, or unpublished papers that examine how social factors affect nutrition risk or that describe social interventions designed to address nutrition risk will also be considered for inclusion.

Study or Source of Evidence Selection

Following the search, all identified citations will be collated and uploaded into EndNote 21 and duplicates will be removed. Citations will then be uploaded to Covidence. Following a pilot test, titles and abstracts will then be screened by 2 or more independent reviewers for assessment against the inclusion criteria for the review. Potentially relevant sources will be retrieved in full, and their full texts will be imported into Covidence. The full text of selected citations will be assessed in detail against the inclusion criteria by 2 independent reviewers. Reasons for the exclusion of sources of evidence in full text that do not meet the inclusion criteria will be recorded and reported in the scoping review. Any disagreements that arise between the reviewers at each stage of the selection process will be resolved through discussion, or with additional reviewers. The results of the search and the study inclusion process will completely be reported in the final scoping review and presented in the PRISMA-ScR flow diagram [ 29 ].

Data Extraction

Data will be extracted from sources of evidence included in the scoping review by 2 independent reviewers, using an adaptation of the Covidence data extraction tool as shown in Textbox 2 . The extraction tool is based on the JBI guidelines for data extraction and the default Covidence extraction tool. The data extracted will include specific details about the participants, concept, context, study methods, and key findings relevant to the review questions (social factors associated with nutrition risk). Data will be extracted verbatim from the included sources.

The data extraction tool will be further modified and revised, if necessary, during the process of extracting data from each included evidence source. Modifications will be detailed in the scoping review. Any disagreements that arise between the reviewers will be resolved through discussion, or with an additional reviewer. If appropriate, authors of papers will be contacted to request missing or additional data, where required.

General information

Study characteristics

  • Study design
  • Study methods
  • Dates (start date, end date, and length of follow-up period for longitudinal studies)
  • Study funding sources
  • Possible conflicts of interest for study authors
  • Population description
  • Inclusion criteria for study
  • Exclusion criteria for study
  • Recruitment methods
  • Total number of participants
  • Baseline population characteristics

Main findings

  • SCREEN-3 (Seniors in the Community Risk Evaluation for Eating and Nutrition-3)
  • SCREEN-8 (Seniors in the Community Risk Evaluation for Eating and Nutrition-8, formerly SCREEN II AB)
  • SCREEN-14 (Seniors in the Community Risk Evaluation for Eating and Nutrition-14, formerly SCREEN II)
  • SCREEN/SCREEN I (Seniors in the Community Risk Evaluation for Eating and Nutrition/Seniors in the Community Risk Evaluation for Eating and Nutrition I)
  • MNA (Mini Nutritional Assessment)
  • MNA-SF (Mini Nutritional Assessment-Short Form)
  • SGA (Subjective Global Assessment)
  • DETERMINE (Determine your health checklist)
  • SNAQ (Short Nutritional Assessment Questionnaire)
  • MUST (Malnutrition Universal Screening Tool)
  • Other (describe)
  • Social support
  • Social influence
  • Social participation
  • Commensality (eating with others)
  • Living situation (alone or with others)
  • Social networks or social network types
  • Social capital
  • Social standing
  • Social isolation
  • Measures of social factors (social factor and how it was measured)
  • Found a relationship between social factors and malnutrition and nutrition risk (yes, no, or other)
  • Description of the relationship between social factors and malnutrition and nutrition risk

Additional information for intervention studies

  • Description of intervention
  • Time points (number and time between time points)
  • Outcomes at different time points

Additional information for trials

  • Description of control group
  • Comparison of intervention group to control group

Data Analysis and Presentation

Social factors associated with nutrition risk or malnutrition risk will be reported in the scoping review, as will any social interventions that affect nutrition risk or malnutrition risk. Data will be analyzed to identify the common social factors that have been examined in conjunction with nutrition risk and to identify which social factors and interventions have been found to affect nutrition risk. Similarities and differences between findings will be noted; for example, differences in the tools used to measure nutrition risk, differences in how the various social factors were measured, and whether a social factor was consistently associated with nutrition risk across all (or the majority of) studies. Data from studies included in this review will be presented as a narrative summary with the use of tables. The tables will be used to highlight central concepts described in the narrative summary.

The scoping review was started in October 2023 and will be finalized by August 2024. As of May 28, 2024, a total of 5064 studies have been identified through database searches and imported for title and abstract screening, and 293 duplicates have been removed (266 duplicates identified by Covidence and 27 duplicates identified manually). Title and abstract screening has been completed, resulting in 235 full-text studies ready to be assessed for eligibility. The results of this scoping review will provide a comprehensive understanding of the social factors associated with nutrition risk in community-dwelling older adults in HICs.

Expected Outcomes

This scoping review will identify which social factors have been examined concerning nutrition risk in the literature and which social factors have been shown to impact nutrition risk. It will also identify any social interventions that have successfully reduced the prevalence of nutrition risk. The results of the review are anticipated to aid in identifying individuals who should be screened proactively for nutrition risk by identifying the social factors associated with increased risk. If the literature shows that certain social factors are consistently associated with increased nutrition risk, then screening programs can target individuals who reflect those social factors, for example, individuals with low levels of social support [ 17 , 22 ], low levels of social participation [ 3 , 17 ], or those who are socially isolated [ 3 , 11 , 22 , 38 ].

The results of this review will also inform programs and policies designed to reduce the prevalence of nutrition risk and help guide the development of interventions aimed at reducing nutrition risk through the identification of interventions that have affected nutrition risk and social factors that impact nutrition risk.

Gaps in the literature exploring social factors associated with nutrition risk will also be identified by noting which social factors have not been well-studied in the literature. This will help inform future research into nutrition risk and social factors.

Strengths and Limitations

A strength of this scoping review is the use of the JBI methodology for scoping reviews [ 28 ], and the PRISMA-ScR [ 29 ]. All screening and data extraction will be completed by at least 2 reviewers, out of whom at least 1 is a registered dietitian with experience in working with older adults in the community. Any disagreements between the reviewers will be resolved through discussion or by a third reviewer.

Due to many different tools that can be used to measure nutrition risk in community-dwelling older adults and due to the many ways that social factors can be measured, it is anticipated that there will be significant heterogeneity between studies. This information will be captured in the data extraction tool and will be discussed in the scoping review.

Conclusions

With the high prevalence of nutrition risk in community-dwelling older adults in HICs and the negative consequences of nutrition risk, it is essential to understand the social factors associated with nutrition risk. The Canadian Malnutrition Task Force has identified that research into the root causes of nutrition risk in community-dwelling older adults is a priority [ 39 ], and this scoping review will help to identify the potential social factors that may be the root causes of nutrition risk among this demographic.

Conflicts of Interest

None declared.

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Abbreviations

high-income country
low- and middle-income country
Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews

Edited by A Mavragani; submitted 24.01.24; peer-reviewed by P Voorheis, C Chan; comments to author 21.02.24; revised version received 10.03.24; accepted 02.04.24; published 25.06.24.

©Christine Marie Mills, Liza Boyar, Jessica A O’Flaherty, Heather H Keller. Originally published in JMIR Research Protocols (https://www.researchprotocols.org), 25.06.2024.

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Published on 25.6.2024 in Vol 26 (2024)

Effectiveness of Web-Based Mindfulness-Based Interventions for Patients With Cancer: Systematic Review and Meta-Analyses

Authors of this article:

Author Orcid Image

  • Ting Wang * , MNS   ; 
  • Chulei Tang * , PhD   ; 
  • Xiaoman Jiang, MSc   ; 
  • Yinning Guo, MNS   ; 
  • Shuqin Zhu, PhD   ; 
  • Qin Xu, MM  

School of Nursing, Nanjing Medical University, Nanjing, China

*these authors contributed equally

Corresponding Author:

School of Nursing, Nanjing Medical University

101 Longmian Avenue, Jiangning District

Nanjing, 211166

Phone: 86 13601587208

Email: [email protected]

Background: Cancer has emerged as a considerable global health concern, contributing substantially to both morbidity and mortality. Recognizing the urgent need to enhance the overall well-being and quality of life (QOL) of cancer patients, a growing number of researchers have started using online mindfulness-based interventions (MBIs) in oncology. However, the effectiveness and optimal implementation methods of these interventions remain unknown.

Objective: This study evaluates the effectiveness of online MBIs, encompassing both app- and website-based MBIs, for patients with cancer and provides insights into the potential implementation and sustainability of these interventions in real-world settings.

Methods: Searches were conducted across 8 electronic databases, including the Cochrane Library, Web of Science, PubMed, Embase, SinoMed, CINAHL Complete, Scopus, and PsycINFO, until December 30, 2022. Randomized controlled trials involving cancer patients aged ≥18 years and using app- and website-based MBIs compared to standard care were included. Nonrandomized studies, interventions targeting health professionals or caregivers, and studies lacking sufficient data were excluded. Two independent authors screened articles, extracted data using standardized forms, and assessed the risk of bias in the studies using the Cochrane Bias Risk Assessment Tool. Meta-analyses were performed using Review Manager (version 5.4; The Cochrane Collaboration) and the meta package in R (R Foundation for Statistical Computing). Standardized mean differences (SMDs) were used to determine the effects of interventions. The Reach, Effectiveness, Adoption, Implementation, and Maintenance framework was used to assess the potential implementation and sustainability of these interventions in real-world settings.

Results: Among 4349 articles screened, 15 (0.34%) were included. The total population comprised 1613 participants, of which 870 (53.9%) were in the experimental conditions and 743 (46.1%) were in the control conditions. The results of the meta-analysis showed that compared with the control group, the QOL (SMD 0.37, 95% CI 0.18-0.57; P <.001), sleep (SMD −0.36, 95% CI −0.71 to −0.01; P =.04), anxiety (SMD −0.48, 95% CI −0.75 to −0.20; P <.001), depression (SMD −0.36, 95% CI −0.61 to −0.11; P =.005), distress (SMD −0.50, 95% CI −0.75 to −0.26; P <.001), and perceived stress (SMD −0.89, 95% CI −1.33 to −0.45; P =.003) of the app- and website-based MBIs group in patients with cancer was significantly alleviated after the intervention. However, no significant differences were found in the fear of cancer recurrence (SMD −0.30, 95% CI −1.04 to 0.44; P =.39) and posttraumatic growth (SMD 0.08, 95% CI −0.26 to 0.42; P =.66). Most interventions were multicomponent, website-based health self-management programs, widely used by international and multilingual patients with cancer.

Conclusions: App- and website-based MBIs show promise for improving mental health and QOL outcomes in patients with cancer, and further research is needed to optimize and customize these interventions for individual physical and mental symptoms.

Trial Registration: PROSPERO CRD42022382219; https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=382219

Introduction

The 2020 Global Cancer Statistics Report estimates that there are 19.3 million new cases of cancer worldwide and approximately 10 million cancer-related deaths [ 1 ]. The leading cause of disease and mortality among humans today is cancer [ 2 , 3 ]. The physical symptoms of patients with cancer have been alleviated because of the continuous advancement of medical technology, but the psychological problems of patients with cancer have not been adequately treated. The process of treating cancer is typically complex, with many patients experiencing negative side effects of cancer treatments, such as chemotherapy and radiation therapy, that may impact their mental health, quality of life (QOL), and sleep quality. Targeted interventions to address these cancer-related symptoms can reduce the psychological burden of cancer treatment and diagnosis, which is critical to improving patients’ QOL and promoting their health [ 4 ]. With an increasing number of patients with cancer and a desire for physical and mental health, cancer care research is focusing on identifying the psychological problems of patients with cancer and developing and implementing patient-centered psychological care plans [ 5 , 6 ]. Rehabilitation for patients with cancer increasingly uses mental health as a therapeutic strategy; however, effective psychological intervention strategies are still urgently needed to satisfy the demands of patients with cancer [ 7 ].

Mindfulness-based interventions (MBIs) have emerged as promising intervention techniques for patients with cancer. Mindfulness can be defined as the ability to observe thoughts, bodily sensations, or feelings in the present moment with an open and accepting orientation toward one’s experiences [ 8 ]. MBIs, which incorporate mindfulness practices into various therapies in mental health care, have been found to increase psychological flexibility and alleviate intense emotional states. MBIs can include additional mental training, such as mindfulness-based stress reduction (MBSR) [ 9 ], and acceptance and commitment therapy [ 10 ], which addresses psychological issues by increasing psychological flexibility [ 11 ]. Cognitive-behavioral therapy has been combined with MBSR, resulting in mindfulness-based cognitive therapy (MBCT) for preventing depression relapses [ 12 ]. Mindfulness-based cancer recovery (MBCR), an adaptation of MBSR, comprises contents tailored for patients with cancer [ 13 ]. Through facilitating awareness and nonjudgmental acceptance of moment-to-moment experiences, these MBIs are presumed to alleviate intense emotional states. Mindfulness interventions have been shown to improve the psychological status of patients with cancer [ 14 , 15 ].

The rapid development of information technologies has led to the delivery of MBIs via the internet, which is more practical than face-to-face interaction and can overcome time and geographic barriers, and it has been established that online MBIs are more suitable for people with psychological and physical symptoms [ 16 ]. Implementing psychological interventions through online or remote health can be a potential cost benefit for current referral pathways and treatment models [ 17 ]. online MBIs can be used as the adjunctive therapy in patients with cancer to manage cancer-related symptoms [ 18 ].

Despite the increasing popularity of online mindfulness-based therapies for patients with cancer and the growing number of randomized controlled trials (RCTs) examining such programs, there has not been a systematic review of these studies and their descriptions of the interventions regarding their characteristics (eg, delivery mode and approach). To date, only 2 systematic reviews addressing the impact of online interventions on health outcomes in patients with cancer have been published. However, these reviews have notable limitations. The first review [ 19 ] only searched 4 databases, potentially leading to publication bias and compromising the reliability of the findings. Furthermore, this systematic review did not conduct sensitivity, subgroup, or meta-analyses. The second review [ 20 ] evaluated the validity of online MBIs on only 4 health outcomes: anxiety, depression, QOL, and mindfulness. However, the restricted quantity of RCTs and papers within each subgroup analysis poses a challenge in reaching definitive conclusions. In addition, the external validity (eg, generalizability or applicability) based on the RE-AIM (Reach, Effectiveness, Adoption, Implementation, and Maintenance) framework has not been examined in online MBIs for patients with cancer. Thus, attempts to synthesize the literature on the impact of online MBIs on the health of patients with cancer are limited, and there is a lack of analysis of the barriers and facilitators to the development of current online MBIs.

This systematic review aims to synthesize the effectiveness of online MBIs, encompassing both app- and website-based MBIs, for patients with cancer, comprehensively assessing a wide range of outcomes, including psychological, physiological, and QOL aspects. We conducted a comprehensive search to evaluate the validity of app- and website-based MBIs on psychological outcomes in patients with cancer, using high-quality RCTs to assess many health outcomes before and after treatment. Moreover, this study aims to provide an overview of the outcomes related to the interventions, including their effectiveness and potential for implementation and sustainability in real-world settings. We used the RE-AIM framework [ 21 ] to evaluate the potential for implementation and sustainability of these interventions in real-world settings. Using this framework, we can provide a comprehensive evaluation of an intervention’s potential impact and identify common traits of effective interventions. Overall, this study fills gaps in the literature by comprehensively evaluating the effectiveness and potential for implementation and sustainability of app- and website-based MBIs for patients with cancer.

Search Strategy

The protocol of this review was registered in PROSPERO (CRD42022382219) and written following the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) reporting guideline. The methods outlined in the protocol were strictly adhered to throughout the experimental procedures. The databases were searched until December 30, 2022. To identify relevant studies for inclusion in our systematic reviews, we developed comprehensive search strategies and used 8 databases: Cochrane Library, Web of Science, PubMed, Embase, SinoMed, CINAHL Complete, Scopus, and PsycINFO. The literature search language was limited to Chinese and English. The search strategies used a combination of subject headings (eg, Medical Subject Headings in PubMed) and keywords for the following 5 concepts: mindfulness, carcinoma, intervention, telemedicine, and randomly. Multimedia Appendix 1 shows detailed database search strategies. Reference lists of included studies and relevant systematic reviews were also manually searched for additional relevant studies. Search results were captured using citation management software, and duplicates were removed.

Inclusion and Exclusion Criteria

Because of the explorative nature of this meta-analysis, we opted for rather broad inclusion criteria. The inclusion criteria were as follows: (1) studies that included patients with cancer (aged ≥18 years) with any cancer type and stage, including those receiving anticancer treatment, those in remission, those considered cured, and those in the terminal phases of the disease; (2) studies that used MBIs (including MBSR, MBCT, and MBCR) and administered the MBI via the internet (including websites, web conferencing, web-based games, and web-based video) or a smartphone app; (3) studies in which eligible controls were required to receive standard care or usual care; (4) studies were eligible if a mental health outcome (eg, fear of cancer recurrence [FCR] as measured with the Fear of Cancer Recurrence Inventory [FCRI] and posttraumatic growth [PTG] as measured with the Posttraumatic Growth Inventory), anxiety, depression, distress, stress, and sleep) or QOL was assessed; and (5) the RCT was published in English or Chinese.

Exclusion criteria were (1) other types of studies (eg, observational, review, protocol, and case report); (2) studies of health professionals, caregivers, or mixed populations in which outcomes for survivors of cancer could not be extracted; and (3) insufficient information to calculate an effect size or determine eligibility.

Screening and Data Extraction

Two reviewers independently screened all titles and abstracts; then, they independently screened full-text articles, and conflicts were resolved by consensus. Data were independently extracted by 2 reviewers using a data extraction form adapted from the Cochrane Handbook [ 22 ] and reported using PRISMA guidelines [ 23 ]. We extracted data from included trials using standardized data extraction forms. Study-level variables included the year of publication, country of study, age of participants, cancer diagnosis, delivery mode, reminder, cancer-adapted MBIs, primary and secondary outcomes, intervention and follow-up durations, intervention and control group details, outcome measurement metrics, and outcomes scores up to postintervention. Any discrepancy or uncertainties were resolved through regular meetings and discussion among the research team.

Risk-of-Bias Assessment

The risk of bias was independently assessed by 2 reviewers using the Cochrane Risk-of-Bias tool, with differences reconciled through discussion [ 24 ]. A total of 6 domains encompassed random sequence generation, allocation concealment, blinding of participants and personnel, blinding of outcome assessment, incomplete outcome data, and selective outcome reporting. Each domain was judged as low, high, or unclear risk. Discrepancies in assessments between the 2 reviewers were resolved by consensus or by a third reviewer as required.

Meta-Analytic Method

This study conducted a meta-analysis using Review Manager (version 5.4; The Cochrane Collaboration) and the meta package in R (R Foundation for Statistical Computing). The primary and secondary outcome mean and SD values at postintervention follow-up for intervention and control groups were converted to standardized mean difference (SMD), using Hedges g . The value of SMD <0.5 would be interpreted as small, SMD ≥0.5 as medium, and SMD ≥0.8 as large effect size [ 25 ]. Authors of studies with missing data were contacted through email. However, if no data were provided, a narrative synthesis would be conducted. The I 2 statistic was used to estimate the percentage of heterogeneity across the primary studies not attributable to random sample error alone. A value of 0% indicated no heterogeneity, and values of 25%, 50%, and 75% reflected low, moderate, and high degrees of heterogeneity, respectively [ 26 ]. Acknowledging differences across studies because of the varied population, length of intervention, and length of follow-up, meta-analyses were performed fitting random effects models [ 27 ]. In addition, subgroup analyses were conducted to examine effect sizes across different subgroups; the specific moderating variables included technology, sex, intervention type, intervention duration, study quality, and scale.

RE-AIM Framework

The RE-AIM framework is a valuable tool for evaluating interventions in health care [ 28 ]. Its 5 dimensions assess an intervention’s potential for large-scale adoption, implementation, and sustainability, providing a comprehensive evaluation of its real-world efficacy and viability [ 29 ]. Reach refers to the extent of successfully targeting and engaging the intended audience, evaluated using the percentage of eligible patients enrolled in the study (n enrolled/n eligible). Efficacy measures the effect on outcomes such as mental health and QOL. Effect sizes (95% CIs) for the primary outcome were used to assess efficacy. Adoption measures the extent to which organizations or health care providers are willing and able to offer the intervention to their patients or clients, and barriers to adoption are evaluated by who recruited participants and where the intervention was offered. Implementation evaluates how effectively the intervention is delivered and received by patients, including factors such as adherence and fidelity, and is evaluated by measures such as adherence to the intervention, percentage of dropouts of the most complex intervention (n postintervention follow-up/n baseline×100), intervention cost, and author-reported plans to upscale or implement. Maintenance measures the extent to which the intervention can be sustained over time and integrated into routine care, and it is evaluated by the duration of results and the author-reported availability of the intervention [ 30 ].

Description of Studies

The systematic search revealed 4349 original articles, of which 54 (0.12%) were assessed at full-text level, and 15 (0.03%) studies were included in the final synthesis. Figure 1 displays the study flowchart of the search results and Table 1 presents the characteristics extracted from the included literature in the study. The total population comprised 1613 participants, of which 870 (53.94%) and 743 (46.06%) were in the experimental and control conditions, respectively. In most (13/15, 87%) studies, the majority of participants were women. Participants were aged from 41.84 to 66.45 years. Four studies were based on MBCR, 3 on MBCT, 2 on MBSR, and 6 on mindfulness-based programs. The 6 studies included interventions that were indeed rooted in mindfulness practices; however, they did not strictly adhere to the conventional frameworks of MBCT, MBCR, or MBSR. Instead, they used a variety of mindfulness-based approaches tailored to their respective study populations.

Furthermore, these studies did not specify the exact intervention methods used but were categorized as mindfulness-based programs . Because of the unique nature of these interventions, we cannot determine whether they belong to MBCT, MBCR, or MBSR interventions; we have categorized them as mindfulness-based programs , encompassing diverse methodologies beyond the traditional MBCT, MBCR, or MBSR frameworks. Trials used usual care (8 trials) and waitlists (7 trials) equally as comparators. Six studies had participants with breast cancer, 7 with mixed cancer types, and 2 with other cancer types. Five studies were conducted in China; 5 in the United States; and 1 each in the Netherlands, Denmark, Iran, Australia, and Canada.

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Study; countryCancer type; age (y), mean (SD); gender (female; %)Intervention (n); delivery modeRemindersIntervention duration, number of sessions; intervention doseCancer adaptedTechnologyControl group (n)MeasurementsOutcomes: measure instrument
Chang et al [ ], 2022; ChinaBreast; 49.6 (12.0); 100MBSR (41); web-based software and digital interactive whiteboard6 wk, 6 sessions; 2 h/wkWebsiteWaitlist (26)Pre and postDepression, anxiety, and stress: DASS-21
Compen et al [ ], 2018; NetherlandsMixed; 51.7 (10.7); 85MBCT (90); email, meditation audio file, and written feedback8 wk; 40-45 min/d twice dailyWebsiteUsual care (78)Pre and postDistress: HADS , FCR : FCRI , and QOL : SF-12
Kubo et al [ ], 2019; USMixed; 58.2 (14.4); 68MBP (54); audio instruction, lecture videos, and foundation courseStudy staff made phone calls if an intervention participant completed <38 wk, 2 h/wkSpecifically for individuals affected by cancerAppUsual care (43)Pre and postDistress: NCCN , anxiety and depression: HADS, PTG : PTGI , sleep: PROMIS , and QOL:FACT-G
Kubo et al [ ], 2018; USMixed; 66.5 (9.7); 69MBP (52); online classroom and manualThe app can send reminders using push notifications; study staff made phone calls if an intervention participant completed <36 wk; 2 h/wkCancer pack, which was designed specifically for individuals affected by cancerAppUsual care (51)Pre and postQOL: FACIT−Pal , distress: NCCN, and anxiety and depression: HADS
Liu et al [ ], 2022; ChinaHCC ; 55.7 (8); 22MBCT (61); WeChat audio and online platformsEvery day (texting)6 wk, 20 min/d for 5 d/wkAdoption of the main issues and needs of patients with HCCAppWaitlist (61)Pre, post, 1 mo FU , 3 mo FUDistress: HADS, sleep: PSQI , QOL: FACT-hep , and stress: PSS
Messer et al [ ], 2020; USMixed; 51 (10.6); 76MBSR (11); guided meditation audio clips and brief textual lessons6 wk; mean duration of 12 min/sessionWebsiteUsual care (10)Pre and postDistress: HADS, QOL: POMS-SF , and sleep: PSQI
Nissen et al [ ], 2018; DenmarkBreast and prostate; 55.9 (12.1); 91MBCT (104); website written material, audio exercises, writing tasks, and videos10 wk, 10 sessions; 2 h/wk for 45 min/dProgram adjustments to meet the needs of survivors of cancerWebsiteWaitlist (46)Pre, post, and 6 mo FUAnxiety: STAI‐Y , depression: BDI‐II , stress: PSS‐10, and sleep: ISI
Peng et al [ ], 2022; ChinaBreast; 41.8 (2.9); 100MBP (30); website meeting 5P medicine approach6 wk, 6 sessions; 1.5 h/wkOn the basis of specific considerations for survivors of cancerAppUsual care (30)Pre, post, and 1 mo FUFCR: FCRI-SF and QOL: Eortc-Qlq-C30
Rosen [ ], 2017; USBreast; 53 (10.3); 100 MBP (48); app-based courses include audio and videoGeneral weekly check-in emails9 wkAppWaitlist (47)Pre, wk 5, wk 9, and wk 4 FUQOL: FACT-B
Rosen et al [ ], 2018; USBreast; 51.6 (10.3); 100 MBP (57); app-based audio and animated videoWeekly check-in email9 wkAppWaitlist (55)Pre, post, and 1 mo FUQOL: FACT‐B
Russell et al [ ], 2019; AustraliaMelanoma; 53.4 (13.1); 54MBP (46); embedded short videos, PDF transcript of the videos, and MP3 audio emailAutomatically generated email reminders twice daily6 wkSurvey to understand the knowledge of meditation among people with melanomaWebsiteWaitlist (23)Pre and postFCR: FCRI and stress: PSS-10
Shen et al [ ], 2021; ChinaBreast; 47.4 (7.5); 100MBCR (37); online course, WeChat group, audio-video materials, and picturesEvery day (texting)8 wk, 8 sessions; 15 min/d for 6 d/wkCombine rich experience in rehabilitation psychotherapy of breast cancerAppUsual care (40)Pre and postStress: CPSS and anxiety: SAS
Wang [ ], 2022; ChinaBreast; 46.8 (7.9); 100MBCR (51); web-based courses and intervention materials4 wk, 4 sessions; 1.5 h/wk and 30 min dailyOn the basis of the problems in the pilot study and participant feedback, adjusted internet-delivered MBCR programWebsiteUsual care (52)Pre and postQOL: FACT-B
Yousefi et al [ ], 2022; IranColorectal and stomach; 54.9 (6.6); 42MBCR (25); web-based sessionAn alert reminder message was sent 2 h before each session9 wk, 9 sessions; 90 min/wkCancer-specific MBSR program was used in the studyWebsiteUsual care (25)Pre, post, and 2 mo FUStress: DASS‐21 and sleep: ISI
Zernicke et al [ ], 2014; CanadaMixed; 58 (10.7); 72MBCR (30); web-based classroom, guided meditation recordings, and videos8 wk, 8 sessions; 45 min/dCancer-adapted MBSRWebsiteWaitlist (32)Pre and postDepression and anxiety: POMS , stress: CSOSI , PTG: PTGI

a MBSR: mindfulness-based stress reduction.

b Not applicable.

c DASS-21: Depression, Anxiety, and Stress Scale-21.

d MBCT: mindfulness-based cognitive therapy.

e HADS: Hospital Anxiety and Depression Scale.

f FCR: fear of cancer recurrence.

g FCRI: Fear of Cancer Recurrence Inventory.

h QOL: quality of life.

i SF-12: 12-item Short-Form health survey.

j MBP: mindfulness-based program.

k NCCN: National Comprehensive Cancer Network Distress Thermometer.

l PTG: posttraumatic growth.

m PTGI: 21-item Posttraumatic Growth Inventory.

n PROMIS: 8-item PROMIS Sleep Disturbance scale.

o FACT-G: 27-item Functional Assessment of Cancer Therapy General Scale.

p FACIT‐Pal: 46-item Functional Assessment of Chronic Illness Therapy—Palliative Care.

q HCC: hepatocellular carcinoma.

r FU: follow-up.

s PSQI: Pittsburgh Sleep Quality Index.

t FACT-Hep: Functional Assessment of Cancer Therapy-Hepatobiliary Carcinoma.

u PSS: Perceived Stress Scale.

v POMS-SF: Profile of Mood States-Short Form.

w STAI‐Y: State-Trait Anxiety Inventory Y-Form.

x BDI‐II: Beck Depression Inventory.

y ISI: Insomnia Severity Index.

z 5P: The specific name of an application designed to promote mind and brain health and cultivate happiness.

aa FCRI-SF: Fear of Cancer Recurrence Inventory-Short Form.

ab Eortc-Qlq-C30: European Organization for Research and Treatment of Cancer questionnaire.

ac FACT-B: Functional Assessment of Cancer Therapy-Breast version 4.

ad MBCR: Mindfulness-based cancer recovery.

ae CPSS: Chinese version of the Perceived Stress Scale.

af SAS: Self-Rating Anxiety Scale.

ag POMS: Profile of Mood States.

ah CSOSI: Calgary Symptoms of Stress Inventory.

Risk of Bias

The risk-of-bias assessment is presented in Multimedia Appendix 2 [ 31 - 45 ]. Most studies (9/15, 60%) adequately generated and concealed allocation ( Figure 2 ). In most studies (14/15, 93%), patient blinding was not possible because of the nature of online MBIs and was not considered to increase the risk of bias. However, of the 15 studies, 8 (53%) [ 31 , 33 , 37 - 40 , 42 , 44 ] presented insufficient information regarding researcher and outcome assessor blinding, whereas 7 (47%) reported blinding researchers [ 32 , 34 - 36 , 41 , 43 , 45 ] (low risk). A total of 14 studies reported complete outcome data (low risk), and 1 study had insufficient detail [ 44 ] (unclear risk). In 1 study [ 40 ], attrition was high and comparisons or reasons for attrition were not provided. Finally, 66% (10/15) of the studies did not reference a protocol or trial registration (unclear risk).

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Meta-Analysis

Effects on qol.

A total of 8 studies reported the effects of app- and website-based MBIs on QOL among patients with cancer. To measure QOL in patients with cancer, 4 health-related QOL measures were used, including the Functional Assessment of Chronic Illness Therapy [ 34 ], the Functional Assessment of Cancer Therapy [ 33 , 35 , 39 , 40 , 43 ], the Short-Form 12 [ 32 ], and the European Organization for Research and Treatment of Cancer questionnaire [ 38 ], all of which have been validated in this patient population. Higher scores reflected a higher QOL. Because the physical and psychological components of the scale were measured separately and it was not possible to determine the overall change in the QOL, the data from 1 study [ 32 ] were not summarized. A total of 7 studies including 569 participants were evaluated in the meta-analysis. No significant heterogeneity was found between studies ( I 2 =26%; P =.23; Figure 3 [ 33 - 41 , 43 - 45 ]). The intervention group had a significant QOL improvement compared to the control group (SMD 0.37, 95% CI 0.18-0.57; P <.001). In addition, the exclusion of any single study at one time did not change the pooled results markedly.

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Effects on Sleep

Five studies investigated the impact of app- and website-based MBIs on sleep quality using 3 assessment tools: the 8-item PROMIS Sleep Disturbance scale [ 33 ], the Insomnia Severity Index [ 37 , 44 ], and the Pittsburgh Sleep Quality Index [ 35 , 36 ]. A higher score indicated a worse sleep quality. Moderate heterogeneity of effect sizes was observed ( I ²=58%; P =.05; Figure 3 ). Grouping the studies by type of technology, scale, and intervention type did not resolve heterogeneity, so a random effects model was chosen to pool the results. The result revealed that app- and website-based MBIs could alleviate patients’ sleep issues, with a statistical difference (SMD −0.36, 95% CI −0.72 to −0.01; P =.04). Only 1 outlier was detected [ 36 ]. After omitting the studies from the analysis, the effect size dropped to an SMD of −0.25 (95% CI −0.54 to 0.04; P =.09), and heterogeneity reduced substantially ( I 2 =38%). The possible reason for this change may be attributed to the fact that small sample sizes tend to yield more pronounced effects.

Effects on FCR

A total of 3 studies measured FCR; the pooled data included 224 participants. Two FCR measures were used: FCRI [ 32 , 41 ] and the Short-Form FCRI [ 38 ]. A higher score indicated a higher level of FCR. There is great heterogeneity among the studies ( I 2 =86%; P =.009; Figure 3 ). After the data of the study by Russell et al [ 41 ] are eliminated by the method of eliminating one by one, there is significantly lower heterogeneity ( I 2 =0%; P =.70). This may be due to Russell et al [ 41 ] presurveying patients with cancer so that the intervention on FCR was more effective. The results showed that the difference between the network-based MBIs and the control group was not statistically significant (SMD −0.30, 95% CI −1.04 to 0.44; P =.39).

Effects on PTG

Two studies examined the effect of app- and website-based MBIs on PTG, with a total of 134 participants. The measurement tool exclusively used across 2 studies to assess PTG was the Posttraumatic Growth Inventory [ 33 , 45 ]. Higher scores indicated greater PTG. No significant heterogeneity was found between studies ( I 2 =0%; P =.38; Figure 3 ). We found that app- and website-based MBIs did not lead to a significant increase in PTG score (SMD 0.08, 95% CI −0.26 to 0.42; P =.66).

Effects on Anxiety

Anxiety levels were assessed in 6 studies using 5 validated scales. These scales include the Hospital Anxiety and Depression Scale (HADS) [ 33 , 34 ], the Depression Anxiety Stress Scale Depression Inventory [ 31 ], the State-Trait Anxiety Inventory Y-Form [ 37 ], the Self-Rating Anxiety Scale [ 42 ], and the Profile of Mood States [ 45 ]. Higher scores on these scales indicated elevated levels of anxiety. Meta-analysis showed that app- and website-based MBIs lead to a significant reduction in anxiety (SMD −0.48, 95% CI −0.75 to −0.20; P <.001; Figure 4 [ 31 - 37 , 41 , 42 , 44 , 45 ]). Moderate heterogeneity was found between studies ( I 2 =52%; P =.07). Grouping the studies by type of technology and intervention duration did not resolve heterogeneity ( Table 2 ). Furthermore, when we examined subgroups based on sex, we found that studies including female participants had a significantly larger pooled effect size (SMD −0.67, 95% CI −1.01 to −0.33; P <.001) than the studies including both male and female participants (referred to as the mixed-gender subgroup; SMD −0.39, 95% CI −0.76 to −0.02; P =.04; Figure 4 ). The differences across these 2 subgroups were statistically nonsignificant (χ 2 1 =1.2; P =.28).

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Subgroup and stratificationStudies, n (%)SMD (95% CI) value for heterogeneity value for pooled results value for interaction

.54


Website 3 (50)−0.57 (−0.82 to −0.31).470.0001


App3 (50)−0.38 (−0.93 to 0.18).0274.18

.43


<8 wk 2 (33)−0.62 (−0.97 to−0.27).570<.001


≥8 wk 4 (67)−0.41 (−0.81 to −0.01).0367.04

.28


Female 2 (33)−0.67 (−1.01 to −0.33).410<.001


Mixed 4 (67)−0.39 (−0.76 to −0.02).0562.04

.67


MBCR 2 (33)−0.70 (−0.05 to −0.36).550<.001


MBCT 1 (17)−0.43 (−0.82 to 0.03).04


MBIs 2 (33)−0.28 (−1.14 to 0.59).0185.53


MBSR 1 (17)−0.52(−1.02 to −0.02).04

.07


Unclear risk 5 (83)−0.43 (−0.74 to −0.12).0656.007


High risk 1 (17)−0.72 (−1.20 to −0.24).004

.68


Website 4 (80)−0.87 (−1.44 to −0.29).00280.003


App1 (20)−1.02 (−1.50 to −0.55)<.001

<.001


MBCR 3 (60)−0.96 (−1.27 to−0.66).390<.001


MBCT1 (20)−0.21 (-0.61 to 0.18).29


MBIs1 (20)−1.41 (−1.97 to −0.86)<.001

.33


PROMs 1 (20)−0.09 (−0.55 to 0.38).72


PSQI 2 (40)−0.78 (−1.58 to 0.02).1160.05


ISI 2 (40)−0.23 (−0.83 to 0.36).0965.44

.20


Website3 (60)−0.52 (−1.22 to 0.19).0275.15


App2 (40)−0.02 (−0.32 to 0.28).700.91

.16


<8 wk2 (40)−0.78 (−1.58 to −0.02).1160.05


≥8 wk3 (60)−0.16 (−0.49 to 0.17).2332.35

.11


Unclear risk4 (80)−2.03 (−2.93 to −1.13).1249<.001


High risk1 (20)0.20 (−2.93 to 2.79).88

a SMD: standardized mean difference.

b MBCR: mindfulness-based cancer recovery.

c MBCT: mindfulness-based cognitive therapy.

d Not applicable.

e MBI: mindfulness-based intervention.

f MBSR: mindfulness-based stress reduction.

g Unclear risk: unclear risk of bias for one or more key domains.

h High risk: high risk of bias for one or more key domains.

i PROM: patient‐reported outcome measure.

j PSQI: Pittsburgh Sleep Quality Index.

k ISI: Insomnia Severity Index.

Effects on Depression

Depression was assessed across 5 studies using various standardized instruments. These included the Depression Anxiety Stress Scale-21 [ 31 ], HADS [ 33 , 34 ], Beck Depression Inventory [ 37 ], and Profile of Mood States [ 45 ]. Elevated levels of depression were indicated by higher scores on these scales. The pooled data included 384 participants and showed a significant difference in improvement between the intervention and control groups (SMD −0.36, 95% CI −0.61 to −0.11; P =.005; Figure 4 ). Moderate heterogeneity of effect sizes was observed ( I 2 =31%; P =.21). In the sensitivity analysis using the one-study-out method, we found that the pooled estimates were not significantly altered when any 1 study was omitted in turn. The range of P values obtained varied from .0001 to .03, indicating that the summary effect size is robust.

Effects on Perceived Stress

A total of studies investigated the effects of app- and website-based MBIs on stress. Four distress measures were used: the Perceived Stress Scale [ 35 , 37 , 41 ], the Chinese version of the Perceived Stress Scale [ 42 ], the Depression and Stress Scale [ 44 ], and the Calgary Symptoms of Stress Inventory [ 45 ]. A total of 5 studies including 366 participants were evaluated in the meta-analysis. The data from 1 study was not pooled because the mean values and SD of outcomes were not reported [ 35 ], and between-study heterogeneity was found ( I 2 =75%; P =.003; Figure 4 ). This meta-analysis revealed a reduction in stress of −0.89 (95% CI −1.33 to −0.45) when comparing the intervention group to the control group at the postintervention stage.

To further explore the potential sources of heterogeneity, we conducted subgroup analyses by type of technology and intervention type ( Table 2 ). The 2 studies using apps (SMD −1.02, 95% CI −1.50 to −0.55; I 2 =0) were found to have low heterogeneity, whereas the 3 studies based on website-based technologies (SMD −0.87, 95% CI −1.44 to −0.29; P =.002) exhibited higher heterogeneity. After conducting sensitivity analysis and eliminating 1 study at a time, the exclusion of the study by Nissen et al [ 37 ] resulted in significantly lower heterogeneity (I 2 =21%; P =.28). One possible reason is that the study by Nissen et al [ 37 ], which offered internet-delivered MBCT as a routine based on a screening procedure, may have included less motivated participants compared to studies with self-referral. In addition, Nissen et al [ 37 ] used a lower cutoff value for screening the study population, which could have resulted in a floor effect.

Effects on Distress

In the analysis of distress (involving 5 studies), HADS [ 32 , 35 , 36 ] and the National Comprehensive Cancer Network Distress Thermometer [ 33 , 34 ] were used to assess the current distress level. Low heterogeneity was found between studies ( I 2 =30%; P =.22; Figure 4 ), and the random effects model indicated that app- and website-based MBIs were associated with reduced distress levels in patients with cancer (SMD −0.50, 95% CI −0.75 to −0.26; P <.001).

Subgroup Analysis

Table 2 displays the results of subgroup analyses that were conducted to investigate the heterogeneity in the association between anxiety, perceived stress, and sleep in the context of MBIs. To explain the variability in the effects of mindfulness, we examined various moderating variables, such as technology, sex, intervention type, intervention duration, study quality, and scale. No statistically significant variables were found in the subgroup analysis of anxiety and sleep, whereas the type of intervention ( P <.001) was a significant moderating variable for perceived stress

Publication Bias

Funnel plots and statistical tests were not performed as any of the outcomes had at least 10 studies to ensure sufficient power in detecting asymmetry [ 46 ]. However, we reduced the possibility of publication bias by conducting a thorough search across multiple databases to identify published studies [ 47 ].

Details of the RE-AIM Framework assessment are presented in Multimedia Appendix 3 [ 31 - 45 ]. Of the 15 studies, 14 (93%) reported 13% to 92% of eligible patients. Efficacy (effect size and 95% CI of primary outcome) was reported in 33% (5/15) of the studies [ 33 , 35 , 37 , 39 , 40 ] (Cohen d or η 2 ). For adoption barriers, health professionals or researchers conducted recruitment for all studies, and 53% (8/15) of the studies [ 35 - 38 , 41 - 44 ] recruited participants in person (hospital and cancer center). For implementation, intervention adherence ranged from 59% to 100% of participants completing all scheduled components. Dropouts of most complex interventions ranged from 0% to 48%, with 40% (6/15) of the studies [ 31 , 38 - 40 , 42 , 45 ] having <10% dropouts. The cost was reported in 4 studies [ 33 , 34 , 39 , 40 ], including the paid app (priced at US $77 for 6 months and US $69.99 for 12 months) and the app already publicly available. In total, 46% (7/15) of the studies [ 35 , 37 - 40 , 43 , 44 ] reported maintenance of results, and 46% (7/15) of the studies [ 35 , 37 - 40 , 43 , 44 ] sustained results for 1 to 9 months. Four studies [ 33 , 34 , 39 , 40 ] explicitly reported on the potential for the interventions to remain accessible or whether there were plans for their continued implementation.

Principal Findings

The objective of this study is to assess the effectiveness of MBIs in improving the mental health and QOL of patients with cancer. We discovered that patients’ QOL can be greatly enhanced by app- and website-based MBIs, which also significantly lowers psychological distress, sleep problems, anxiety, depression, and perceived stress. This systematic review of meta-analyses and the RE-AIM framework demonstrate that app- and website-based interventions have a wide range of effects and are highly used by different (international and multilingual) patients with cancer. However, the use and accessibility of app- and website-based MBIs for patients with cancer have been constrained because of service fees and patient mobility limitations [ 48 ]; app- and website-based MBIs are mainly conducted in high-income countries. The possible explanation is the distinction between communication and economy; some high-income countries may have national health services in place to promote app- and website-based MBIs, whereas developing nations may not. Study shows that in many low- and middle-income countries, the accessibility of evidence-based mental health treatments remains limited [ 49 ]. The time commitment, teacher shortage, and high cost of classic mindfulness interventions may have hindered efforts to spread the associated benefits to individuals in developing countries [ 50 ]. For instance, Indonesia has yet to implement evidence-based internet-based mindfulness therapy, emphasizing the need for expanding evidence-based mental health interventions in resource-constrained settings.

The results of this study suggest that app- and website-based MBIs are effective in improving QOL and reducing anxiety and depressive symptoms in patients with cancer, which is consistent with previous meta-analyses [ 18 , 20 ]. A possible explanation for this is that app- and website-based MBIs can alleviate negative emotions, enhance positive emotions, and increase mindfulness skills among patients with cancer, as elaborated by previous research [ 51 ]. Moreover, the sleep quality of patients with cancer also improved after MBIs. This outcome may be attributed to the inclusion of techniques in the program that target sleep difficulties [ 7 ] and the nonjudging aspect of mindfulness, which can enhance sleep quality by mitigating stress and everyday tensions. Previous studies [ 52 ] have confirmed the moderate effect of mindfulness interventions on sleep quality, which suggests that the use of app- and website-based MBIs to manage QOL and sleep in patients with cancer should be further supported.

App- and website-based MBIs have shown potential in helping patients with cancer develop emotional regulation skills and cope with the distress associated with diagnosis and treatment [ 53 ]. It makes patients feel better emotionally and physically and helps patients with cancer reduce their psychological distress [ 54 ]. Incorporating MBIs into oncological treatment can promote emotional and physical well-being and alleviate psychological distress [ 55 ]. MBIs have been found to regulate biological variables associated with stress [ 56 ], such as immune function, hypothalamic-pituitary-adrenal regulation, and autonomic nervous system activity, thereby reducing pressure on patients. The data from this review showed that MBCR appeared to be particularly effective in reducing perceived stress, whereas MBCT was not effective in reducing stress after the intervention [ 51 ]. This finding was unexpected, given that many previous studies have suggested the effectiveness of MBCT in reducing stress [ 57 ]. However, because of the limited number of included studies, it is difficult to draw definitive conclusions regarding the comparative effectiveness of different MBIs.

However, although not statistically significant, app- and website-based MBIs can improve the level of PTG and FCR in patients with cancer. FCR is one of the most common problems of survivors of cancer, and it has been known that FCR can persist throughout the treatment and survival trajectory [ 58 ]; thus, specific intervention is needed for survivors of cancer who have clinically significant FCR. Previous meta-analysis showed that cognitive therapy and mindfulness exercises are very suitable for combating FCR [ 59 ]. Numerous psychological and behavioral mechanisms of change within mindfulness interventions have been suggested, encompassing acceptance, emotion regulation skills, and the reduction of ruminative thoughts [ 60 ]. The meta-analysis by Gu et al [ 61 ] provided empirical confirmation that rumination significantly mediates the impact of MBIs on mental health outcomes. In addition, the study by Butow et al [ 62 ] identified rumination as a crucial psychological mechanism associated with FCR. Therefore, the study suggests that the effectiveness of mindfulness interventions in addressing the FCR may be attributed to their potential to improve patients’ levels of rumination. The improved PTG observed in this study may be explained by the systematic training in moment-by-moment awareness, and MBIs focus on viewing thoughts and feelings as mental events [ 63 ]. Such a decentered relationship enables a perception of mental events as aspects of experience moving through awareness, showing that mindfulness practice supports personal growth and transformation.

In this study, it was observed that short-term MBIs with a duration of <8 weeks exhibited a larger effect size concerning the outcomes of anxiety and sleep. In the study by Wang et al [ 43 ], short-term MBIs were found to be more effective in improving physical health compared to long-term MBIs, and interventions lasting <8 weeks demonstrated a greater effect size, possibly attributed to the increased participant engagement resulting from the shorter intervention duration and simplified intervention complexity. Shorter interventions may be more feasible and acceptable for patients with cancer who are dealing with a range of physical and emotional challenges [ 64 ]. Future research should aim to replicate and expand on these results, including investigating the optimal duration and timing of app- and website-based MBIs for patients with cancer.

Recommendations for Future Research

To the best of our knowledge, this study represents the first meta-analysis using the RE-AIM framework, systematically reviewing and synthesizing the effectiveness of MBIs for patients with cancer across various types of interventions. By accurately reporting the RE-AIM dimensions, this study seeks to enhance the replicability and universality of mindfulness interventions in oncology settings. Our assessment of app- and website-based MBIs for patients with cancer, conducted within the framework of RE-AIM, reveals that the participation rates of eligible patients range from 13% to 92%. The calculated median participation rate, at 67% (IQR 47.5%-82%), emphasizes the effectiveness of the interventions in reaching a substantial portion of the target population. However, only a minority of studies reported on efficacy, which limited our ability to draw conclusions on overall effectiveness. Recruitment was primarily conducted by health professionals or researchers, and more than half of the studies (8/15, 53%) recruited participants in person, potentially limiting generalizability. Intervention adherence was generally high, but dropout rates varied widely, indicating that certain interventions may be more challenging for some patients. Cost was reported in only a few studies (4/15, 27%), with implications for accessibility. Long-term effects were reported in more than half of the studies (7/15, 47%), highlighting the need for further research. This study underscores the importance of considering the RE-AIM framework in the implementation and evaluation of these interventions. Further research is needed to fully understand their potential benefits and limitations in real-world settings.

Internet-based interventions have previously been shown to be effective for anxiety disorders and fear-related disorders and have achieved the same effect as face-to-face treatment [ 65 ]. Consistent with the results of this study, delivery via the internet, group, or app is feasible and effective. Our results suggest that among forms of online MBIs for patients with cancer, the most widely studied type was website-based interventions. This observation is in line with an analysis conducted in recent years [ 66 ], which indicated that the most widely studied type of telehealth for patients with breast cancer was website-based interventions. Website-based MBIs may offer more content, functionality, and instruction than app-based interventions, which may enhance user engagement, learning, and practice of positive thinking skills [ 67 , 68 ]. Website-based MBIs had higher completion rates and lower attrition rates compared to app-based interventions, which may be due to factors such as convenience, accessibility, engagement, and personalization [ 69 ]. Finally, in our review, a website-based study [ 41 ] that greatly improved FCR and stress highlighted the sustainability and self-management of the intervention and enabled flexible navigation by accessing website content according to user preferences. Therefore, website-based MBIs may offer more opportunities for personalization and tailoring interventions to individual needs.

In our analysis, 53% (8/15) of the studies implemented a weekly or daily reminder system through various channels, such as email, text messages, apps, or smartphone notifications, to facilitate app- and website-based MBIs. However, the prevalence of reminder systems in the studies under review is relatively limited (7/15, 47%), a finding consistent with the investigation by Matis et al [ 19 ]. Matis et al conducted a systematic evaluation in this field, discussing the limited prevalence of reminder systems in reviewed studies and highlighting the current lack of direct comparisons between interventions with and without reminders. In addition, the study found that the frequency of reminders was positively associated with the magnitude of the intervention effect [ 70 ]. Consequently, to promote patient involvement in app- and website-based MBIs, it is vital to set reminders [ 67 ]. Some studies have also set up expert feedback, answers, and a variety of supervision methods to avoid reduced patient compliance. Therefore, app- and website-based MBIs can enhance engagement using features such as reminders, feedback, personalization, and facilitator-led components. However, it is important to note that the specific frequency, timing, and content of the reminders may vary depending on the individual and the context of the intervention. Our study results reveal heterogeneity in the types, frequencies, and content of reminder systems, preventing the establishment of specific standards for their effectiveness. Despite the evident practicality of reminder systems, a more comprehensive investigation into their types, frequencies, and effectiveness is imperative within the context of app- and website-based MBIs.

This systematic review found that most app- and website-based interventions have adopted online classrooms; application-based measures to implement mindfulness interventions; and multicomponent interventions that include audio, video, and documents. However, the study did not clarify which factors affect behavioral changes. Despite these differences, 67% (10/15) of the interventions are designed specifically for the cancer population and provide customizable interventions. For example, as demonstrated by Wang et al [ 43 ], a pilot website-based MBIs was conducted for patients with cancer; this is an adapted version of MBSR specifically tailored for individuals dealing with cancer-related stressors. The MBCR program retains the core principles and practices of MBSR while integrating specific intervention materials to address challenges associated with cancer, such as common experiences related to cancer, sleep issues, pain, and FCR, which is greatly beneficial for improving the physical and mental symptoms of patients with cancer. MBCR will provide a platform for patients with cancer to engage in discussions and address challenges related to cancer. Future app- and website-based MBIs should take into account the characteristics of patients and determine which intervention plan is most suitable for patients with cancer, emphasizing feedback sessions and communication with therapists to enable patients to learn self-management and make intervention plans sustainable.

Limitations

Although this review summarizes international RCTs for various outcomes, there are limitations. First, because the research results are measured by various tools, it may hinder the comparability of research outcomes. Second, in the 15 trials, there are differences in the personnel, duration, and methods of app- and website-based MBIs in various studies. Patients included in these studies have different characteristics. Third, The inability to access or adequately translate studies in languages other than English and Chinese may introduce bias into the selection process, potentially limiting the comprehensiveness of the findings. Finally, in the subgroup analysis, the study of each subgroup is limited, which may reduce the ability to draw conclusions on the differences in the consistency of intervention effects between subgroups. The abovementioned factors may lead to heterogeneity between studies, which is closely related to the summary results, so these results need to be interpreted carefully. Nevertheless, the meta-analysis included RCTs only and used a random effect model to pool results to give the most conservative estimates. In addition, subgroup analysis and sensitivity analysis were conducted and showed that the pooled estimations were relatively robust.

Conclusions

This meta-analysis provides definite evidence regarding the efficacy of app- and website-based MBIs for patients with cancer. Our findings suggest that app- and website-based MBIs can be effective in improving OL, sleep, and mental health and can be integrated into stepped care in clinical practice. Future experiments should pay more attention to the development of intervention programs based on the wishes and characteristics of patients with cancer and study how to optimize interventions further and customize interventions based on individual physical and mental symptoms.

Acknowledgments

This study was supported by the Exploration of Trajectories and Intervention Program of Frailty for Gastric Cancer Survivors Based on the Health Ecology Theory project supported by the National Natural Science Foundation of China (number 82073407), the Studies on Construction of Core Competency Model and Development of Assessment Tool for Nurses of Hospice Care project supported by the National Natural Science Foundation of China (number 72004099), and the Basic Science (Natural Science) Foundation of Higher Education Institutions of Jiangsu Province (project number 22KJB320013).

Data Availability

All data generated or analyzed during this study are included in this published article and its supplementary information files.

Authors' Contributions

TW and XJ developed the key ideas for the manuscript and the hypotheses. TW developed the search strategy and conducted the literature searches. YG, XJ, and CT conducted screening and coding. QX, CT, and SZ contributed to manuscript review and editing. TW conducted the statistical analyses, summarized the findings, and prepared the initial draft of the manuscript. All authors contributed to and approved the final manuscript.

Conflicts of Interest

None declared.

Search strategy.

Summary of the risk of bias of studies included in the systematic review.

RE-AIM (Reach, Effectiveness, Adoption, Implementation, and Maintenance) framework.

Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) checklist.

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Abbreviations

fear of cancer recurrence
Fear of Cancer Recurrence Inventory
Hospital Anxiety and Depression Scale
mindfulness-based cognitive therapy
mindfulness-based intervention
mindfulness-based stress reduction
Preferred Reporting Items for Systematic Reviews and Meta-Analyses
posttraumatic growth
quality of life
randomized controlled trial
Reach, Effectiveness, Adoption, Implementation, and Maintenance
standardized mean difference

Edited by T de Azevedo Cardoso; submitted 30.03.23; peer-reviewed by J Luo, K Kershner, F Chio; comments to author 31.12.23; revised version received 26.03.24; accepted 23.04.24; published 25.06.24.

©Ting Wang, Chulei Tang, Xiaoman Jiang, Yinning Guo, Shuqin Zhu, Qin Xu. Originally published in the Journal of Medical Internet Research (https://www.jmir.org), 25.06.2024.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in the Journal of Medical Internet Research (ISSN 1438-8871), is properly cited. The complete bibliographic information, a link to the original publication on https://www.jmir.org/, as well as this copyright and license information must be included.

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